Results 101 to 110 of about 18,538 (220)
When to consider an inborn error of immunity: clues for physicians
Internal Medicine Journal, EarlyView.Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley +1 more source
CAPTVRED: An automated pipeline for viral tracking and discovery from capture-based metagenomics samples. [PDF]
Summary: Target Enrichment Sequencing or Capture-based metagenomics has emerged as an approach of interest for viral metagenomics in complex samples. However, these datasets are usually analyzed with standard downstream Bioinformatics analyses. CAPTVRED (
Itarte, Marta +6 more
core +1 more source
Journal of Diabetes Investigation, EarlyView.Using Mendelian randomization, TWAS/eQTL analysis, machine learning, and single‐cell RNA sequencing, this study identified gut microbiota taxa causally linked to type 2 diabetes, candidate mediator genes, and diagnostic markers (BEND7, BLVRA, C1orf85, and LAMC1).
Yu‐yang Chen +6 more
wiley +1 more source
Viral metagenomics for swine health [PDF]
Master of ScienceDepartment of Diagnostic Medicine/PathobiologyRoman PogranichniyViral metagenomic sequencing describes an unbiased technique to identify viruses present in a sample.
Feehan, Brandi
core
Journal of Fish Biology, EarlyView.Abstract Methods using environmental nucleic acids have become highly effective for monitoring aquatic biodiversity, with an array of suitable use cases, including metrics for fisheries assessment. Traditional methods for assessing fish populations often rely on invasive techniques with limited spatial and temporal coverage.
Ana Ramón‐Laca +6 more
wiley +1 more source
Viral populations in Tongyeong Bay, Korea, revealed by metagenomics [PDF]
, 2015 Viruses are ubiquitously present in most environments, from the air to the deep sea. In particular, the oceans possess numerous viruses. In this study, we examined viral communities in Goseong Bay, Korea, using metagenomics.
황진익 +3 more
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Fish Poxviruses on the Rise: Prospects for Aquatic Health
Journal of Fish Diseases, EarlyView.ABSTRACT Fish poxviruses are increasingly recognised as emerging pathogens of fish and should be considered in cases of unexplained gill or skin pathology. Carp edema virus (CEV), the causative agent of koi sleepy disease in common carp and koi (Cyprinus carpio), represents the first known example.
Mikolaj Adamek +9 more
wiley +1 more source
Journal of Fish Diseases, EarlyView.ABSTRACT Large‐scale double‐digest RAD sequencing (ddRADseq) datasets generated for genotyping are increasingly available in aquaculture, yet their unmapped reads remain largely unexplored for pathogen surveillance. Here, we evaluated the utility and limitations of repurposing unmapped ddRADseq reads to examine pathogen‐associated and disease ...
Nguyen Thanh Vu +11 more
wiley +1 more source
Journal of Fish Diseases, EarlyView.ABSTRACT Disease outbreaks and the associated reliance on antibiotics pose major constraints to the sustainability of modern aquaculture. As regulatory pressures increase and consumer demand shifts toward residue‐free production, diverse biological interventions are gaining prominence as viable alternatives to chemotherapeutics.
Mustafa Öz +5 more
wiley +1 more source
Genomic Medicine Sweden: Advancing precision medicine at the national level
Journal of Internal Medicine, EarlyView.Abstract High‐throughput sequencing has transformed clinical diagnostics of rare diseases (RD), cancer and infectious diseases by enabling the identification of disease‐causing genetic alterations and facilitating individualised treatment and care.
Anders Edsjö +58 more
wiley +1 more source