Results 121 to 130 of about 605,993 (221)

Exploring viral diversity in fermented vegetables through viral metagenomics

Food Microbiology
Fermented vegetables are traditionally produced using the endogenous microorganisms present in raw ingredients. While the diversity of bacteria and fungi in fermented vegetables has been relatively well studied, phage communities remain largely unexplored.
Cantuti Gendre, Julia, Le Marrec, Claire, Chaillou, Stéphane, Omhover-Fougy, Lysiane, Landaud, Sophie, Dugat-Bony, Eric   +5 more
openaire   +3 more sources

Geometric Intuition Enables Resource‐Efficient Screening for β‐Barrel‐Like Folds in Viral Structural Dark Matter

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Predicted protein structures now enable fold discovery beyond the reach of sequence homology, but scalable and interpretable methods remain limited. We present Cooper‐Beta, a resource‐efficient, chain‐resolved framework for detecting β‐barrel‐like folds from strand connectivity.
Shuyu Zhong, Yuying Jiang
wiley   +1 more source

Dataset S2 - Viral metagenomics in the clinical realm: lessons learned from a Swiss-wide ring trial

, 2019
<p>Dataset S2. FASTQ datasets for increment 2.</p> <p>Supplemental material of article "Viral metagenomics in the clinical realm: lessons learned from a Swiss-wide ring trial".</p ...
Lebrand, Aitana, Junier, Thomas, Junier, Thomas (8329332), Lebrand, Aitana (8424048)   +3 more
core   +1 more source

Comprehensive evaluation of metagenomic next‐generation sequencing for pathogen identification in patients with suspected infection: Establishment of a standardized validation workflow

VIEW, EarlyView.
Comprehensive evaluation of metagenomic next‐generation sequencing for pathogen identification in patients with suspected infection: Establishment of a standardized validation workflow. Abstract Metagenomic next‐generation sequencing (mNGS) enables unbiased identification of pathogens directly from clinical specimens. Despite its growing application in
Wen Shu, Qiaomei Guo, Han Yang, Huiqin Jiang, Chunyan He, Xueqing Wang, Yuting Fang, Yue Yin, Liwen Zhong, Zhijing Zhao, Jiatao Lou, Lin Wang   +11 more
wiley   +1 more source

Oral microbiome and homeostatic regulation of periodontal health: From dysbiosis to precision intervention

VIEW, EarlyView.
Periodontal homeostasis is maintained by coordinated interactions between the oral microbiome and host. Dysbiosis disrupts this ecological balance and contributes to periodontal disease, whereas multi‐omics, artificial intelligence, and microbiome‐based interventions provide emerging opportunities for precision diagnosis, ecological restoration, and ...
Xu Liu, Lei Meng, Wenzhu Song, Peiyu Wang, Bin Liu, Shihui Liu, Qi He, Bing Sun, Wanheng Li, Zhiwei Guan, Rui Dong, Qiang Feng   +11 more
wiley   +1 more source

Metagenomic insights into viral dynamics and function in Baijiu

Current Research in Food Science
Baijiu fermentation represents a sophisticated microbial-driven biochemical process mediated by complex microbial consortium. Despite extensive characterization of bacterial and fungal roles in fermentation systems, the virus remains a critical knowledge gap. In this study,we employed metagenomics to profile the dynamics of viral community in fermented
Huadong Zhang, Hongxia Zhang, Hai Du, Yan Zhang, Menghui Zhang, Xiaowei Yu, Yan Xu   +6 more
openaire   +2 more sources

Optimized recovery of viral DNA and RNA from blood plasma for viral metagenomics

Metagenomics is vastly improving our ability to discover new viruses, as well as their possible associations with disease. However, metagenomics has also changed our understanding of viruses in general.
Sanjuán, Rafael, Cebriá-Mendoza, María, Díaz-Villanueva, Wladimiro, Cuevas, José M.   +3 more
core   +1 more source

Single‐target contamination modeling in pathogen metagenomic sequencing via simple linear regression

VIEW, EarlyView.
Abstract A simple linear regression framework was developed to quantify contamination in pathogen metagenomic next‐generation sequencing (mNGS). The model was trained on simulated contamination samples generated by spiking HeLa cell backgrounds (1 × 105 cells/mL) with gradient concentrations of Streptococcus pneumoniae positive standards (5.6 × 106 ...
Xin Liu, Lin Wang, Jiatao Lou, Zhongyu Tan, Sihan Shen, Yanqi Wang, Chenxing Liao, Shengling Chen   +7 more
wiley   +1 more source

Herpesvirus and Adenotonsillar Hypertrophy in Chinese Children: An Epidemiological and Clinical Analysis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To investigate the possible association between adenotonsillar hypertrophy (ATH) and herpesviral infections in children, and to examine correlations between specific viral detection and clinical characteristics. Methods We enrolled 43 children aged 3–14 years with ATH (mean age 76.56 ± 25.65 months; 31 boys).
Ting‐Ting Ji, Miao Fan, Dan Yu, Xin Ni, Xiao‐Dan Li, Xin‐Yu Wang, Lu Lu, Wen Su, Li‐Xing Tang, Wei Zhang, Xiao Xiao, Yang Han, Lin Mei, Sheng‐Cai Wang   +13 more
wiley   +1 more source

Characterization of the Middle Ear Microbiome in Meniere's Disease by 16S rRNA Gene Sequencing Compared to Chronic Suppurative Otitis Media

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To investigate the middle ear microbiome in Meniere's disease (MD) patients. Methods Middle ear smears from 10 MD patients (ME group) and 10 chronic suppurative otitis patients (OE group) were collected during surgery and processed via 16S rRNA gene sequencing.
Yu‐Ting Tao, Lin Wang, Hong‐wei Zheng, Li‐Sheng Yu   +3 more
wiley   +1 more source