Results 141 to 150 of about 822,808 (285)

Unmasking Idiopathic Inflammatory Myopathy: A Case of Proximal Weakness in a Young Male With Co‐Occurring Vitamin D Deficiency

open access: yesClinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Idiopathic inflammatory myopathy (IIM) encompasses rare autoimmune disorders causing muscle inflammation and weakness, with subtypes including dermatomyositis, necrotizing myopathy, antisynthetase syndrome, and inclusion body myositis. This case report details a 25‐year‐old South Asian male presenting with a 60‐day history of progressive ...
Ibrahim Khalil   +3 more
wiley   +1 more source

THE EVOLUTION OF UNDERSTANDING OF THE IMMUNE SYSTEM'S ROLE IN THE PATHOGENESIS OF INFLAMMATORY MYOCARDIAL DISEASES: TH17-MEDIATED IMMUNE MECHANISMS

open access: yesКубанский научный медицинский вестник, 2014
The review article discusses recent advances in our understanding of viral myocarditis such as pathogenic role of infection and immune mechanisms in acute, sub-acute and chronic phases of the disease.
N. R. Paleev   +8 more
doaj  

Clinical application of single‐cell RNA sequencing in disease and therapy

open access: yesClinical and Translational Medicine, Volume 15, Issue 11, November 2025.
This review provides a comprehensive overview of the application of scRNA‐seq in revisiting the somatic cell evolutions in human diseases, as well as in biomarker discovery and drug development. Abstract Background The emergence of single‐cell RNA sequencing (scRNA‐seq) technology has revolutionized our capacity to study cell functions in complex ...
Aisha Shigna Nadukkandy   +3 more
wiley   +1 more source

Silencing MicroRNA-155 Attenuates Cardiac Injury and Dysfunction in Viral Myocarditis via Promotion of M2 Phenotype Polarization of Macrophages

open access: yesScientific Reports, 2016
Macrophage infiltration is a hallmark feature of viral myocarditis. As studies have shown that microRNA-155 regulates the differentiation of macrophages, we aimed to investigate the role of microRNA-155 in VM.
Yingying Zhang   +8 more
semanticscholar   +1 more source

Determinants of Hospital Length of Stay in Herpes Zoster Patients: A Four‐Year Retrospective Study

open access: yesHealth Science Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background and Aims The Varicella‐zoster virus (VZV) primarily causes chickenpox and can later reactivate as herpes zoster (HZ) from latent VZV in sensory ganglia. HZ generally presents with unilateral dermatomal pain and vesicular skin eruptions.
Maryam Sadat Sadati   +5 more
wiley   +1 more source

Case Report: Three cases of clinically suspected viral myocarditis with recovery of left ventricular dysfunction

open access: yesFrontiers in Cardiovascular Medicine
Viral myocarditis is an important cause of non-ischemic cardiomyopathy. Multiple clinical manifestations have been reported, including acute heart failure, cardiogenic shock, and ventricular arrhythmias.
Jonathan Brown   +7 more
doaj   +1 more source

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

open access: yesMedicinal Research Reviews, Volume 45, Issue 6, Page 1850-1882, November 2025.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro   +5 more
wiley   +1 more source

Effect of Extra Virgin Olive Oil High in Bioactive Compounds on Atherosclerosis in Apoe‐Deficient Mice

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 22, November 2025.
EVOO with high content of squalene and the dialdehyde form of decarboxymethyl oleuropein aglycone in HBC consumed by mice reduced atherosclerotic foci and growth of plaques in both sexes. These findings were accompanied by decreases in APOA1, paraoxonase 1, lipoprotein oxidation, expression of CD36 in monocytes, increased differentiation of macrophages
Roberto Martínez‐Beamonte   +13 more
wiley   +1 more source

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