ddPCR: a more accurate tool for SARS-CoV-2 detection in low viral load specimens
Emerging Microbes and Infections, 2020 Quantitative real time PCR (RT-PCR) is widely used as the gold standard for clinical detection of SARS-CoV-2. However, due to the low viral load specimens and the limitations of RT-PCR, significant numbers of false negative reports are inevitable, which ...
T. Suo +22 more
semanticscholar +1 more source
Benefit of viral load testing for confirmation of immunological failure in HIV patients treated in rural Malawi. [PDF]
, 2011 Objective Viral load testing is used in the HIV programme of Chiradzulu, Malawi, to confirm the diagnosis of immunological failure to prevent unnecessary switching to second-line therapy.
Badri +14 more
core +2 more sources
SARS-CoV-2 viral load predicts COVID-19 mortality
The Lancet Respiratory Medicine, 2020 The need for reliable and widely available SARS-CoV-2 testing is well recognized, but it will be equally necessary to develop quantitative methods that determine viral load in order to guide patient triage and medical decision making. We are the first to
E. Pujadas +9 more
semanticscholar +1 more source
Suppression of HIV in the first 12 months of antiretroviral therapy: a comparative analysis of dolutegravir- and efavirenz-based regimens [PDF]
Einstein (São Paulo), 2023 Objective To compare viral suppression in treatment-naïve adults starting antiretroviral therapy with dolutegravir (50mg)- and efavirenz (600mg)-based regimens.
Gabriella Jomara da Silva +3 more
doaj +1 more source
Viral dynamics during structured treatment interruptions of chronic human immunodeficiency virus type 1 infection [PDF]
, 2002 Although antiviral agents which block human immunodeficiency virus (HIV) replication can result in long-term suppression of viral loads to undetectable levels in plasma, long-term therapy fails to eradicate virus, which generally rebounds after a single ...
Clotet, B +4 more
core +2 more sources
An analysis of SARS-CoV-2 viral load by patient age
medRxiv, 2020 As children are under-represented in current studies aiming to analyse transmission of SARS-coronavirus 2 (SARS-CoV-2), their contribution to transmission is unclear.
T. Jones +9 more
semanticscholar +1 more source
Quantifying the relationship between SARS-CoV-2 viral load and infectiousness
medRxiv, 2021 The relationship between SARS-CoV-2 viral load and infectiousness is not known. Using data from a prospective cohort of index cases and high-risk contact, we reconstructed by modelling the viral load at the time of contact and the probability of ...
Aurélien Marc +7 more
semanticscholar +1 more source
New Scientist, 2020 We don't yet know if being exposed to more coronavirus particles leads to more severe covid-19 symptoms, reports Linda Geddes.
openaire +2 more sources
HIV-1 viral load monitoring: an opportunity to reinforce treatment adherence in a resource-limited setting in Thailand. [PDF]
, 2008 This paper describes a program to increase patients' treatment literacy regarding viral load (VL) monitoring through patient education materials and a counseling protocol, implemented by peer counselors, in order to reinforce adherence to first-line ...
A. Kace Keiluhu +24 more
core +1 more source
Viral load and contact heterogeneity predict SARS-CoV-2 transmission and super-spreading events
eLife, 2021 SARS-CoV-2 is difficult to contain because many transmissions occur during pre-symptomatic infection. Unlike influenza, most SARS-CoV-2-infected people do not transmit while a small percentage infect large numbers of people.
Ashish Goyal +4 more
semanticscholar +1 more source