Results 21 to 30 of about 664,008 (371)
The Matrix Protein of Measles Virus Regulates Viral RNA Synthesis and Assembly by Interacting with the Nucleocapsid Protein [PDF]
Journal of Virology, 2009 ABSTRACT The genome of measles virus (MV) is encapsidated by the nucleocapsid (N) protein and associates with RNA-dependent RNA polymerase to form the ribonucleoprotein complex. The matrix (M) protein is believed to play an important role in MV assembly by linking the ribonucleoprotein complex with envelope glycoproteins.
Masaharu Iwasaki +5 more
+9 more sources
Characterization of a Slow‐Migrating Component of the Rabies Virus Matrix Protein Strongly Associated with the Viral Glycoprotein [PDF]
Microbiology and Immunology, 2003 AbstractWe investigated multiple forms of rabies virus matrix (M) protein. Under non‐reducing electrophoretic conditions, we detected, in addition to major bands of monomer forms (23‐ and 24‐kDa) of M protein, an M antigen‐positive slow‐migrating minor band (about 54 kDa) in both the virion and infected cells.
Tomomi Nakahara +6 more
openalex +4 more sources
Medical Immunology (Russia), 2023 The reproductive potential of both women and men is declining every year. Many factors contribute to the violation of the reproductive function – chemical, physical, mechanical, psychogenic, however, biological factors have the most pronounced effect on reproduction.
T. А. Nevezhkina +7 more
openalex +4 more sources
A Calcium-Fortified Viral Matrix Protein [PDF]
Structure, 2014 In this issue of Structure, Leyrat and colleagues provide the first structural analysis of the human metapneumovirus (HMPV) matrix protein, a key regulator of viral assembly. Though structurally similar to other matrix proteins, two calcium binding sites suggest intriguing differences in regulation.
Rebecca Ellis Dutch, Gaya K. Amarasinghe
openaire +3 more sources
Virology, 2003 The influenza virus copies its genomic RNA in the nuclei of host cells, but the viral particles are formed at the plasma membrane. Thus, the export of new genome from the nucleus into the cytoplasm is essential for viral production. Several viral proteins, such as nucleoprotein (NP) and RNA polymerases, synthesized in the cytoplasm, are imported into ...
A. Sakaguchi +4 more
openalex +4 more sources
The Deoptimization of Rabies Virus Matrix Protein Impacts Viral Transcription and Replication [PDF]
Viruses, 2019 Rabies virus (RABV) matrix (M) protein plays several important roles during RABV infection. Although previous studies have assessed the functions of M through gene rearrangements, this interferes with the position of other viral proteins. In this study, we attenuated M expression through deoptimizing its codon usage based on codon pair bias in RABV ...
Jun Luo +9 more
openaire +3 more sources
Efficient HIV-1 replication can occur in the absence of the viral matrix protein [PDF]
The EMBO Journal, 1998 Matrix (MA), a major structural protein of retroviruses, is thought to play a critical role in several steps of the HIV-1 replication cycle, including the plasma membrane targeting of Gag, the incorporation of envelope (Env) glycoproteins into nascent particles, and the nuclear import of the viral genome in non-dividing cells.
Heide Reil
openalex +4 more sources
ANP32B is a nuclear target of henipavirus M proteins. [PDF]
PLoS ONE, 2014 Membrane envelopment and budding of negative strand RNA viruses (NSVs) is mainly driven by viral matrix proteins (M). In addition, several M proteins are also known to be involved in host cell manipulation.
Anja Bauer +10 more
doaj +1 more source
cccDNA Maintenance in Chronic Hepatitis B – Targeting the Matrix of Viral Replication
Infection and Drug Resistance, 2020 Chronic hepatitis B is a numerically important cause of cirrhosis and hepatocellular carcinoma, despite an effective prophylactic vaccine and well-tolerated and effective oral antivirals.
M. Dandri, J. Petersen
semanticscholar +1 more source
The Matrix Protein of a Plant Rhabdovirus Mediates Superinfection Exclusion by Inhibiting Viral Transcription [PDF]
Journal of Virology, 2019 Superinfection exclusion (SIE) is a widespread phenomenon in which an established virus infection prevents reinfection by closely related viruses. Understanding the mechanisms governing SIE will not only advance our basic knowledge of virus infection cycles but may also lead to improved design of antiviral measures. Despite the significance of SIE, our
Andrew O. Jackson +5 more
openaire +4 more sources