Results 21 to 30 of about 131,769 (294)

Risk of sexual transmission of HIV in the context of viral load suppression. [PDF]

Can Commun Dis Rep, 2023
In 2018, the Public Health Agency of Canada (PHAC) published a systematic review to calculate the risk of sexual transmission of human immunodeficiency virus (HIV) in the context of antiretroviral therapy (ART). In 2022, PHAC commissioned the Canadian Agency for Drugs and Technologies in Health (CADTH) to conduct a rapid review of evidence published ...
Djiadeu P, Begum H, Sabourin S, Gadient S, Archibald C, LeBlanc MA, Chittle A, Fleurant A, Cox J.   +8 more
europepmc   +3 more sources

Viral Load Suppression after Enhanced Adherence Counseling and Its Predictors among High Viral Load HIV Seropositive People in North Wollo Zone Public Hospitals, Northeast Ethiopia, 2019: Retrospective Cohort Study

AIDS Research and Treatment, 2020
Background. The World Health Organization currently encourages enhanced adherence counseling for human immunodeficiency virus (HIV) seropositive people with a high viral load count before a treatment switch to the second-line regimen, yet little is known
Gedefaw Diress, Samuel Dagne, Birhan Alemnew, Seteamlak Adane, Amanuel Addisu   +4 more
doaj   +1 more source

Determinants of viral suppression among adolescents on antiretroviral treatment in Ehlanzeni district, South Africa: a cross-sectional analysis

AIDS Research and Therapy, 2021
Background Achieving undetectable viral load is crucial for the reduction of HIV transmissions, AIDS-related illnesses and death. Adolescents (10 to19 years) living with HIV (ALHIV) on antiretroviral treatment (ART) have worse treatment adherence and ...
Emeka F. Okonji, Brian van Wyk, Ferdinand C. Mukumbang, Gail D. Hughes   +3 more
doaj   +1 more source

Intact HIV DNA decays in children with and without complete viral load suppression. [PDF]

PLoS Pathog
To inform cure in children living with HIV (CWH), we elucidated the dynamics and mechanisms underlying HIV persistence during antiretroviral therapy (ART). In 120 Kenyan CWH who initiated ART between 1-12 months of age, 55 had durable viral load suppression, and 65 experienced ART interruptions. We measured plasma HIV RNA levels, CD4+ T cell count, and
Reeves DB, Litchford M, Fish CS, Farrell-Sherman A, Poindexter M, Ahmed N, Cassidy NAJ, Neary J, Wamalwa D, Langat A, Chebet D, Moraa H, Antar AAR, Slyker J, Benki-Nugent S, Cohn LB, Schiffer JT, Overbaugh J, John-Stewart G, Lehman DA.   +19 more
europepmc   +4 more sources

Population levels and geographical distribution of HIV RNA in rural Ugandan and Kenyan communities, including serodiscordant couples: a cross-sectional analysis. [PDF]

, 2017
BackgroundAs sub-Saharan Africa transitions to a new era of universal antiretroviral therapy (ART), up-to-date assessments of population-level HIV RNA suppression are needed to inform interventions to optimise ART delivery.
Black, Doug, Bukusi, Elizabeth A, Byonanebye, Dathan M, Chamie, Gabriel, Charlebois, Edwin D, Clark, Tamara D, Cohen, Craig R, Havlir, Diane V, Jain, Vivek, Kabami, Jane, Kamya, Moses R, Kwarisiima, Dalsone, Ladai, Andras, Liegler, Teri, Petersen, Maya L, Plenty, Albert, Sang, Norton, SEARCH Collaboration, Ssemmondo, Emmanuel   +18 more
core   +1 more source

Optimizing viral load suppression in Kenyan children on antiretroviral therapy (Opt4Kids)

Contemporary Clinical Trials Communications, 2020
As many as 40% of the 1 million children living with HIV (CLHIV) receiving antiretroviral treatment (ART) in resource limited settings have not achieved viral suppression (VS). Kenya has a large burden of pediatric HIV with nearly 140,000 CLHIV. Feasible, scalable, and cost-effective approaches to ensure VS in CLHIV are urgently needed.
Rena C. Patel, Patrick Oyaro, Beryne Odeny, Irene Mukui, Katherine K. Thomas, Monisha Sharma, James Wagude, Eunice Kinywa, Frederick Oluoch, Francesca Odhiambo, Boaz Oyaro, Grace C. John-Stewart, Lisa L. Abuogi   +12 more
openaire   +3 more sources

Brachial amyotrophic diplegia in the setting of complete HIV viral load suppression [PDF]

BMJ Case Reports, 2012
Brachial amyotrophic diplegia (BAD) is a rare segmental form of motor neuron disease which presents with asymmetric lower motor neuron weakness largely confined to the upper extremities (UE). In the case being reported, a 62-year-old gentleman on antiretroviral treatment since 1993, presented with left-arm weakness in 2007 that quickly progressed to ...
David, Cachia, Saef, Izzy, Carolina, Ionete, Johnny, Salameh   +3 more
openaire   +2 more sources

A Retrospective Survey of HIV Drug Resistance Among Patients 1 Year After Initiation of Antiretroviral Therapy at 4 Clinics in Malawi [PDF]

, 2012
In 2004, Malawi began scaling up its national antiretroviral therapy (ART) program. Because of limited treatment options, population-level surveillance of acquired human immunodeficiency virus drug resistance (HIVDR) is critical to ensuring long-term ...
Anthony Harries, Barth, Ben Chilima, Bennett, Bennett, Bethany L. Hedt, Carol Porter, Coetzee, Diane E. Bennett, Eddie Limbambala, Erik Schouten, George Bello, Hedt, Hosseinipour, Joep J. van Oosterhout, Johannessen, John Aberle-Grasse, Jordan, Kamoto, Kamya, Kouanfack, Koyalta, Kundai Moyo, Liu, Maldonado, Marcelin, Marconi, Michael R. Jordan, Mina Hosseinipour, Ministry of Health, Moses Massaquoi, Nellie Wadonda-Kabondo, Nzeyimana, Oyugi, Pillay, Puthanakit, Ralf Weigel, Storn Kabuluzi, Sungkanuparph, Wallis, Yu   +40 more
core   +2 more sources

SUPPRESSION OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 VIRAL LOAD DURING ACUTE MEASLES [PDF]

Pediatric Infectious Disease Journal, 2009
Acute measles virus infection can result in a transient decrease in plasma human immunodeficiency virus type 1 (HIV-1) RNA loads. We report the kinetics of plasma HIV-1 RNA loads in 2 Zambian children with confirmed and probable measles, and show that the decline in viral load is of similar magnitude to the first-phase decay rate after initiation of ...
William J, Moss, Susana, Scott, Zaza, Ndhlovu, Mwaka, Monze, Felicity T, Cutts, Thomas C, Quinn, Diane E, Griffin   +6 more
openaire   +2 more sources

Predicting virological decay in patients starting combination antiretroviral therapy. [PDF]

, 2016
OBJECTIVE: Model trajectories of viral load measurements from time of starting combination antiretroviral therapy (cART), and use the model to predict whether patients will achieve suppressed viral load (≤200 copies/ml) within 6-months of starting cART ...
Anastos, Andrade, Cescon, Cozzi Lepri, Diggle, Glas, Grabar, Gunthard, Hartzell, Haubrich, Herz, Ho, Knobel, Kuritzkes, Marconi, McGinnis, Mittler, Mueller, Notermans, Pence, Perelson, Polis, Riddler, Royston, Rubin, Simoni, Smith, Spector, Taylor, Taylor, Taylor, Tucker, Wei, Weintrob, Weintrob, Williams, Wu, Wu, Wu, Wu, Yamashita   +40 more
core   +4 more sources