Results 131 to 140 of about 822,808 (285)

Metagenomic next‐generation sequencing provides a rapid and accurate diagnosis of pathogens in patients undergoing immunosuppressive therapy

Clinical and Translational Discovery, Volume 5, Issue 6, December 2025.
Metagenomics next‐generation sequencing is superior to that of conventional methods for the diagnosis of infections in patients treated with immunosuppressants. Blood samples could be used for rapid diagnosis of suspected viral infection, and samples from infectious sites have significant advantages in detecting bacterial and viral co‐infection ...
Lei Yue, Mengjiao Yuan, Chang Li, Miaomiao Zhang, Mengjia Qian, Qi Shen, Lingyan Wang, Yanxia Zhan, Bijun Zhu, Yujie Zhou, Hao Chen, Guoming Shi, Yunfeng Cheng   +12 more
wiley   +1 more source

The immunoproteasome‐specific inhibitor ONX 0914 reverses susceptibility to acute viral myocarditis

EMBO Molecular Medicine, 2018
Severe heart pathology upon virus infection is closely associated with the immunological equipment of the host. Since there is no specific treatment available, current research focuses on identifying new drug targets to positively modulate predisposing ...
N. Althof, Carl Christoph Goetzke, Meike Kespohl, K. Voss, A. Heuser, S. Pinkert, Z. Kaya, K. Klingel, A. Beling   +8 more
semanticscholar   +1 more source

Sex as a modifier of genetic risk for type 1 diabetes

Diabetes, Obesity and Metabolism, Volume 27, Issue 12, Page 6857-6868, December 2025.
Abstract Sex differences influence the pathogenesis of type 1 diabetes (T1D), yet most genetic studies have treated sex as a control covariate rather than a dynamic effect modifier. Sex influences immune cell behaviour, including CD4+ and CD8+ T cell activation, regulatory T cell stability, B cell autoantibody production, dendritic cell priming and ...
Hui‐Qi Qu, Hakon Hakonarson
wiley   +1 more source

May Fever Trigger Ventricular Fibrillation? [PDF]

, 2005
The clinical precipitants of ventricular fibrillation (VF) remain poorly understood. Clinical factors such as hypoxemia, acidosis or electrolyte imbalance, drug-related toxicity, autonomic nervous system disorders as well as viral myocarditis have been ...
Pasquié, Jean Luc
core   +1 more source

Time-course analysis of cardiac and serum galectin-3 in viral myocarditis after an encephalomyocarditis virus inoculation

PLoS ONE, 2019
Galectin-3 is a β-galactoside-binding lectin which is important in cell proliferation and apoptotic regulation. Recently, serum galectin-3 has been shown to have prognostic value as a biomarker in heart failure.
Kei Noguchi, H. Tomita, Tomohiro Kanayama, Ayumi Niwa, Y. Hatano, Masato Hoshi, S. Sugie, Hideshi Okada, M. Niwa, A. Hara   +9 more
semanticscholar   +1 more source

Infection risk in atopic dermatitis patients treated with biologics and JAK inhibitors: BioDay results

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 12, Page 2056-2068, December 2025.
This cohort study of 1793 atopic dermatitis patients (aged ≥ 12) found higher infection rates with Janus kinase inhibitor treatment compared to biologic treatment, particularly for herpes infections, with a history of viral or fungal skin infection as a risk factor associated with infection.
Lian F. van der Gang, Keneshka Atash, Nicolaas P. A. Zuithoff, Inge Haeck, Celeste M. Boesjes, Octavian I. Bacoş‐Cosma, Laura Loman, Marijke Kamsteeg, Simone Stadhouders‐Keet, Albert J. Oosting, Anneke M. T. van Lynden‐van Nes, Klaziena Politiek, Antoni Gostynksi, Lisette Berntsen‐Zandbergen, Wianda A. Christoffers, Annebeth Flinterman, Wouter R. H. Touwslager, Berit Velstra, Shiarra M. Stewart, Francine C. van Erp, Marlies de Graaf, Marie‐Louise A. Schuttelaar, Marjolein S. de Bruin‐Weller   +22 more
wiley   +1 more source

Coxsackievirus B3 Infection Induced Viral Myocarditis by Regulating the Expression Pattern of Chemokines in Cardiac Myocytes

Iranian Journal of Allergy, Asthma and Immunology, 2009
Viral myocarditis is a common cardiovascular disease, which has greatly threatened human health. However, up to now, the pathogenesis of viral myocarditis has been unclear, which leads to the lack of its effective treatments.
Shen Yan, Cheng Kan Quan, Wei Chu Yi, Dong Xiong Si   +3 more
doaj  

Fulminant viral myocarditis after rituximab therapy in pediatric nephrotic syndrome [PDF]

, 2013
Anne‐Laure Sellier‐Leclerc, Emré Belli, Valérie Guérin, Peter Dorfmüller, Georges Deschênes   +4 more
openalex   +1 more source

The cholinergic anti-inflammatory pathway ameliorates acute viral myocarditis in mice by regulating CD4+ T cell differentiation

Virulence, 2018
Many studies have found that abnormalities in the proportion and differentiation of CD4+ T cells (Th cells) are closely related to the pathogenesis of viral myocarditis (VMC). Our previous research indicates that the cholinergic anti-inflammatory pathway
De-Pu Zhou, Li-sha Ge, Guangwu Chen, Xiaohong Gu, Xing Chao, Zheng Cheng, Wenwen Zhang, Li Jia, Jiajin Lin, M. Chu, Yue-chun Li   +10 more
semanticscholar   +1 more source

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

Veterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis, Gad Baneth, Silvia Colombo, Filipe Dantas‐Torres, Lluís Ferrer, Alessandra Fondati, Guadalupe Miró, Laura Ordeix, Domenico Otranto, Chiara Noli   +9 more
wiley   +1 more source