Results 201 to 210 of about 995,700 (356)

Requirement for c-ras proteins during viral oncogene transformation [PDF]

, 1986
Mark R. Smith, Steven J. DeGudicibus, Dennis W. Stacey   +2 more
openalex   +1 more source

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source

Midnolin inhibits coronavirus proliferation by degrading viral proteins. [PDF]

J Virol
Wang Y, Tong W, Qin W, Yang X, Yu H, Zheng H, Zhang W, Tong G, Wang C, Kong N, Shan T.   +10 more
europepmc   +1 more source

The avian retroviral integration protein cleaves the terminal sequences of linear viral DNA at the in vivo sites of integration [PDF]

, 1989
Michael Katzman, Richard A. Katz, A M Skalka, Jonathan Leis   +3 more
openalex   +1 more source

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

Advanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Sequences and Structures of Viral Proteins Linked to the Genomes (VPg) of RNA Viruses. [PDF]

Viruses
Schein CH.
europepmc   +1 more source

Anti-influenza virus cytotoxic T lymphocytes recognize the three viral polymerases and a nonstructural protein: responsiveness to individual viral antigens is major histocompatibility complex controlled [PDF]

, 1987
Jack R. Bennink, Jonathan W. Yewdell, Geoffrey L. Smith, Bernard Moss   +3 more
openalex   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

SARS-CoV-2 viral proteins trigger pain via TLR2/4-MyD88 pathway. [PDF]

Front Mol Neurosci
Su W, Wang X, Gu M, Zheng Q, Yu J, Mu D.
europepmc   +1 more source

Application of Denatured, Electrophoretically Separated, and Immobilized Lysates of Herpes Simplex Virus-Infected Cells for Detection of Monoclonal Antibodies and for Studies of the Properties of Viral Proteins [PDF]

, 1983
Daniel Braun, Lenore Pereira, Bodil Norrild, Bernard Roizman   +3 more
openalex   +1 more source