Results 121 to 130 of about 361,433 (303)

Tomato marchitez virus, a new plant picorna-like virus from tomato related to tomato torrado virus

, 2008
A new virus was isolated from a tomato plant from the state of Sinaloa in Mexico. This plant showed symptoms locally known as `marchitez disease¿: severe leaf necrosis, beginning at the base of the leaflets, and necrotic rings on the fruits.
Verbeek, M., Dullemans, A.M., Heuvel, J.F.J.M., van den, Maris, P.C., Vlugt, R.A.A., van der   +4 more
core   +1 more source

Roles of African swine fever virus structural proteins in viral infection

Journal of Veterinary Research, 2017
African swine fever virus (ASFV) is a large, double-stranded DNA virus and the sole member of the Asfarviridae family. ASFV infects domestic pigs, wild boars, warthogs, and bush pigs, as well as soft ticks (Ornithodoros erraticus), which likely act as a ...
Jia Ning, Ou Yunwen, Pejsak Zygmunt, Zhang Yongguang, Zhang Jie   +4 more
doaj   +1 more source

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

Advanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino, Lucia Pappagallo, Francesca De Chirico, Luca Boselli, Hazem Ahmed, Luca Spagnoletti, Giovanni Pittaluga, Paolo Emidio Costantini, Matteo Calvaresi, Pier Paolo Pompa, Alberto Danielli, Fabio Benfenati, Valentina Castagnola   +12 more
wiley   +1 more source

Nucleotide bias of DCL and AGO in plant anti-virus gene silencing [PDF]

, 2010
Plant Dicer-like (DCL) and Argonaute (AGO) are the key enzymes involved in anti-virus post-transcriptional gene silencing (AV-PTGS). Here we show that AV-PTGS exhibited nucleotide preference by calculating a relative AV-PTGS efficiency on processing ...
Hui Wang, Tamas Dalmay, Kazusato Ohshima, Walsh, John A., Linfeng Huang, Ohshima, Kazusato, Wang, Hui, Denise W. Pallett, Pallett, Denise W., Liang Wang, Li, Zhigang, Thien Ho, Zhigang Li, John A. Walsh, Huang, Linfeng, Ho, Thien, Wang, Liang, Dalmay, Tamas   +17 more
core   +1 more source

Structural and Functional Insights into Viral and Fungal Proteins Involved in Chronic Inflammation and Their Biologic Treatments

Pharmaceutics
Chronic inflammation constitutes a significant characteristic of sustained infections caused by viral and fungal pathogens, with a strong correlation to the development of cancer, autoimmune disorders, and tissue fibrosis.
Mohamed Halawa, Alicia L. Gallo, Valerie J. Carabetta   +2 more
doaj   +1 more source

Self‐Assembled Skin Equivalents with Monoclonal CRISPR/Cas9‐Modified N/TERT‐1 Keratinocytes: A Cutting‐Edge model for Human Skin and its Diseases

Advanced Healthcare Materials, EarlyView.
Self‐assembled, scaffold‐free full‐thickness skin equivalents with monoclonal, genetically modified N/TERT‐1 keratinocytes represent a novel in vitro model of human skin and skin diseases. The model is highly robust, reproducible, physiologically relevant, and suitable for high‐throughput applications.
Marta Slaufova, Tugay Karakaya, Michela Di Filippo, Thomas Kündig, Hans‐Dietmar Beer   +4 more
wiley   +1 more source

Generation of cell lines to complement Adenovirus vectors using recombination-mediated cassette exchange [PDF]

, 2010
Background Adenovirus serotype 5 (Ad5) has many favourable characteristics for development as a gene therapy vector. However, the utility of current Ad5 vectors is limited by transient transgene expression, toxicity and immunogenicity.
Farley, Daniel C., Daniel C Farley, Farley Daniel C, Leppard, Keith, Susan J Morris, Morris, S. J. (Susan J.), Keith N Leppard, Leppard Keith N, Morris Susan J   +8 more
core   +1 more source

Unlocking the secrets of Feline calicivirus: advances in structural and nonstructural proteins and its role as a key model for other Caliciviruses

Virology Journal
Feline calicivirus (FCV) is a highly contagious pathogen responsible for respiratory infections, lingual ulceration, oral ulcers and systemic diseases in cats, posing a significant risk to feline family worldwide.
Sana Asif, Deng Yingkun, Chunchun Meng
doaj   +1 more source

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

Entrapment of viral capsids in nuclear PML cages is an intrinsic antiviral host defense against varicella-zoster virus. [PDF]

, 2011
The herpesviruses, like most other DNA viruses, replicate in the host cell nucleus. Subnuclear domains known as promyelocytic leukemia protein nuclear bodies (PML-NBs), or ND10 bodies, have been implicated in restricting early herpesviral gene expression.
Baiker Armin, Sommer, Marvin, Nour Adel M., Sen Nandini, Wang, Li, Leigh Zerboni, Nandini Sen, Reichelt, Mike, Adel M. Nour, Mike Reichelt, Zerboni, Leigh, Marvin Sommer, Perrino, John, Reichelt Mike, Arvin Ann M., Arvin, Ann M., Ann M Arvin, Nour, Adel M., Baiker, Armin, John Perrino, Zerboni Leigh, Ann M. Arvin, Sommer Marvin, Adel M Nour, Perrino John, Li Wang, Armin Baiker, Sen, Nandini, Wang Li   +28 more
core   +1 more source