Results 151 to 160 of about 370,832 (346)

Immunogenicity of Viral Vaccines in the Italian Military. [PDF]

Biomedicines, 2021
Ferlito C, Biselli R, Visco V, Cattaruzza MS, Capobianchi MR, Castilletti C, Lapa D, Nicoletti L, Marchi A, Magurano F, Ciccaglione AR, Chionne P, Madonna E, Donatelli I, Calzoletti L, Fabiani C, Biondo MI, Teloni R, Mariotti S, Salerno G, Picchianti-Diamanti A, Salemi S, Caporuscio S, Autore A, Lulli P, Borelli F, Lastilla M, Nisini R, D'Amelio R.   +28 more
europepmc   +1 more source

Four viral genes independently contribute to attenuation of live influenza A/Ann Arbor/6/60 (H2N2) cold-adapted reassortant virus vaccines [PDF]

, 1988
M H Snyder, Robert F. Betts, Dan C. DeBorde, E L Tierney, M L Clements, D A Herrington, S D Sears, Raphael Dolin, H. F. Maassab, Brian R. Murphy   +9 more
openalex   +1 more source

Payload‐Driven Design of Polymeric Carriers for Nucleic Acid Delivery: Insights from Structure–Function Relationships

Advanced Science, EarlyView.
Polymeric carriers provide versatile platforms for nucleic acid delivery. This review introduces a novel perspective inspired by protein structural organization to explore structure–function relationships of polymeric carriers, highlighting requirements of different nucleic acid payloads.
Hanieh Moradian, Charlotte Maeve Dunne, Manfred Gossen, Matthias Hartlieb   +3 more
wiley   +1 more source

A WHO global framework to guide investigations into origins of potentially epidemic and pandemic pathogens

Nature Communications
In outbreak situations involving a novel pathogen timely and coordinated response is crucial. The WHO Scientific Advisory Group for the Origins of Novel Pathogens recently released a global framework to guide future scientific investigations into the ...
The Scientific Advisory Committee for the Origins of Novel Pathogens (SAGO) and WHO SAGO Secretariat
doaj   +1 more source

Targeting Endothelial KDM5A to Attenuate Aging and Ameliorate Age‐Associated Metabolic Abnormalities

Advanced Science, EarlyView.
This study identifies endothelial KDM5A as a key regulator of aging. KDM5A deficiency accelerates aging by enhancing H3K4me3‐mediated FABP4 expression, disrupting fatty acid metabolism, and promoting multi‐organ senescence. KDM5A restoration or FABP4 inhibition reverses these adverse effects and extends lifespan, positioning the KDM5A/FABP4 axis as a ...
Rifeng Gao, Lifeng Liang, Ling Yang, Chunyu Lyu, Yang Lyu, Weijun Yang, Jiaran Shi, Wei Wei, Jiahui Cheng, Xiaolei Sun, Xian Zhu, Chao Chen, Xiaoting Xu, Jianchuang Qi, Wenli Li, Yizhe Zhang, Xiao Zhang, Yan Zhou, Aiqiang Dong, Juntao Chen, Bo Li, Kun Yang   +21 more
wiley   +1 more source

Population-Based Incidence of Guillain-Barré Syndrome During Mass Immunization With Viral Vaccines: A Pooled Analysis. [PDF]

Front Immunol, 2022
Wang F, Wang D, Wang Y, Li C, Zheng Y, Guo Z, Liu P, Zhang Y, Wang W, Wang Y, Hou H.   +10 more
europepmc   +1 more source

Implications of viral transmitted/founder (T/F) dynamics on vaccine development [PDF]

, 2020
Alexander I. Mosa
openalex   +1 more source

⁠Engineering Adaptive Immunity in 3D: A Patient‐Specific Lymphoid Model Using Stromal Networks and Peripheral Blood Mononuclear Cells

Advanced Science, EarlyView.
This study presents a 3D lymphoid tissue model engineered from adipose‐derived stem cells differentiated into fibroblastic reticular cell–like networks and co‐cultured with immune cells. The engineered system successfully generates antigen‐specific antibodies and cytokine responses, providing a platform for studying adaptive immunity, vaccine efficacy,
Mei ElGindi, Shaza Karaman, Jeremy Teo
wiley   +1 more source

A live-attenuated viral vector vaccine protects mice against lethal challenge with Kyasanur Forest disease virus [PDF]

, 2021
Bharti Bhatia, Kimberly Meade‐White, Elaine Haddock, Friederike Feldmann, Andrea Marzi, Heinz Feldmann   +5 more
openalex   +1 more source

A Quantum Framework for Protein Binding‐Site Structure Prediction on Utility‐Level Quantum Processors

Advanced Science, EarlyView.
This study presents a hybrid quantum‐classical framework for accurate prediction of protein structures on utility‐level quantum processors. We evaluate the practical application of the Variational Quantum Eigen‐solver (VQE) in protein structure prediction and demonstrate its superiority over state‐of‐the‐art deep learning methods in molecular docking ...
Yuqi Zhang, Yuxin Yang, William Martin, Kingsten Lin, Zixu Wang, Cheng‐Chang Lu, Weiwen Jiang, Ruth Nussinov, Joseph Loscalzo, Qiang Guan, Feixiong Cheng   +10 more
wiley   +1 more source