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Spatially Controlled 3‐D Multiplexed Aptamer Patterning in Hydrogels
A hydrogel platform based on norbornene‐functionalized polyvinyl alcohol enables high‐resolution, 3‐D multiplexed patterning of DNA aptamers via two‐photon polymerization. Two distinct aptamers are covalently immobilized with single micron‐scale precision across the x, y, and z dimensions.
Kevin Roost+9 more
wiley +1 more source
Extracellular vesicles derived from antigen-presenting cells pulsed with foot and mouth virus vaccine-antigens act as carriers of viral proteins and stimulate B cell response. [PDF]
Menay F+7 more
europepmc +1 more source
Two viral proteins translated from one open reading frame target different layers of plant defense. [PDF]
Mei Y+5 more
europepmc +1 more source
Viral proteins activate PARIS-mediated tRNA degradation and viral tRNAs rescue infection
Burman N+25 more
europepmc +1 more source
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VIRAL TRANSACTIVATING PROTEINS
Annual Review of Genetics, 1997▪ Abstract Many viruses utilize the cellular transcription apparatus to express their genomes, and they encode transcriptional regulatory proteins that modulate the process. Here we review the current understanding of three viral regulatory proteins.
Thomas Shenk, Jane Flint
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Relationship between viral RNA and viral protein synthesis
Virology, 1962Abstract Low concentrations of p-fluorophenylalanine (5–10 μg/ml) inhibit the maturation of Western equine encephalomyelitis and poliomyelitis viruses. Much higher concentrations are required (125 μg/ml) to inhibit the synthesis of the respective infectious RNA. By means of fluorescent antibodies against poliovirus, it was found that the formation of
Otmar Goetz+3 more
openaire +3 more sources
Viral complement regulatory proteins
Immunopharmacology, 1999The inactivation of complement provides cells and tissues critical protection from complement-mediated attack and decreases the associated recruitment of other inflammatory mediators. In an attempt to evade the host immune response, viruses have evolved two mechanisms to acquire complement regulatory proteins.
Joseph M. Ahearn, Ariella M. Rosengard
openaire +3 more sources
Modulation of mitochondria by viral proteins
Life Sciences, 2023Mitochondria are dynamic cellular organelles with diverse functions including energy production, calcium homeostasis, apoptosis, host innate immune signaling, and disease progression. Several viral proteins specifically target mitochondria to subvert host defense as mitochondria stand out as the most suitable target for the invading viruses.
Reshu, Saxena+5 more
openaire +2 more sources