Results 121 to 130 of about 1,560,419 (396)
Background: Lately, many viruses emerged or re-emerged from the obscurity and became considerable threats to the global health, raising alarms concerning their constant epidemic transmissions. A very important public health concern of those viruses is the continuous circulation amongst the population of the immunologically naive, susceptible hosts ...
openaire +2 more sources
SARS‐CoV‐2 Is Linked to Brain Volume Loss in Multiple Sclerosis
ABSTRACT Objective The impact of SARS‐CoV‐2 infection on brain and spinal cord pathology in patients with multiple sclerosis (pwMS) remains unclear. We aimed to describe changes in brain lesion activity and brain and spinal cord volumes following SARS‐CoV‐2 infection.
Tomas Uher+12 more
wiley +1 more source
Macaque models of human infectious disease. [PDF]
Macaques have served as models for more than 70 human infectious diseases of diverse etiologies, including a multitude of agents-bacteria, viruses, fungi, parasites, prions.
Abe+330 more
core +1 more source
Coagulapathies after vaccination against SARS-CoV-2 may be derived from a combination effect of SARS-CoV-2 spike protein and adenovirus vector-triggered signaling pathways [PDF]
The novel coronavirus SARS-CoV-2 has resulted in a global pandemic with worldwide 6-digital infection rates and thousands death tolls daily. Enormeous effords are undertaken to achieve high coverage of immunization in order to reach herd immunity to stop spreading of SARS-CoV-2 infection. Several SARS-CoV-2 vaccines, based either on mRNA, viral vectors,
arxiv
Evolutionary reversion of live viral vaccines: Can genetic engineering subdue it?
Attenuated, live viral vaccines have been extraordinarily successful in protecting against many diseases. The main drawbacks in their development and use have been reliance on an unpredictable method of attenuation and the potential for evolutionary ...
James J. Bull
semanticscholar +1 more source
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source
Development of an experimental inactivated PRRSV vaccine that induces virus-neutralizing antibodies [PDF]
Porcine reproductive and respiratory syndrome virus (PRRSV) can induce reproductive disorders and is involved in the porcine respiratory disease complex, causing tremendous economic losses to the swine industry.
Delputte, Peter+4 more
core +3 more sources
Viral Vaccines and Antiviral Therapy
In this article the authors review the important viral infections affecting humans, and how they are prevented by vaccines and controlled by antiviral drugs. The different types of drugs and vaccines are listed and their mechanisms of action are discussed.
Alex Tselis, John Booss
openaire +2 more sources
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley +1 more source
Hepatitis E Virus Infection in Voluntary Blood Donors in the Russian Federation
Transfusion-transmitted hepatitis E virus (HEV) infection is an increasing concern in many countries. We investigated the detection rate of HEV viremia in blood donors in Russia. A total of 20,405 regular repetitive voluntary non-renumerated blood donors
Ilya A. Potemkin+16 more
doaj +1 more source