Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System
Advanced Functional Materials, EarlyView.A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim +4 more
wiley +1 more source
Efficient HIV-1 in vitro reverse transcription: optimal capsid stability is required
Signal Transduction and Targeted Therapy, 2021 Ryan C. Burdick, Vinay K. Pathak
doaj +1 more source
The Majority of Freshly Sorted Simian Immunodeficiency Virus (SIV)-Specific CD8+T Cells Cannot Suppress Viral Replication in SIV-Infected Macrophages [PDF]
, 2012 Lara Vojnov +9 more
openalex +1 more source
Advanced Functional Materials, EarlyView.MAMAWEL is introduced as the first calibration‐free potentiometric sensor for at‐home mastitis diagnosis. By measuring the sodium‐to‐potassium ratio in breast milk, the device reliably differentiates between healthy and mastitis‐affected samples with less than 10% error.
Ali Soleimani +9 more
wiley +1 more source
G-quadruplex as an essential structural element in cytomegalovirus replication origin
Nature CommunicationsG-quadruplex (G4) structures are found in eukaryotic cell replication origins, but their role in origin function remains unclear. In this study G4 motifs are found in the lytic DNA replication origin (oriLyt) of human cytomegalovirus (HCMV) and ...
Daegyu Park +7 more
doaj +1 more source
Mimivirus transcription and translation occur at well-defined locations within amoeba host cells
Journal of VirologyMany giant viruses replicate in the cytoplasm in viral factories. How exactly these viral factories are established and where the different steps of the replication cycle occur remain largely obscure.
Lotte Mayer +4 more
doaj +1 more source
PLoS Pathogens, 2017 We have shown previously that Sp100 (a component of the ND10 nuclear body) represses transcription, replication and establishment of incoming human papillomavirus (HPV) DNA in the early stages of infection.
Wesley H Stepp +4 more
doaj +1 more source
Inactivating SARS‐CoV‐2 Virus with MOF‐Composites as Smart Face Masks
Advanced Functional Materials, EarlyView.In situ preparation and functionalization of MOF@Cotton fabrics as smart face masks for the immobilization of proteins and inactivation viruses, such as SARS‐CoV‐2. Abstract The significant impact of the SARS‐CoV‐2 (COVID‐19) pandemic outbreak on people's lives has highlighted the urgent need for effective personal protective equipment.
Romy Ettlinger +9 more
wiley +1 more source
ViralZone: recent updates to the virus knowledge resource [PDF]
, 2017 ViralZone (http://viralzone.expasy.org) is a knowledge repository that allows users to learn about viruses including their virion structure, replication cycle and host-virus interactions.
Bitter, Hans +8 more
core
The Potato Virus X TGBp2 Protein Plays Dual Functional Roles in Viral Replication and Movement [PDF]
, 2018 Xiaoyun Wu +6 more
openalex +1 more source