Results 1 to 10 of about 259,105 (298)

A comparative analysis of viral matrix proteins using disorder predictors [PDF]

Virology Journal, 2008
Background A previous study (Goh G.K.-M., Dunker A.K., Uversky V.N. (2008) Protein intrinsic disorder toolbox for comparative analysis of viral proteins. BMC Genomics. 9 (Suppl.
Dunker A Keith, Goh Gerard, Uversky Vladimir N   +2 more
doaj   +4 more sources

Matrix protein 1 (M1) of influenza A virus: structural and functional insights [PDF]

Emerging Microbes and Infections
Enveloped viruses rely on matrix proteins for structural integrity and lifecycle progression. Matrix protein 1 (M1) is the most abundant structural protein of influenza A virus (IAV), playing a multifaceted role in viral uncoating, polymerase activity ...
Yanting Zhu, Yixue Sun, Xiaoyu Deng, Peige Cao, Siqi Li, Huilin Yu, Shouzhi Sheng, Yanlong Cong   +7 more
doaj   +2 more sources

Annexin A2 stabilizes the endoplasmic reticulum and actin cytoskeleton and influences the formation of reovirus factories [PDF]

Journal of Virology
Early in infection, mammalian orthoreoviruses (reoviruses) build neo-organelles called viral factories (VFs). These structures incorporate fragments of endoplasmic reticulum (ER) and serve as sites of viral genome replication and particle assembly.
Raquel Tenorio, Gwen M. Taylor, Ana Cayuela, C. O. S. Sorzano, Isabel Fernández de Castro, Sara Y. Fernández-Sánchez, Alexa N. Roth, Xayathed Somoulay, Gavin S. Treadaway, Terence S. Dermody, Cristina Risco   +10 more
doaj   +2 more sources

Uncovering human kinase substrates in nipah proteome [PDF]

Frontiers in Bioinformatics
Nipah virus (NiV) is a zoonotic pathogen that causes recurrent outbreaks with considerable implications for public health. Viruses engage host kinases to phosphorylate viral proteins, aiding replication and host disruption.
Vineetha Shaji, Vineetha Shaji, Akash Anil, Ayisha A. Jabbar, Althaf Mahin, Althaf Mahin, Ahmad Rafi, Amjesh Revikumar, Sowmya Soman, Ganesh Prasad, Sneha M. Pinto, Yashwanth Subbannayya, Yashwanth Subbannayya, Abhithaj Jayanandan, Rajesh Raju   +14 more
doaj   +2 more sources

The Interactions of Viral Matrix Proteins with Membranes [PDF]

Biophysical Journal, 2011
Matrix proteins form the main structure of an enveloped virus, connecting the nucleocapsid to the phospholipid membrane. We have studied the M1 proteins from HRSV and Influenza A to determine their structural characteristics and the nature of their lipid binding.
James A. Freeth, John M. Sanderson, Paul Yeo   +2 more
openalex   +2 more sources

Restriction of Viral Replication by Mutation of the Influenza Virus Matrix Protein [PDF]

Journal of Virology, 2002
ABSTRACT The matrix protein (M1) of influenza virus plays an essential role in viral assembly and has a variety of functions, including association with influenza virus ribonucleoprotein (RNP). Our previous studies show that the association of M1 with viral RNA and nucleoprotein not only promotes formation of helical RNP but also is required ...
Teresa Liu, Zhiping Ye
openalex   +3 more sources

Interaction of Human Parainfluenza Virus Type 3 Nucleoprotein with Matrix Protein Mediates Internal Viral Protein Assembly [PDF]

Journal of Virology, 2015
ABSTRACT Human parainfluenza virus type 3 (HPIV3) belongs to the Paramyxoviridae family. Its three internal viral proteins, the nucleoprotein (N), the phosphoprotein (P), and the polymerase (L), form the ribonucleoprotein (RNP) complex, which encapsidates the viral genome and associates with the matrix ...
Guangyuan Zhang, Yi Zhong, Yali Qin, Mingzhou Chen   +3 more
openalex   +3 more sources

Chicken bromodomain-containing protein 2 interacts with the Newcastle disease virus matrix protein and promotes viral replication [PDF]

Veterinary Research, 2020
AbstractBromodomain-containing protein 2 (BRD2) is a nucleus-localized serine-threonine kinase that plays pivotal roles in the transcriptional control of diverse genes. In our previous study, the chicken BRD2 (chBRD2) protein was found to interact with the Newcastle disease virus (NDV) matrix (M) protein using a yeast two-hybrid screening system, but ...
Zhiqiang Duan, Yifan Han, Lei Zhou, Chao Yuan, Yanbi Wang, Caiqin Zhao, Hong Tang, Jiaqi Chen   +7 more
openalex   +5 more sources

The Matrix Protein of Measles Virus Regulates Viral RNA Synthesis and Assembly by Interacting with the Nucleocapsid Protein [PDF]

Journal of Virology, 2009
ABSTRACT The genome of measles virus (MV) is encapsidated by the nucleocapsid (N) protein and associates with RNA-dependent RNA polymerase to form the ribonucleoprotein complex. The matrix (M) protein is believed to play an important role in MV assembly by linking the ribonucleoprotein complex with envelope glycoproteins.
Masaharu Iwasaki, Makoto Takeda, Yuta Shirogane, Yuichiro Nakatsu, Takanori Nakamura, Yusuke Yanagi   +5 more
  +6 more sources

Paramyxovirus matrix protein redirects METTL3 for dual regulation of viral replication and immune evasion. [PDF]

PLoS Pathog
Okura T, Nakai Y, Kameya T, Mizukoshi F, Okura H, Kakizaki M, Kato F, Matsumoto Y, Nakatsu Y, Takeuchi K, Kimura H, Takeda M, Otsuki N, Shirato K, Hasegawa H, Ryo A.   +15 more
europepmc   +2 more sources