Results 181 to 190 of about 131,769 (294)

Predictors of longitudinal viral load suppression among adults receiving first line antiretroviral therapy in Central Ethiopia. [PDF]

Sci Rep
Suwanbamrung C, Abraham A, Asheber M, Jaldo MM, Yakob T.   +4 more
europepmc   +1 more source

1566Factors Associated with 10 Years of Continuous HIV Viral Load Suppression on HAART [PDF]

Open Forum Infectious Diseases, 2014
Bello, Kathryn, Mesner, Octavio, O'bryan, Thomas, Lalani, Tahaniyat, Ganesan, Anuradha, Agan, Brian, Okulicz, Jason   +6 more
openaire   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

HIV viral load suppression and associated factors among PLHIV with non-communicable diseases in Uganda's Teso Region: a cross-sectional retrospective study. [PDF]

AIDS Res Ther
Oryokot B, Ssentongo SM, Oluka AI, Otaala T, Sairo H, Muniina A, Olweny DJ, Bakashaba B, Andres AR.   +8 more
europepmc   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

Determinants associated with non-adherence to antiretroviral therapy (ART) and viral load suppression in PLHIV in Meta, Colombia. [PDF]

J Public Health (Oxf)
Daniel CJ, Cristina PN, Jorge OB, Cesar GB, Valeria DAS, Sebastián AZ, Norton PG, Nancy C, Liliana BV, Alberto SPO, Marcela MRL.   +10 more
europepmc   +1 more source

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome

Advanced Science, EarlyView.
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel, Anna Meurer, Badeel Kh. Q. Zaghla, Bilge Atay, Daniel Steiert, Luca V. Hummel, Konstandina Isaakidis, Chuanbing Zang, Michael Korenkov, Marlon Schielin, Schayan Yousefian, Shima Mecklenbräuker, Marieluise Kirchner, Simon Haas, Antonia Busse, Philipp Mertins, Stefan Müller, Matthias Wirth, Martin G. Klatt, Ulrich Keller   +19 more
wiley   +1 more source

Viral Load Suppression After Intensive Adherence Counselling Among Previously Non-Suppressed Adolescents and Young People with HIV in East-Central Uganda. [PDF]

HIV AIDS (Auckl)
Ejalu DL, Okello PS, Puleh SS, Nangendo J, Izudi J, Bakeera-Kitaka S, Katamba A, Katahoire AR, Kalyango JN, Cattamanchi A, Semitala FC, Kamya MR.   +11 more
europepmc   +1 more source

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

Advanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu, Yajie Zhang, Yushi Tang, Hongli Hu, Ying Zhang, Junwen Xue, Hao Wang, Yecheng Wang, Chunfeng Liu, Jia Jia, Jian Cheng, Yongjun Cao   +11 more
wiley   +1 more source

A qualitative exploration of psychosocial determinants influencing viral load suppression among adolescents living with HIV: Application of social action theory. [PDF]

Health SA
Thosago MJ, Lowane MP.
europepmc   +1 more source