A novel kirkovirus may be associated with equine gastrointestinal disease
Abstract Background Many cases of equine enterocolitis are suspected to be infectious in nature, but no pathogen is identified in many cases. Objectives Perform next‐generation sequencing on faeces collected from cases of equine enterocolitis for the presence of novel viruses and determine if an identified novel virus is associated with cases of equine
Lillian M. B. Haywood +3 more
wiley +1 more source
Bacterial Extracellular Vesicles in the Pathogenesis and Treatment of Liver Diseases
Liver diseases are a major global health challenge, with current treatments inadequate. This review highlights the role of bacterial extracellular vesicles in liver inflammation, fibrosis, and metabolism. We also explore these from commensals and probiotics, their protective effects, and discuss research challenges and future therapeutic potential ...
Yakun Li +3 more
wiley +1 more source
Rapid viral metagenomics using SMART-9N amplification and nanopore sequencing
Ingra Morales Claro +21 more
openalex +1 more source
Differences in the Oral Microbiome Between Patients With and Without Oral Squamous Cell Carcinoma
ABSTRACT Background Although studies have demonstrated a relationship between pathogenic microorganisms and oral cancer, no study has demonstrated a relationship between changes in bacterial flora and oral squamous cell carcinoma (OSCC). Therefore, we investigated the association between oral microbiota and oral squamous cell carcinoma using ...
Satoshi Fukase +13 more
wiley +1 more source
The Computational Diet: A Review of Computational Methods Across Diet, Microbiome, and Health. [PDF]
Food and human health are inextricably linked. As such, revolutionary impacts on health have been derived from advances in the production and distribution of food relating to food safety and fortification with micronutrients. During the past two decades,
Eetemadi, Ameen +5 more
core
The Role of Viruses in the Pathogenesis of Periodontitis
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte +2 more
wiley +1 more source
The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis +2 more
wiley +1 more source
Multi‐Omics Signatures of Periodontitis and Periodontal Therapy on the Oral and Gut Microbiome
This multi‐omics study integrates shotgun metagenomics and NMR metabolomics to reveal coordinated microbial and metabolic signatures of periodontitis across the oral–gut axis. Non‐surgical periodontal therapy partially restored ecological and functional balance, supporting oral health as a modifiable driver of systemic microbial homeostasis.
Giacomo Baima +10 more
wiley +1 more source
Evaluation of bias induced by viral enrichment and random amplification protocols in metagenomic surveys of saliva DNA viruses [PDF]
Marcos Parras-Moltó +3 more
openalex +1 more source
A study of louse flies in the United Kingdom, Isle of Man, and Ireland found 212 different interactions between Hippoboscidae and their hosts, of which 70 were previously unrecorded. No louse flies were found on aquatic species of birds. Host‐switching to gulls (Laridae) has occurred during a period in which these species have started relying on ...
Denise C. Wawman +2 more
wiley +1 more source

