Results 41 to 50 of about 3,717,929 (382)

Switching to second-line antiretroviral therapy in resource-limited settings: comparison of programmes with and without viral load monitoring. [PDF]

, 2009
In high-income countries, viral load is routinely measured to detect failure of antiretroviral therapy (ART) and guide switching to second-line ART. Viral load monitoring is not generally available in resource-limited settings. We examined switching from
Boulle, A, Braitstein, P, Brinkhof, Martin, Calmy, A, Dabis, F, Egger, Matthias, Jahn, A, Keiser, O, Keiser, Olivia, Kumarasamy, N, Lüthy, R, MacPhail, P, Nash, D, Pujades-Rodriguez, M, Schechter, M, Sprinz, E, Tuboi, S, Tweya, H, Wood, R   +18 more
core   +3 more sources

Clinical Significance of a High SARS-CoV-2 Viral Load in the Saliva

Journal of Korean medical science, 2020
Background Patients with coronavirus disease 2019 (COVID-19) can unknowingly spread the virus to several people during the early subclinical period. Methods We evaluated the viral dynamics in various body fluid specimens, such as nasopharyngeal swab ...
J. Yoon, Jung Yoon, J. Song, Soo-Young Yoon, C. Lim, Hye-Yeong Seong, J. Noh, H. Cheong, W. Kim   +8 more
semanticscholar   +1 more source

SARS-CoV-2 infectivity by viral load, S gene variants and demographic factors and the utility of lateral flow devices to prevent transmission

medRxiv, 2021
Background: How SARS-CoV-2 infectivity varies with viral load is incompletely understood. Whether rapid point-of-care antigen lateral flow devices (LFDs) detect most potential transmission sources despite imperfect sensitivity is unknown.
Lennard W. Lee, Stefan Rozmanowski, M. Pang, A. Charlett, C. Anderson, G. Hughes, Matthew Barnard, L. Peto, R. Vipond, Alex C. Sienkiewicz, S. Hopkins, J. Bell, D. Crook, N. Gent, A. Walker, T. Peto, D. Eyre   +16 more
semanticscholar   +1 more source

The effect of anthelmintic treatment during pregnancy on HIV plasma viral load: results from a randomized, double-blind, placebo-controlled trial in Uganda. [PDF]

, 2012
BACKGROUND: To investigate the effect of helminth infections and their treatment during pregnancy on HIV load, we conducted a 2 × 2 factorial randomized controlled trial of albendazole versus placebo and praziquantel versus placebo in pregnant women in ...
Elliott, Alison M, Kaleebu, Pontiano, Kizito, Dennison, Kyosiimire-Lugemwa, Jacqueline, Lule, Swaib, Muhangi, Lawrence, Muwanga, Moses, Nkurunziza, Peter, Webb, Emily L   +8 more
core   +1 more source

Kinetics of viral load and antibody response in relation to COVID-19 severity.

Journal of Clinical Investigation, 2020
The SARS-CoV-2 is the causative agent for COVID-19 pneumonia. Little is known about the kinetics, tissue distribution, cross-reactivity and neutralization antibody response in COVID-19 patients.
Yanqun Wang, Lu Zhang, L. Sang, F. Ye, Shicong Ruan, Bei Zhong, T. Song, A. Alshukairi, Rongchang Chen, Zhaoyong Zhang, Mian Gan, Airu Zhu, Yongbo Huang, L. Luo, C. K. Mok, Manal M. Al Gethamy, H. Tan, Zhengtu Li, Xiaofang Huang, Fang Li, Jing Sun, Yanjun Zhang, Liyan Wen, Yuming Li, Zhaoming Chen, Z. Zhuang, Jianfen Zhuo, Chunke Chen, Lijun Kuang, Junxiang Wang, Huibin Lv, Yongliang Jiang, Min Li, Yimin Lin, Ying Deng, Lan-fong Tang, Jieling Liang, Jicheng Huang, S. Perlman, N. Zhong, Jingxian Zhao, J. S. Malik Peiris, Yimin Li, Jincun Zhao   +43 more
semanticscholar   +1 more source

Analysis of influencing factors of viral load in patients with high-risk human papillomavirus

Virology Journal, 2021
Background High-risk human papillomavirus (HR-HPV) load is thought to be influenced by many factors, and the relationship between viral load and the degree of cervical lesion is controversial.
Xuerong Lu, Tiantian Wang, Youzhong Zhang, Yuzhen Liu   +3 more
doaj   +1 more source

Initiation of HIV therapy [PDF]

, 2010
In this paper, we numerically show that the dynamics of the HIV system is sensitive to both the initial condition and the system parameters. These phenomena imply that the system is chaotic and exhibits a bifurcation behavior.
BINGO WING-KUEN LING, CHARLOTTE YUK-FAN HO, Nowak M. A.   +2 more
core   +1 more source

Cycle threshold values in RT‐PCR to determine dynamics of SARS‐CoV‐2 viral load: An approach to reduce the isolation period for COVID‐19 patients

Journal of Medical Virology, 2021
Severe acute respiratory syndrome coronavirus (SARS‐CoV‐2) has affected all inhabited continents, and India is currently experiencing a devastating second wave of coronavirus disease‐2019 (COVID‐19).
C. Aranha, V. Patel, V. Bhor, Dimpu Gogoi   +3 more
semanticscholar   +1 more source

Reduction of SARS-CoV-2 viral load in saliva after rinsing with mouthwashes containing cetylpyridinium chloride: a randomized clinical study [PDF]

PeerJ, 2023
Background Symptomatic patients with COVID-19 typically have a high SARS-CoV-2 viral load in their saliva. Procedures to reduce the viral load in their oral cavity are important for mitigating the viral transmission.
Leticia M. Bezinelli, Luciana Corrêa, Stephany Beyerstedt, Marcella L. Franco, Érika B. Rangel, Carlos Guillermo Benítez, Nelson Hamerschlak, João R.R. Pinho, Debora Heller, Fernanda P. Eduardo   +9 more
doaj   +2 more sources

Viral load and neuropathology in the SIV model [PDF]

Journal of Neurovirology, 1999
To investigate neuropathological processes involved in HIV infection, a longitudinal analysis of central nervous system (CNS) changes was performed using the SIV-infected macaque model. Five animals were studied during the early phase and 13 during the asymptomatic and symptomatic phases.
Boche, D., Khatissian, E., Gray, F., Falanga, P., Montagnier, L., Hurtrel, B.   +5 more
openaire   +3 more sources