Results 141 to 150 of about 605,993 (221)

Advances in Spatial Heterogeneity and Cellular Localization Specificity of Intratumoral Bacteria

Cancer Science, EarlyView.
Spatial localization of intratumoral bacteria governs their functional roles in tumor progression, metastasis, and treatment responses, with guiding significance for clinical management, as reviewed across three spatial paradigms. ABSTRACT Bacteria in tumors are increasingly recognized to be a part of the tumor microenvironment and their biological ...
Minlan Ren, Jing Jia, Tingting Li, Yiwei Li, Nanxiang Shen, Yun Shi, Zhe Wang, Hao Fan, Guangli Sun, Guanying Xiong, Gang Li, Rui Peng   +11 more
wiley   +1 more source

Bringing Gene Therapy Into Real World Clinical Practice

Haemophilia, EarlyView.
ABSTRACT Introduction Adeno‐associated virus (AAV)‐based gene therapy for haemophilia has shifted therapeutic paradigms by enabling hepatic gene transfer, restoring endogenous clotting factor expression, and reducing reliance on conventional prophylactic treatments. Two products, valoctocogene roxaparvovec (haemophilia A) and etranacogene dezaparvovec (
Wolfgang Miesbach, Pratima Chowdary, Margareth C. Ozelo   +2 more
wiley   +1 more source

Lung microbiota of raccoon dogs (Nyctereutes procyonoides) using high-throughput sequencing

Frontiers in Microbiology
Pneumonia frequently causes mass mortality in raccoon dogs, resulting in significant economic loss. Additionally, raccoon dogs carry various zoonotic pathogens.
Wei Li, Wei Li, Xin Li, Jingran Cheng, Jie Liu, Jinjun Liu, Yu Wang, Wanzhe Yuan, Erjun Ren   +8 more
doaj   +1 more source

Can Artificial Intelligence Be Utilised to Develop Point‐of‐Care Endodontic Microbiological Technologies?

International Endodontic Journal, EarlyView.
ABSTRACT Background Primary or persistent endodontic disease is caused by microbial biofilms that irritate the pulp and periapical tissues. Extensive microbiological analyses of these biofilms and their constituent pathogens have revealed their diversity and complexity.
Ashraf F. Fouad
wiley   +1 more source

Adaptation to extreme environments: A review of Antarctic fish physiology

Journal of Fish Biology, EarlyView.
Abstract Having evolved in the chronically cold and thermally stable waters of the Southern Ocean (SO) for millions of years, Antarctic fish possess a suite of physiological specializations that enable them to survive at temperatures near the freezing point of seawater. Adaptations include the evolution of antifreeze proteins, modifications of membrane
Seungyeon Lee, Sachithra Amarin Hettiarachchi, Il‐Chan Kim, Jae‐Seong Lee, Thomas Desvignes, Julia M. York, Laura Ghigliotti, Jilda Alicia Caccavo, Jin‐Hyoung Kim   +8 more
wiley   +1 more source

Effects of N‐Acetylcysteine on Oxidative Status and Intestinal Health in Piglets (Sus scrofa domesticus L.): A PRISMA‐Based Systematic Review

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Oxidative stress is a critical challenge in intensive swine production, particularly during weaning, compromising intestinal integrity and animal performance. N‐acetylcysteine (NAC) has emerged as a multifunctional nutritional strategy to mitigate these effects due to its role as a glutathione precursor and signaling modulator. This systematic
Jessica Lucilene Cantarini Buchini, Karoline Silva de Camargo, Lucas Rocha Valfré, Núbia Michelle Vieira da Silva, Rodrigo Garófallo Garcia, Vivian Aparecida Rios e Castilho Heiss, Claudia Marie Komiyama, Fabiana Ribeiro Caldara   +7 more
wiley   +1 more source

Bridging the gap between genomic, phenotypic, and modeling data in picophytoplankton–virus interactions

Journal of Phycology, EarlyView.
Abstract We present a comprehensive synthesis of recent developments in methodological approaches to combine experimental and genomic studies of picophytoplankton–virus interactions. This synthesis will not only enhance our understanding of these relationships but also stimulate new hypotheses for the interpretation of metagenomic data and enrich ...
Luisa Listmann, Carina Peters, Anais Labecot, Raphaël Rousseau, Christie Baux, Maria Elisabetta Santelia, Eric Manirakiza, Nigel Grimsley, Sheree Yau, Sébastien Gourbiere, C‐Elisa Schaum, Gwenael Piganeau   +11 more
wiley   +1 more source

Lithochloron, a new genus of green algae residing in coral skeleton (Cladophorales, Chlorophyta)

Journal of Phycology, EarlyView.
Abstract Coral skeletons host diverse microbial communities, including endolithic green algae that contribute to holobiont functioning. The siphonous green alga Ostreobium (Bryopsidales) is arguably the best‐known coral endolith, but recent environmental sequencing has indicated that other lineages of green algae may also inhabit the coral skeleton ...
Heroen Verbruggen, Juntong Hu, Yuqun Du, Richard Wetherbee, Francesco Ricci, Manuel Poretti   +5 more
wiley   +1 more source

Development of MetaXplor: a viral metagenomics database. P29 [PDF]

, 2018
Recent metagenomics‐based studies have identified hundreds of unknown viruses living in environmental and ornamental hosts. While genomic, transcriptomic and metagenomic next generation sequencing (NGS) datasets are exponentially increasing, a large part
Claverie, Sohini, Sempere, Guilhem, Filloux, Denis, Roumagnac, Philippe, Petel, Adrien, Lefeuvre, Pierre, Mahé, Frédéric   +6 more
core  

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source