Results 311 to 320 of about 7,035,314 (359)
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VIRAL TRANSACTIVATING PROTEINS
Annual Review of Genetics, 1997▪ Abstract Many viruses utilize the cellular transcription apparatus to express their genomes, and they encode transcriptional regulatory proteins that modulate the process. Here we review the current understanding of three viral regulatory proteins.
J, Flint, T, Shenk
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Structural disorder in viral proteins.
Chemical Reviews, 2014B. Xue +6 more
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Viral complement regulatory proteins
Immunopharmacology, 1999The inactivation of complement provides cells and tissues critical protection from complement-mediated attack and decreases the associated recruitment of other inflammatory mediators. In an attempt to evade the host immune response, viruses have evolved two mechanisms to acquire complement regulatory proteins.
A M, Rosengard, J M, Ahearn
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Viral chemokine-binding proteins
Journal of Leukocyte Biology, 2002AbstractThe chemokines are a large family of small signaling proteins that bind to G-protein-coupled receptors (GPCRs) on target cells and mediate the directional migration of immune cells into sites of infection or inflammation. The large DNA viruses, particularly the poxviruses and herpesviruses, have evolved several mechanisms to corrupt the normal ...
Bruce T, Seet, Grant, McFadden
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Relationship between viral RNA and viral protein synthesis
Virology, 1962Abstract Low concentrations of p-fluorophenylalanine (5–10 μg/ml) inhibit the maturation of Western equine encephalomyelitis and poliomyelitis viruses. Much higher concentrations are required (125 μg/ml) to inhibit the synthesis of the respective infectious RNA. By means of fluorescent antibodies against poliovirus, it was found that the formation of
E, WECKER, K, HUMMELER, O, GOETZ
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Viral protein kinases and protein phosphatases
Pharmacology & Therapeutics, 1993Certain large DNA viruses (e.g. herpesviruses and poxviruses) encode proteins related to cellular protein-serine/threonine kinases, and Hepatitis B virus and vesicular stomatitis virus may encode structurally different protein kinases. Other viruses activate cellular protein kinases, e.g. interferon-induced eukaryotic initiation factor-2 kinase, growth
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Virally Encoded Chemokine Binding Proteins
Mini-Reviews in Medicinal Chemistry, 2005Virus-encoded immune evasion mechanisms provide information on viral pathogenesis and offer a unique opportunity to identify new strategies of immune modulation. Secreted proteins that bind a broad range of chemokines have been identified in recent years in poxviruses and herpesviruses.
Louise M C, Webb, Antonio, Alcami
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1995
Since the discovery of the human immunodeficiency viruses types 1 (HIV-1) and 2 (HIV-2) as the causative agents of acquired immunodeficiency syndrome (AIDS) (Barre-Sinoussi et al. 1983; Clavel et al. 1987; Papovic et al. 1984) and the isolation of related lentiviruses from several species of Old World monkeys, much has been learned about their biology ...
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Since the discovery of the human immunodeficiency viruses types 1 (HIV-1) and 2 (HIV-2) as the causative agents of acquired immunodeficiency syndrome (AIDS) (Barre-Sinoussi et al. 1983; Clavel et al. 1987; Papovic et al. 1984) and the isolation of related lentiviruses from several species of Old World monkeys, much has been learned about their biology ...
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2016
Cancer immunotherapy is a rapidly evolving field and the search for appropriate targets to come up with robust immunotherapeutic strategies for the treatment of cancers is a continuous process. Viral-like proteins are known to have an important role in the oncogenesis and their potential as cancer therapeutic targets is yet to be completely explored ...
Lavakumar Karyampudi, Keith L. Knutson
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Cancer immunotherapy is a rapidly evolving field and the search for appropriate targets to come up with robust immunotherapeutic strategies for the treatment of cancers is a continuous process. Viral-like proteins are known to have an important role in the oncogenesis and their potential as cancer therapeutic targets is yet to be completely explored ...
Lavakumar Karyampudi, Keith L. Knutson
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Identification of Immunoreactive Viral Proteins
2003Several diagnostic tools are available for the identification of acute and latent viral infections. Although newly developed nucleic acid amplification methods, such as the polymerase chain reaction (PCR), have proved to be very useful diagnostic procedures, conventional methods, such as cell culture and serology, still play an important role in viral ...
W, Hinderer, B, Plachter, R, Vornhagen
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