Results 41 to 50 of about 664,008 (371)
Modulation of Host Immunity by Human Respiratory Syncytial Virus Virulence Factors: A Synergic Inhibition of Both Innate and Adaptive Immunity [PDF]
, 2017 Indexación: Web of Science; Scopus.The Human Respiratory Syncytial Virus (hRSV) is a major cause of acute lower respiratory tract infections (ARTIs) and high rates of hospitalizations in children and in the elderly worldwide.
Acevedo-Acevedo, O. +7 more
core +1 more source
Matrix protein Osteonectin (SPARC) reduces inflammation and mortality during viral myocarditis [PDF]
European Heart Journal, 2013 Rationale: Acute viral myocarditis (VM) is one of the leading causes of heart failure in young adults, lacking specific therapy. Osteonection (SPARC) is a non-structural matrix protein modulating cell-matrix interaction in the heart, and has been implicated in cardiac remodeling.
M. Rienks +6 more
openaire +2 more sources
International Journal of Infectious Diseases, 2023 Intro: Influenza A virus, a respiratory pathogen known to manipulate various cellular metabolic processes including glycolysis. Our earlier studies demonstrated the interaction of influenza A viral structural proteins; nucleoprotein and matrix protein ...
P. Goyal, M.S. Rajala
doaj
Use of Aptamers as Diagnostics Tools and Antiviral Agents for Human Viruses
Pharmaceuticals, 2016 Appropriate diagnosis is the key factor for treatment of viral diseases. Time is the most important factor in rapidly developing and epidemiologically dangerous diseases, such as influenza, Ebola and SARS.
Víctor M. González +3 more
doaj +1 more source
PLoS Pathogens, 2015 The paramyxovirus matrix (M) protein is a molecular scaffold required for viral morphogenesis and budding at the plasma membrane. Transient nuclear residence of some M proteins hints at non-structural roles.
Mickey Pentecost +10 more
semanticscholar +1 more source
A facile quantitative assay for viral particle genesis reveals cooperativity in virion assembly and saturation of an antiviral protein [PDF]
, 2012 Conventional assays of viral particle assembly and release are time consuming and laborious. We have developed an enzymatic virus-like particle (VLP) genesis assay that rapid and quantitative and is also versatile and applicable to diverse viruses ...
Capul +30 more
core +1 more source
Журнал инфектологии, 2020 Objective: isolation of coronavirus SARS-CoV-2 from clinical sample of patient with COVID-19 in Novosibirsk; obtaining a purified and inactivated viral antigen and study of its antigenic properties.
A. A. Chepurnov +9 more
doaj +1 more source
A Computational-Experimental Approach Identifies Mutations That Enhance Surface Expression of an Oseltamivir-Resistant Influenza Neuraminidase [PDF]
, 2011 The His274 → Tyr (H274Y) oseltamivir (Tamiflu) resistance mutation causes a substantial decrease in the total levels of surface-expressed neuraminidase protein and activity in early isolates of human seasonal H1N1 influenza, and in the swine-origin ...
Baltimore, David +2 more
core +11 more sources
Dissociation of Rabies Virus Matrix Protein Functions in Regulation of Viral RNA Synthesis and Virus Assembly [PDF]
Journal of Virology, 2003 ABSTRACT Recently, we have shown that the rabies virus (RV) matrix (M) protein regulates the balance of virus RNA synthesis by shifting synthesis activity from transcription to replication (S. Finke, R. Mueller-Waldeck, and K. K. Conzelmann, J. Gen. Virol. 84:1613-1621, 2003).
Stefan Finke, Karl‐Klaus Conzelmann
openalex +5 more sources
Advances in Virology, 2011 Human respiratory syncytial virus (HRSV) is an enveloped RNA virus that assembles and buds from the plasma membrane of infected cells. The ribonucleoprotein complex (RNP) must associate with the viral matrix protein and glycoproteins to form newly ...
Melissa Batonick, Gail W. Wertz
doaj +1 more source