Results 171 to 180 of about 366,840 (272)

Publisher Correction: Herpesviruses mimic zygotic genome activation to promote viral replication. [PDF]

Nat Commun
Neugebauer E, Walter S, Tan J, Drayman N, Franke V, van Gent M, Pennisi S, Veratti P, Stein KS, Welker I, Tay S, Verjans GMGM, Timmers HTM, Akalin A, Landthaler M, Ensser A, Wyler E, Full F.   +17 more
europepmc   +1 more source

Navigating a Fine Balance: Point-Mutant Cheater Viruses Disrupt the Viral Replication Cycle. [PDF]

Mol Biol Evol
Meir M, Kahn A, Farage C, Maoz Y, Harel N, Ben Zvi A, Segev S, Volkov M, Yahud R, Gophna U, Stern A.   +10 more
europepmc   +2 more sources

Depletion of Hepatic SREBP2 Protects Against Hypercholesterolemia and Atherosclerosis through the ANGPTL3‐LPL Axis

Advanced Science, EarlyView.
This study reveals a novel crosstalk between hepatic SREBP2‐mediated cholesterol biosynthesis pathway and peripheral lipoprotein lipase‐mediated lipolysis pathway in the regulation of systemic lipid metabolism. Notably, the lipid‐lowering effects of SREBP2 inhibition are independent of a functional LDL receptor, highlighting the potential of acute ...
Yifan Wang, Jia You Sarafina Choe, Yu Shi, Thi Tun Thi, Xiaoyun Cao, Yang Hu, Kai Yan Cheng, Hui Li, Yang Ji, Yan Liu, Matthew Ackers‐Johnson, Roger S.Y. Foo, Yujia Shen, Haojie Yu   +13 more
wiley   +1 more source

ASFV infection induces lipid metabolic disturbances and promotes viral replication. [PDF]

Front Microbiol
Chu X, Ge S, Li Y, Zhang Q, Cui X, Zuo Y, Li R, Sun H, Yin L, Wang Z, Li J, Xiao Y, Wang Z.   +12 more
europepmc   +1 more source

Viral DNA and mRNA expression correlate with the stage of human immunodeficiency virus (HIV) type 1 infection in humans: evidence for viral replication in all stages of HIV disease [PDF]

, 1992
N L Michael, Maryanne Vahey, Donald S. Burke, Robert Redfield   +3 more
openalex   +1 more source

Targeting Senescence with Apigenin Improves Chemotherapeutic Efficacy and Ameliorates Age‐Related Conditions in Mice

Advanced Science, EarlyView.
As a plant‐derived flavonoid, apigenin directly targets PRDX6 to inhibit its PLA2 activity, blocking HSPA8 activation and disturbing its interactions with ATM and p38MAPK in senescent cells. By dampening wide spectrum expression of the SASP, apigenin prevents loss of tissue homeostasis, improves organ function, and alleviates multiple age‐related ...
Hongwei Zhang, Qixia Xu, Zhirui Jiang, Rong Sun, Qun Wang, Sanhong Liu, Xin Luan, Judith Campisi, James L. Kirkland, Weidong Zhang, Yu Sun   +10 more
wiley   +1 more source

Spring viraemia of carp virus modulates the time-dependent unfolded protein response to facilitate viral replication. [PDF]

Front Immunol
Romero A, Figueras A, Novoa B.
europepmc   +1 more source

Inhibition of replication and expression of human T-cell lymphotropic virus type III in cultured cells by exogenous synthetic oligonucleotides complementary to viral RNA.

, 1986
Paul C. Zamecnik, John Goodchild, Y‐h. Taguchi, Prem S. Sarin   +3 more
openalex   +1 more source

Analysis of the earliest steps of hepadnavirus replication: genome repair after infectious entry into hepatocytes does not depend on viral polymerase activity [PDF]

, 1993
Josef Köck, H J Schlicht
openalex   +1 more source

Dissecting the Spatial and Single‐Cell Transcriptomic Architecture of Cancer Stem Cell Niche Driving Tumor Progression in Gastric Cancer

Advanced Science, EarlyView.
A single‐cell and spatial transcriptional atlas reveals the architecture of human gastric cancer stem cell (CSC) niche and the developmental trajectory of CSCs. These CSCs interact with immunosuppressive immune cells thereby constructing immune‐suppressive niche, and inflammatory cancer‐associated fibroblast (iCAFs) to enhance stemness through ...
Guangyu Zhang, Xin Zhang, Wenting Pan, Xizhao Chen, Lingfei Wan, Chunjie Liu, Yuting Yong, Yue Zhao, Shuli Sang, Lihua Zhang, Sheng Yao, Yushu Guo, Mingmei Wang, Xinhui Wang, Guangdun Peng, Xinlong Yan, Yanchun Wang, Min Zhang   +17 more
wiley   +1 more source