Results 41 to 50 of about 463,872 (305)

The effect of anthelmintic treatment during pregnancy on HIV plasma viral load: results from a randomized, double-blind, placebo-controlled trial in Uganda. [PDF]

, 2012
BACKGROUND: To investigate the effect of helminth infections and their treatment during pregnancy on HIV load, we conducted a 2 × 2 factorial randomized controlled trial of albendazole versus placebo and praziquantel versus placebo in pregnant women in ...
Elliott, Alison M, Kaleebu, Pontiano, Kizito, Dennison, Kyosiimire-Lugemwa, Jacqueline, Lule, Swaib, Muhangi, Lawrence, Muwanga, Moses, Nkurunziza, Peter, Webb, Emily L   +8 more
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Predictors of HIV Viral Load Suppression After Enhanced Adherence Counseling, Nekemte, Ethiopia

Journal of Epidemiology and Global Health
Background Enhanced adherence counseling refers to the counseling intervention for Human Immunodeficiency Virus (HIV) patients with an elevated viral load result, a viral load of > 1000 copies/ml, on a routine or need-based viral load test.
Yohannis Mosisa, Adisu Ewunetu, Kitesa Biresa Duftu, Bayise Biru, Debelo Diriba, Adisu Tafari Shama, Melese Lemi, Getahun Fetensa, Bikila Regassa Feyisa   +8 more
doaj   +1 more source

Viral Loads in Clinical Specimens and SARS Manifestations

Emerging Infectious Diseases, 2004
A retrospective viral load study was performed on clinical specimens from154 patients with laboratory-confirmed severe acute respiratory syndrome (SARS), prospectively collected during patients’ illness.
I.F.N. Hung, V.C.C. Cheng, A.K.L. Wu, B.S.F. Tang, K.H. Chan, C.M. Chu, M.M.L. Wong, W.T. Hui, L.L.M. Poon, D.M.W. Tse, K.S. Chan, P.C.Y. Woo, S.K.P. Lau, J.S.M. Peiris, K.Y. Yuen   +14 more
doaj   +1 more source

Two-year follow-up of macaques developing intermittent control of the human immunodeficiency virus homolog simian immunodeficiency virus SIVmac251 in the chronic phase of infection [PDF]

, 2015
Off-therapy control of viremia by HIV-infected individuals has been associated with two likely players: a restricted viral reservoir and an efficient cell-mediated immune response.
Arts, Eric, Biffoni, Mauro, Chung, Hye Kyung, Farrell, Nicholas, Labranche, Celia, Lewis, Mark G., Montefiori, David, Nickel, Gabrielle, Pal, Ranajit, PALAMARA, ANNA TERESA, Robert Guroff, Marjorie, Sacha, Jonah B., Savarino, Andrea, Shytaj, Iart Luca, Vargas Inchaustegui, Diego   +14 more
core   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Use of multi-trait and random regression models to identify genetic variation in tolerance to porcine reproductive and respiratory syndrome virus

Genetics Selection Evolution, 2017
Background A host can adopt two response strategies to infection: resistance (reduce pathogen load) and tolerance (minimize impact of infection on performance).
Graham Lough, Hamed Rashidi, Ilias Kyriazakis, Jack C. M. Dekkers, Andrew Hess, Melanie Hess, Nader Deeb, Antti Kause, Joan K. Lunney, Raymond R. R. Rowland, Han A. Mulder, Andrea Doeschl-Wilson   +11 more
doaj   +1 more source

Natural selection favoring more transmissible HIV detected in United States molecular transmission network. [PDF]

, 2019
HIV molecular epidemiology can identify clusters of individuals with elevated rates of HIV transmission. These variable transmission rates are primarily driven by host risk behavior; however, the effect of viral traits on variable transmission rates is ...
Campbell, Ellsworth, Heneine, Walid, Johnson, Jeffrey A, Oster, Alexandra M, Panneer, Nivedha, Saduvala, Neeraja, Switzer, William M, Wertheim, Joel O, Zhang, Chenhua   +8 more
core  

CD4 cell count and the risk of AIDS or death in HIV-Infected adults on combination antiretroviral therapy with a suppressed viral load: a longitudinal cohort study from COHERE. [PDF]

, 2012
BACKGROUND: Most adults infected with HIV achieve viral suppression within a year of starting combination antiretroviral therapy (cART). It is important to understand the risk of AIDS events or death for patients with a suppressed viral load.
A. Antinori, A. Antoniadou, A. Castagna, A. Castagna, A. Cozzi-Lepri, A. D’, A. Mocroft, A. Mocroft, A. Mocroft, A. Noguera-Julian, A. Phillips, A. Rauch, A. Scherrer, B. Gazzard, B. Ledergerber, C. Colin, C. Leport, C. Lewden, C. Mussini, C. Mussini, C. Sabin, C. Sabin, C. Smit, C. Stephan, C. Stephan, C. Thorne, C. Thorne, C. Torti, C. Torti, C. Torti, D. Costagliola, D. Gibb, D. Haerry, E. Girardi, F. Dabis, F. de Wolf, F. Engsig, F. Gutierrez, F. Raffi, G. Chene, G. Fatkenheuer, G. Touloumi, H. Bucher, H. Bucher, H. Bucher, H. Furrer, H. Furrer, H. Furrer, I. Weller, J. Bohlius, J. Casabona, J. Casabona, J. Del Amo, J. Ghosn, J. Ghosn, J. Grarup, J. Kjaer, J. Miro, J. Munoz, J. Ramos, J. Reekie, J. Sterne, J. Warszawski, J.M. Miro, L. Galli, L. Meyer, L. Meyer, L. Meyer, L. Wittkop, M. Battegay, M. Battegay, M. Dorrucci, M. Egger, M. Fisher, M. Garrido, M. Paulsen, M. Prins, M. Prins, M. Psichogiou, M. Puoti, M. Sharland, M. Sharland, M.M. Krause, N. Brockmeyer, N. Obel, N. Obel, N. Obel, O. Kirk, O. Kirk, O. Kirk, O. Kirk, O. Lambotte, P. Morlat, P. Reiss, P. Reiss, P. Reiss, P. Tookey, R. Lodwick, R. Paredes, R. Teira, R. Thiebaut, R. Zangerle, R. Zangerle, R.Teira, S. Ayayi, S. De Wit, S. Grabar, S. Matheron, S. Perez-Hoyos, T. Goetghebuer, V. Bouteloup, V. Le Moing, V. von Wyl, Y. Young   +113 more
core   +6 more sources

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

FEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke, Nils Alexander Lakomek, Georg Groth   +2 more
wiley   +1 more source