Results 111 to 120 of about 18,538 (220)

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Development of MetaXplor: a viral metagenomics database. P29 [PDF]

, 2018
Recent metagenomics‐based studies have identified hundreds of unknown viruses living in environmental and ornamental hosts. While genomic, transcriptomic and metagenomic next generation sequencing (NGS) datasets are exponentially increasing, a large part
Claverie, Sohini, Sempere, Guilhem, Filloux, Denis, Roumagnac, Philippe, Petel, Adrien, Lefeuvre, Pierre, Mahé, Frédéric   +6 more
core  

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Oral Health, Periodontitis, and Respiratory Diseases: Biological Pathways

Journal of Periodontal Research, EarlyView.
This narrative review aims to provide a comprehensive update on the potential mechanisms by which poor oral health and periodontitis impact lung health, focusing on pneumonia, COPD, and asthma. ABSTRACT Poor oral hygiene and periodontitis influence lung diseases such as pneumonia, chronic obstructive pulmonary disease (COPD), COVID‐19, and asthma.
Raluca P. Vacaru, Andreea C. Didilescu, Frank A. Scannapieco   +2 more
wiley   +1 more source

Periodontitis and Adverse Pregnancy Outcomes: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This narrative review aims to describe mechanisms linking periodontal diseases in pregnancy with adverse pregnancy outcomes. ABSTRACT Periodontal diseases, including both gingivitis and periodontitis, occur commonly among pregnant individuals. Both gingivitis and periodontitis are associated with adverse pregnancy outcomes (APOs) such as early ...
Gregory C. Valentine, Yiorgos A. Bobetsis, Benjamin C. Shayo, Peter Milgrom, Phoebus N. Madianos   +4 more
wiley   +1 more source

Viruses, Periodontitis, and Systemic Diseases

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the viral involvement in periodontitis and its relevance for systemic diseases. The oral cavity acts as an active viral reservoir and dissemination platform, where virus–microbiome interactions may promote dysbiosis, periodontitis progression, and systemic inflammatory effects, while the ...
Kim Natalie Solte, Yvonne L. Hernandez‐Kapila, Henrik Dommisch   +2 more
wiley   +1 more source

A multiplex assay to detect mosquito species, bloodmeal host source and Plasmodium in malaria vectors using Nanopore amplicon sequencing

Medical and Veterinary Entomology, EarlyView.
Insectary‐reared mosquitoes were simultaneously assessed for species identification, bloodmeal source analysis and Plasmodium detection, using a single multiplexed sequencing run on the MinION sequencing platform. The method was applied to 150 insectary‐reared mosquitoes, representing nine species blood‐fed with five vertebrate hosts and 40 samples for
E. Abby Rogers, Dieunel Derilus, Christopher Sandi, Lisa Reimer, Audrey Lenhart, Lucy Mackenzie Impoinvil   +5 more
wiley   +1 more source

Come together: Data sharing to support one health responses to vector‐borne disease threats

Medical and Veterinary Entomology, EarlyView.
A One Health framework integrating diverse data across human, animal and environmental sectors is essential for effective surveillance and response is vital for responding to vector‐borne disease risks. Communities adopting global data standards, depositing data in shared repositories, and responsible data use can significantly improve VBD data ...
Francis Windram, Sarah Kelly, Stanislav Modrak, Isabelle Dietrich, Corrado Minetti, Karen L. Mansfield, Frederik Seelig, Adam M. Fisher, Maisie Vollans, Nina Billows, Fahad Ahmed, Marta Shocket, Susana Campino, Scott Tytheridge, Sara L. Gandy, Estela Gonzalez, Jolyon M. Medlock, Matthew Baylis, Grant L. Hughes, David A. Ewing, Bethan V. Purse, Georgia Kirby, Clare Strode, Arran J. Folly, David Starns, Heather Ferguson, Simon Smith‐Mullally, Helen Roberts, Christopher M. Jones, Hannah Rose Vineer, Marion England, Christopher Sanders, Samraat Pawar, William D. Pearse, Steven M. White, Robert T. Jones, Lauren J. Cator   +36 more
wiley   +1 more source

DiscoVir: an automated, web-based pipeline for viral metagenomics. [PDF]

Microbiol Resour Announc
Krausfeldt LE, Subramanian P, Doan D, McCauley K, Dolan M, Hurt DE.   +5 more
europepmc   +1 more source