Results 181 to 190 of about 928,330 (381)

Identification of Human Proteins vulnerable to multiple Organisms and their disease associations [PDF]

open access: yesarXiv, 2016
While most studies emphasize on certain aspects of Pathogen-Host Interactions (PHI), such as the preferential attachment of bacteria or virus to its human receptor homolog, studies have attempted to methodically classify interactions among pathogenic proteins and their host proteins.
arxiv  

Equi‐MOI ratio for rapid baculovirus‐mediated multiprotein co‐expression in insect cells integrating selenomethionine for structural studies

open access: yesFEBS Open Bio, EarlyView.
This study presents a versatile protocol for producing selenomethionine‐labeled multiprotein complexes, addressing challenges in structural biology such as experimental phasing in X‐ray crystallography. Its efficiency and adaptability make it valuable for researchers studying de novo, dynamic, or complex protein structures, promoting advancements in ...
Andrej Bitala   +3 more
wiley   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

Why large icosahedral viruses need scaffolding proteins: The interplay of Gaussian curvature and disclination interactions [PDF]

open access: yesarXiv, 2018
While small single stranded viral shells encapsidate their genome spontaneously, many large viruses, such as the Herpes virus or Infectious Bursal Disease Virus (IBDV), typically require a template, consisting of either scaffolding proteins or inner core.
arxiv  

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

open access: yesAging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal   +8 more
wiley   +1 more source

Evolutionary‐Distinct Viral Proteins Subvert Rice Broad‐Spectrum Antiviral Immunity Mediated by the RAV15‐MYC2 Module

open access: yesAdvanced Science
A variety of plant viruses employ different virulence strategies to achieve successful infection, resulting in abnormal plant development. However, the common pathogenicity of distinct viruses has rarely been studied.
Hehong Zhang   +10 more
doaj   +1 more source

Review of the application of dual‐energy CT combined with radiomics in the diagnosis and analysis of lung cancer

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Lung cancer is one of the most common malignant tumors in the world. Early detection and precise treatment are of great significance to clinical decision‐making and patient prognosis. As an emerging imaging technology, dual‐energy computed tomography (DECT) has increasingly prominent advantages in multi‐parameter and quantitative analysis in ...
Rongyu Zhang   +3 more
wiley   +1 more source

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