Results 141 to 150 of about 7,035,314 (359)
FEBS Open Bio, EarlyView.Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar +3 more
wiley +1 more source
Viral Infections in Type 2 Diabetes: A Dangerous Liaison
VirusesType 2 diabetes mellitus (T2DM) is increasing in incidence in many parts of the world and is becoming an important global health threat. T2DM results from a disturbance in glucose metabolism and is triggered by a combination of genetic and environmental ...
Azizul Haque, Anudeep B. Pant
doaj +1 more source
Binding of viral nuclear localization signal peptides to importin-α nuclear transport protein [PDF]
, 2023 Bryan M. Delfing +7 more
openalex +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Molecular mechanism of autophagy in porcine reproductive and respiratory syndrome virus infection
Frontiers in Cellular and Infection MicrobiologyPorcine reproductive and respiratory syndrome virus (PRRSV), a significant pathogen affecting the swine industry globally, has been shown to manipulate host cell processes, including autophagy, to facilitate its replication and survival within the host ...
Xiaoyong Chen, Ziding Yu, Wenfeng Li
doaj +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
FEBS Open Bio, EarlyView.Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Viral protein expression in producer and nonproducer clones of friend erythroleukemia cell lines [PDF]
, 1981 R. Anand, F Lilly, S K Ruscetti
openalex +1 more source
Drug and Anti-Viral Peptide Design to Inhibit the Monkeypox Virus by Restricting A36R Protein
, 2022 Mohammad Mohasin Miah +3 more
openalex +1 more source