Results 41 to 50 of about 259,105 (298)
mBio, 2020 Paramyxoviruses are negative-sense single-stranded RNA viruses that comprise many important human and animal pathogens, including human parainfluenza viruses.
Emmanuelle Genoyer +10 more
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Structural Modeling of Human Immunodeficiency Virus Proteins
Biomedical Engineering and Computational Biology, 2023 Human immunodeficiency virus (HIV) is an infectious virus that depletes the CD4 + T lymphocytes of the immune system and causes a chronic life-treating disease—acquired immunodeficiency syndrome (AIDS).
Amir Elalouf
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Virus Research, 2011 Chandipura virus (CV; genus Vesiculovirus, family Rhabdoviridae) is an emerging arbovirus, responsible for a number of outbreaks of severe viral encephalitis affecting children in India. A reverse genetics system has been constructed which allows recovery of infectious recombinant CV (rCV) entirely from cDNA.
Anthony C, Marriott, Crystal A, Hornsey
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Elucidating the Interacting Domains of Chandipura Virus Nucleocapsid Protein
Advances in Virology, 2013 The nucleocapsid (N) protein of Chandipura virus (CHPV) plays a crucial role in viral life cycle, besides being an important structural component of the virion through proper organization of its interactions with other viral proteins.
Kapila Kumar +8 more
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mSystems, 2019 Classified as a biosafety level 4 (BSL4) select agent, Nipah virus (NiV) is a deadly henipavirus in the Paramyxoviridae family, with a nearly 75% mortality rate in humans, underscoring its global and animal health importance.
Gunner P. Johnston +13 more
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Nucleocytoplasmic Shuttling of Influenza A Virus Proteins
Viruses, 2015 Influenza viruses transcribe and replicate their genomes in the nuclei of infected host cells. The viral ribonucleoprotein (vRNP) complex of influenza virus is the essential genetic unit of the virus.
Jing Li +3 more
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Deep sequencing of protease inhibitor resistant HIV patient isolates reveals patterns of correlated mutations in Gag and protease. [PDF]
PLoS Computational Biology, 2015 While the role of drug resistance mutations in HIV protease has been studied comprehensively, mutations in its substrate, Gag, have not been extensively cataloged.
William F Flynn +7 more
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Salinomycin Inhibits Influenza Virus Infection by Disrupting Endosomal Acidification and Viral Matrix Protein 2 Function [PDF]
Journal of Virology, 2018 Influenza virus is a main cause of viral respiratory infection in humans as well as animals, occasionally with high mortality. Circulation of influenza viruses resistant to the matrix protein 2 (M2) inhibitor, amantadine, is highly prevalent. Moreover, the frequency of detection of viruses resistant to the neuraminidase inhibitors, including ...
Yejin, Jang +8 more
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Function, Architecture, and Biogenesis of Reovirus Replication Neoorganelles
Viruses, 2019 Most viruses that replicate in the cytoplasm of host cells form neoorganelles that serve as sites of viral genome replication and particle assembly. These highly specialized structures concentrate viral proteins and nucleic acids, prevent the activation ...
Raquel Tenorio +6 more
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Phosphatidylserine clustering by the Ebola virus matrix protein is a critical step in viral budding
EMBO reports, 2022 Phosphatidylserine (PS) is a critical lipid factor in the assembly and spread of numerous lipid-enveloped viruses. Here, we describe the ability of the Ebola virus (EBOV) matrix protein eVP40 to induce clustering of PS and promote viral budding in vitro, as well as the ability of an FDA-approved drug, fendiline, to reduce PS clustering and subsequent ...
Monica L Husby +9 more
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