Results 151 to 160 of about 1,560,419 (396)
Архивъ внутренней медицины, 2017 The prevalence of Anelloviridae virus is high among population in many countries. The hepatotropic and hepatopathogenic features were confirmed in some genotypes of this family.
I. A. Morozov +6 more
doaj +1 more source
Matrix and Backstage: Cellular Substrates for Viral Vaccines
Viruses, 2014 Vaccines are complex products that are manufactured in highly dynamic processes. Cellular substrates are one critical component that can have an enormous impact on reactogenicity of the final preparation, level of attenuation of a live virus, yield of ...
I. Jordan, V. Sandig
semanticscholar +1 more source
Geometric Adjustment of T Cell‐Sensitive Nanorobots for Enhanced Stability
Advanced Healthcare Materials, EarlyView.For the long‐term use of live dendritic cell (DC)‐based vaccines, nano bone marrow dendritic cell (BMDC) originated T cell activators (nano‐BOTs) are synthesized. The geometric properties of nanoparticles are precisely modulated, enhancing their stability and T cell activation capacity.
Yoojin Lee +11 more
wiley +1 more source
A temperature sensitive live-attenuated canine influenza virus H3N8 vaccine [PDF]
, 2017 Canine influenza is a respiratory disease of dogs caused by canine influenza virus (CIV). CIV subtypes responsible for influenza in dogs include H3N8, which originated from the transfer of H3N8 equine influenza virus to dogs; and the H3N2 CIV, which is ...
Chauché, Caroline +8 more
core +1 more source
Clinical Advances in Viral-Vectored Influenza Vaccines
Vaccines, 2018 Influenza-virus-mediated disease can be associated with high levels of morbidity and mortality, particularly in younger children and older adults. Vaccination is the primary intervention used to curb influenza virus infection, and the WHO recommends ...
Sarah Sebastian, T. Lambe
semanticscholar +1 more source
Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In Vivo mRNA Delivery
Advanced Healthcare Materials, EarlyView.Lipid nanoparticles (LNPs) have rapidly become the delivery system of choice for RNA therapeutics. Here, a rational design approach is taken to improve the effectiveness of LNPs based on an ionizable thioether lipid library. The incorporation of unsaturated tails and bulkier, hydrophobic head groups significantly enhances their functionality and ...
Eleni Samaridou +4 more
wiley +1 more source
Recent advances in therapeutic modalities and vaccines to counter COVID-19/SARS-CoV-2
Human Vaccines & Immunotherapeutics, 2020 The novel coronavirus disease (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has rapidly spread across the world. This resulted an alarming number of fatalities with millions of confirmed infected cases, pretending ...
Muhammad Bilal, Hafiz M. N. Iqbal
doaj +1 more source
From Viral Vaccines to Messenger RNA Vaccines
Pakistan Journal of Medicine and Dentistry, 2020 Today, the swiftness of epidemics of infectious disease is alarming. To date vaccines have been an enormous success for not only preventing but completely eradicating a number of malicious infectious disease like small pox, rubella, mumps, measles and ...
Saeeda Baig, Zoha Asghar
doaj +1 more source
Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting
Advanced Materials, EarlyView.CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu +4 more
wiley +1 more source
The role of research in viral disease eradication and elimination programs: Lessons for malaria eradication [PDF]
, 2011 By examining the role research has played in eradication or regional elimination initiatives for three viral diseases-smallpox, poliomyelitis, and measles-we derive nine cross-cutting lessons applicable to malaria eradication.
Breman, JG +6 more
core +1 more source