Results 31 to 40 of about 259,105 (298)
The Human Respiratory Syncytial Virus Matrix Protein Is Required for Maturation of Viral Filaments [PDF]
Journal of Virology, 2012 ABSTRACT An experimental system was developed to generate infectious human respiratory syncytial virus (HRSV) lacking matrix (M) protein expression (M-null virus) from cDNA. The role of the M protein in virus assembly was then examined by infecting HEp-2 and Vero cells with the M-null virus and assessing the impact on infectious virus ...
Ruchira Mitra +4 more
openalex +4 more sources
Use of Aptamers as Diagnostics Tools and Antiviral Agents for Human Viruses
Pharmaceuticals, 2016 Appropriate diagnosis is the key factor for treatment of viral diseases. Time is the most important factor in rapidly developing and epidemiologically dangerous diseases, such as influenza, Ebola and SARS.
Víctor M. González +3 more
doaj +1 more source
Журнал инфектологии, 2020 Objective: isolation of coronavirus SARS-CoV-2 from clinical sample of patient with COVID-19 in Novosibirsk; obtaining a purified and inactivated viral antigen and study of its antigenic properties.
A. A. Chepurnov +9 more
doaj +1 more source
Scientific Reports, 2017 Polyhedra can encapsulate other proteins and have potential applications as protein stabilizers. The extremely stable polyhedra matrix may provide a platform for future engineered micro-crystal devices.
Zhong-Jian Guo +6 more
doaj +1 more source
Advances in Virology, 2011 Human respiratory syncytial virus (HRSV) is an enveloped RNA virus that assembles and buds from the plasma membrane of infected cells. The ribonucleoprotein complex (RNP) must associate with the viral matrix protein and glycoproteins to form newly ...
Melissa Batonick, Gail W. Wertz
doaj +1 more source
Microbiology Spectrum, 2023 The pathogenicity of a virus to a specific host species is an inerratic and describable ability of a virus to cause infection but is generally shaped by a variety of abiotic and biotic factors.
Huan Yu +6 more
doaj +1 more source
The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response. [PDF]
PLoS Pathogens, 2016 For efficient replication, viruses have developed mechanisms to evade innate immune responses, including the antiviral type-I interferon (IFN-I) system.
Preeti Bharaj +9 more
doaj +1 more source
Intracellular Transport of HIV-1 Matrix Protein Associated with Viral RNA
World Journal of AIDS, 2013 HIV-1 matrix protein (MA) is a multifunctional structural protein localized on N terminus of Gag precursor p55. MA participates in HIV-1 assembly as membranotropic part of Gag precursor as well as an individual protein spliced from Gag early in infection. MA is found in the nuclei of infected cells and in plasma membrane, the site of virus assembly, in
Anatoliy I. Gozhenko +4 more
openaire +2 more sources
Molecular Mechanism of Arenavirus Assembly and Budding
Viruses, 2012 Arenaviruses have a bisegmented negative-strand RNA genome, which encodes four viral proteins: GP and NP by the S segment and L and Z by the L segment. These four viral proteins possess multiple functions in infection, replication and release of progeny ...
Shuzo Urata, Jiro Yasuda
doaj +1 more source
Annexin A2 gene interacting with viral matrix protein to promote bovine ephemeral fever virus release [PDF]
Journal of Veterinary Science, 2020 Bovine ephemeral fever virus (BEFV) causes bovine ephemeral fever, which can produce considerable economic damage to the cattle industry. However, there is limited experimental evidence regarding the underlying mechanisms of BEFV. Annexin A2 (AnxA2) is a calcium and lipid-conjugated protein that binds phospholipids and the cytoskeleton in a Ca2 ...
Lihui Chen +4 more
openaire +2 more sources