Results 91 to 100 of about 995,700 (356)

Control of human adenovirus type 5 gene expression by cellular Daxx/ATRX chromatin-associated complexes [PDF]

, 2013
Death domain–associated protein (Daxx) cooperates with X-linked α-thalassaemia retardation syndrome protein (ATRX), a putative member of the sucrose non-fermentable 2 family of ATP-dependent chromatin-remodelling proteins, acting as the core ATPase ...
Andreas Mund, Badens, Baker, Berk, Berube, Blanchette, Carolin Bürck, Chatterjee, Cheng, Chinnadurai, Cuchet-Lourenco, Dallaire, Dellaire, Dobner, Drane, Everett, Flint, Frisch, Gibbons, Glass, Goldberg, Goldberg, Gostissa, Graham, Groitl, Gunther, Hancock, Harlow, Hassan, Hollenbach, Ishov, Ishov, Jin, Kahyo, Kindsmuller, Kindsmuller, Kindsmüller, Ko, Komatsu, Kosulin, Lewis, Lewis, Li, Lukashchuk, Lukashchuk, Mandy Glass, Marton, Matsumoto, Maul, McFarlane, Michaelson, Mitsudomi, Mund, Nevels, Nevins, Nevins, Niforou, Okuwaki, Orazio, Parks, Pelka, Peter Groitl, Peter Wimmer, Placek, Querido, Roger D. Everett, Ross, Rubenwolf, Sabrina Schreiner, Salomoni, Sarah Kinkley, Sarnow, Schreiner, Schreiner, Schreiner, Shenk, Si, Song, Stracker, Takahashi, Tang, Thomas Dobner, Torii, Täuber, Täuber, Ullman, White, Williams, Wilson, Wong, Wong, Xu, Xue   +92 more
core   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

Viral Aspects of Protein Phosphorylation

Journal of General Virology, 1988
The discovery that the protein encoded by the transforming gene of Rous sarcoma virus (RSV) has protein kinase activity (Collett & Erikson, 1978) brought the subject of protein phosphorylation to the general attention of virologists. Retrovirus protein kinases have been extensively reviewed (e.g.
David P. Leader, Matilda Katan
openaire   +3 more sources

Nucleotide sequence and genomic organization of an ophiovirus associated with lettuce big-vein disease [PDF]

, 2002
The complete nucleotide sequence of an ophiovirus associated with lettuce big-vein disease has been elucidated. The genome consisted of four RNA molecules of approximately 7ò8, 1ò7, 1ò5 and 1ò4 kb.
Dullemans, A.M., Heuvel, J.F.J.M., van den, Verbeek, M., Wilk, F., van der   +3 more
core   +2 more sources

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

Discerning the relationship between geminiviral infection and vesicle trafficking using virus induced gene silencing [PDF]

, 2017
Tomato yellow leaf curl disease is one of the most important threats to tomato crops worldwide. One of its causal agents, Tomato yellow leaf curl Sardinian virus (TYLCSV) is a monopartite member of the genus Begomovirus from the family Geminiviridae. Due
Cana-Quijada, Pepe, Lozano-Durán, Rosa, R. Bejarano, Eduardo, Rosas-Díaz, Tábata   +3 more
core  

Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design

FEBS Letters, EarlyView.
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos, Doriana Ricciuti, Giada Mondanelli, Marco Gargaro   +3 more
wiley   +1 more source

A Calcium-Fortified Viral Matrix Protein [PDF]

Structure, 2014
In this issue of Structure, Leyrat and colleagues provide the first structural analysis of the human metapneumovirus (HMPV) matrix protein, a key regulator of viral assembly. Though structurally similar to other matrix proteins, two calcium binding sites suggest intriguing differences in regulation.
Rebecca Ellis Dutch, Gaya K. Amarasinghe
openaire   +3 more sources

Papilomavirus y cáncer de cérvix Papillomavirus in cervical carcinoma

Revista Colombiana de Obstetricia y Ginecología, 2003
La infección por el papilomavirus humano (pvh), es la enfermedad de transmisión sexual más común en el mundo. El pvh es causa necesaria para el desarrollo de cáncer de cérvix, pero no es suficiente ya que otros factores están involucrados en la ...
Hernán Cortés Yepes
doaj  

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

FEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli, Alex Fissore, Edoardo Salladini, Eleonora Raccuia, Simonetta Oliaro‐Bosso, Alessia Ruggiero, Rita Berisio, Milagros Medina, Adrian Velazquez‐Campoy, Salvatore Adinolfi, Mauro Marengo   +10 more
wiley   +1 more source