Results 61 to 70 of about 664,008 (371)

The Ebola Virus Matrix Protein Penetrates into the Plasma Membrane [PDF]

open access: yesJournal of Biological Chemistry, 2013
Ebola, a fatal virus in humans and non-human primates, has no Food and Drug Administration-approved vaccines or therapeutics. The virus from the Filoviridae family causes hemorrhagic fever, which rapidly progresses and in some cases has a fatality rate near 90%.
Enrico Gratton   +7 more
openaire   +5 more sources

Elucidating the Interacting Domains of Chandipura Virus Nucleocapsid Protein

open access: yesAdvances in Virology, 2013
The nucleocapsid (N) protein of Chandipura virus (CHPV) plays a crucial role in viral life cycle, besides being an important structural component of the virion through proper organization of its interactions with other viral proteins.
Kapila Kumar   +8 more
doaj   +1 more source

Molecular Mechanism of Arenavirus Assembly and Budding

open access: yesViruses, 2012
Arenaviruses have a bisegmented negative-strand RNA genome, which encodes four viral proteins: GP and NP by the S segment and L and Z by the L segment. These four viral proteins possess multiple functions in infection, replication and release of progeny ...
Shuzo Urata, Jiro Yasuda
doaj   +1 more source

The Viral Polymerase Complex Mediates the Interaction of Viral Ribonucleoprotein Complexes with Recycling Endosomes during Sendai Virus Assembly

open access: yesmBio, 2020
Paramyxoviruses are negative-sense single-stranded RNA viruses that comprise many important human and animal pathogens, including human parainfluenza viruses.
Emmanuelle Genoyer   +10 more
doaj   +1 more source

Structural Modeling of Human Immunodeficiency Virus Proteins

open access: yesBiomedical Engineering and Computational Biology, 2023
Human immunodeficiency virus (HIV) is an infectious virus that depletes the CD4 + T lymphocytes of the immune system and causes a chronic life-treating disease—acquired immunodeficiency syndrome (AIDS).
Amir Elalouf
doaj   +1 more source

Enhancement of Recombinant Protein Production in Transgenic Nicotiana benthamiana Plant Cell Suspension Cultures with Co-Cultivation of Agrobacterium Containing Silencing Suppressors. [PDF]

open access: yes, 2018
We have previously demonstrated that the inducible plant viral vector (CMViva) in transgenic plant cell cultures can significantly improve the productivity of extracellular functional recombinant human alpha-1-antiryspin (rAAT) compared with either a ...
Dandekar, Abhaya M   +3 more
core   +3 more sources

Nipah Virus-Like Particle Egress Is Modulated by Cytoskeletal and Vesicular Trafficking Pathways: a Validated Particle Proteomics Analysis

open access: yesmSystems, 2019
Classified as a biosafety level 4 (BSL4) select agent, Nipah virus (NiV) is a deadly henipavirus in the Paramyxoviridae family, with a nearly 75% mortality rate in humans, underscoring its global and animal health importance.
Gunner P. Johnston   +13 more
doaj   +1 more source

Beyond self-eating: The control of nonautophagic functions and signaling pathways by autophagy-related proteins. [PDF]

open access: yes, 2017
The identification of conserved autophagy-related proteins (ATGs) that mediate bulk degradation of cytosolic material laid the foundation for breakthroughs linking autophagy to a litany of physiological processes and disease conditions.
Cadwell, Ken, Debnath, Jayanta
core   +1 more source

Nucleocytoplasmic Shuttling of Influenza A Virus Proteins

open access: yesViruses, 2015
Influenza viruses transcribe and replicate their genomes in the nuclei of infected host cells. The viral ribonucleoprotein (vRNP) complex of influenza virus is the essential genetic unit of the virus.
Jing Li   +3 more
doaj   +1 more source

On the entropy of protein families [PDF]

open access: yes, 2015
Proteins are essential components of living systems, capable of performing a huge variety of tasks at the molecular level, such as recognition, signalling, copy, transport, ...
Barton, John   +4 more
core   +4 more sources

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