Journal of International Medical Research, 2020 Objectives To investigate the effect of lupeol in a mouse model of viral myocarditis induced by coxsackie virus B3 (CVB3). Methods Mice were separated into controls (DMEM, n = 20) and CVB3 infected groups (i.e., untreated CVB3 [n = 40]; CVB3 + lupeol 50 ...
Ming Xu +5 more
semanticscholar +1 more source
Sudden unexpected death related to enterovirus myocarditis: histopathology, immunohistochemistry and molecular pathology diagnosis at post-mortem [PDF]
, 2012 BACKGROUND: Viral myocarditis is a major cause of sudden unexpected death in children and young adults. Until recently, coxsackievirus B3 (CVB3) has been the most commonly implicated virus in myocarditis.
Imed Gaaloul +7 more
core +1 more source
Impact of Rapid Exome Sequencing on Pediatric Patients With Cardiomyopathy and Acute Heart Failure
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Few studies describe the impact of rapid exome sequencing (ES) on pediatric cardiomyopathy in urgent clinical settings. Here, we retrospectively report the impact of rapid singleton ES in pediatric patients presented with acute heart failure and isolated cardiomyopathy or myocarditis, between 2021 and 2023 at a single tertiary care center.
Tameemi Abdalla Moady +10 more
wiley +1 more source
A misleading CMV myocarditis during the COVID-19 pandemic: case report
The Pan African Medical Journal, 2020 Coronavirus disease 2019 (COVID-19) has been reported as the possible cause of acute myocarditis. Myocarditis is an inflammatory heart disease mostly caused by viral infections. Cytomegalovirus (CMV) primary infection is often not suspected as a cause of
Sara Oualim +4 more
doaj +1 more source
SARS-CoV-2-Induced Myocarditis: A State-of-the-Art Review
Viruses, 2023 In this review, we investigated whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can directly cause myocarditis with severe myocardial damage induced by viral particles.
Francesco Nappi +1 more
doaj +1 more source
Die Bedeutung des Low Molecular Weight Protein 7 (LMP7)- spezifischen Inhibitors ONX 0914 bei der viralen Infektion der Maus [PDF]
, 2018 Herzinsuffizienz ist eine der häufigsten Todesursachen. Ein Auslöser hierfür kann eine entzündliche Herzerkrankung sein, die durch virale Infektionen beispielsweise mit CoxsackievirusB3 ausgelöst werden können.
Goetzke, Carl Christoph
core +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli +17 more
wiley +1 more source
ESC Heart Failure, 2020 Left ventricular (LV) dysfunction in viral myocarditis is attributed to myocardial inflammation and fibrosis, inducing acute and long‐time cardiac damage. Interventions are not established.
C. Tschöpe +12 more
semanticscholar +1 more source
Pathophysiological Mechanisms of Cardiac Dysfunction in Transgenic Mice with Viral Myocarditis [PDF]
, 2023 Matthias Rohrbeck +22 more
openalex +1 more source
Mesenchymal stromal cells inhibit NLRP3 inflammasome activation in a model of Coxsackievirus B3-induced inflammatory cardiomyopathy [PDF]
, 2018 Inflammation in myocarditis induces cardiac injury and triggers disease progression to heart failure. NLRP3 inflammasome activation is a newly identified amplifying step in the pathogenesis of myocarditis.
A Abbate +43 more
core +1 more source