Results 181 to 190 of about 253,930 (319)

Insights into the Dynamics and Binding Mechanisms of the Alkhumra Virus NS2B/NS3 Protease: A Molecular Dynamics Study

Advanced Theory and Simulations, EarlyView.
The ΔRMSF$\Delta {\rm RMSF}$ analysis reveals significant flexibility differences between free NS3 and the NS2B/NS3 complex, with notable deviations in specific regions. Key residues driving NS2B binding are identified, and the protonation state of catalytic serine affects oxyanion hole formation.
Jurica Novak, Shivananda Kandagalla, Ramesh Sistla   +2 more
wiley   +1 more source

Author's response: Viral load decline time offers theoretical insight rather than practical value. [PDF]

Euro Surveill
Jonnerby J, Lalvani A, all co-authors of the original article.   +2 more
europepmc   +1 more source

Course of Viral Load Throughout HIV-1 Infection

, 2000
Caroline Sabin, Helen Devereux, Andrew Phillips, Andrew F. Hill, George Janossy, Christine A. Lee, Clive Loveday   +6 more
openalex   +1 more source

Autologous Peripheral Vγ9Vδ2 T Cell Synergizes with αβ T Cell Through Antigen Presentation and BTN3A1 Blockade in Immunotherapy of Cervical Cancer

Advanced Science, EarlyView.
This study provides proof‐of‐concept evidence showing that through direct killing, antigen presentation, and competitively binding to BTN3A1, Vγ9Vδ2 T cells amplified from cervical cancer (CC) patients can synergize with αβ T cells to exert anti‐CC function both in vitro and in vivo.
Min Wu, Jian Liu, Liting Liu, Yifan Yang, Hong Liu, Long Yu, Haihong Zeng, Shuo Yuan, Ruiyi Xu, Hangyu Liu, Han Jiang, Shen Qu, Liming Wang, Ying Chen, Jingyu Wang, Yuwei Zhang, Shan He, Ling Feng, Junyan Han, Wanjiang Zeng, Hui Wang, Yafei Huang   +21 more
wiley   +1 more source

Can viral load predict a symptomatic congenital CMV infection? A systematic review and meta-analysis. [PDF]

Eur J Pediatr
Salomè S, Gammella R, Coppola C, Dolce P, Capasso L, Blázquez-Gamero D, Raimondi F.   +6 more
europepmc   +1 more source

Comparison of Quantitations of Viral Load in Varicella and Zoster [PDF]

, 2000
Hiroshi Kimura, Shinji Kido, Takao Ozaki, Naoko Tanaka, Yoshinori Ito, Richard K. Williams, Tsuneo Morishima   +6 more
openalex   +1 more source

Blockade of ZMIZ1‐GATA4 Axis Regulation Restores Youthfulness to Aged Cartilage

Advanced Science, EarlyView.
The blockade of ZMIZ1‐GATA axis can be an effective therapeutic approach for treating OA. Functional inhibition of the ZMIZ1‐GATA axis through K‐7174 has the effect of suppressing cartilage damage and cellular senescence at the chondrocyte and cartilage tissue levels.
Jiho Nam, Hyunmin Woo, Jihye Yang, Seok Jung Kim, Kwang Pyo Lee, Ji Hoon Yu, Tae Joo Park, Seong‐il Eyun, Siyoung Yang   +8 more
wiley   +1 more source

Development of machine learning algorithms to predict viral load suppression among HIV patients in Conakry (Guinea). [PDF]

Front Artif Intell
Yehadji D, Gray G, Vicente CA, Isaakidis P, Diallo A, Kamano SA, Diallo TS.   +6 more
europepmc   +1 more source

Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population

, 2000
David R. Bangsberg, Frederick Hecht, Edwin D. Charlebois, Andrew Zolopa, Mark Holodniy, Lewis B. Sheiner, Joshua D. Bamberger, Margaret A. Chesney, Andrew R. Moss   +8 more
openalex   +1 more source

Sustained Vaccine Exposure Elicits More Rapid, Consistent, and Broad Humoral Immune Responses to Multivalent Influenza Vaccines

Advanced Science, EarlyView.
This work presents an injectable polymer‐nanoparticle hydrogel depot platform for delivering multivalent influenza vaccines which induces stronger and more durable immune responses. The technology provides broader protection, including against heterologous and potential pandemic strains (H5N1, H7N9, H9N2), and enhances the effectiveness of commercial ...
Olivia M. Saouaf, Ben S. Ou, Ye Eun Song, Joshua J. Carter, Jerry Yan, Carolyn K. Jons, Christopher O. Barnes, Eric A. Appel   +7 more
wiley   +1 more source