Results 201 to 210 of about 349,023 (332)

Novel Swelling‐Lytic Cell Death Triggered by Cargo‐Free Ionizable Lipid Nanoparticles

Advanced Science, EarlyView.
A cargo‐free ionizable lipid nanoparticles (ipLNP) is found to induce broad swelling‐lytic cell death across multiple cell types. Cell death may be associated with lysosome membrane destabilization, involving ROS increase, lipid peroxidation, and GSDME cleavage.
Junjun Wu, Zhennan Zhao, Hongsheng Wu, Sihuang Lin, Lin Huang, Guanjie Chen, Yi Yang, Hong Wang, Huijie Yan, Yonghui Shi, Liuyu Zhu, Guosheng Hu, Liling Zheng, Songying Ouyang   +13 more
wiley   +1 more source

Using the Past to Maximize the Success Probability of Future Anti-Viral Vaccines. [PDF]

Vaccines (Basel), 2020
Serwer P.
europepmc   +1 more source

Patterns of viral replication correlate with outcome in simian immunodeficiency virus (SIV)-infected macaques: effect of prior immunization with a trivalent SIV vaccine in modified vaccinia virus Ankara

, 1996
Vanessa M. Hirsch, Thomas R. Fuerst, Gerd Sutter, Miles W. Carroll, Lijuan Yang, S Goldstein, M. Piatak, William R. Elkins, W. Gregory Alvord, David C. Montefiori, Bernard Moss, Jeff Lifson   +11 more
openalex   +1 more source

Physicochemical Characterization of Influenza Viral Vaccine Loaded Surfactant Vesicles [PDF]

, 2003
S. C. Chattaraj, Sudip Das
openalex   +1 more source

Biomolecular Interaction Prediction: The Era of AI

Advanced Science, EarlyView.
This review offers a thorough examination of recent progress in deep learning for predicting biomolecular interactions, including those involving proteins, nucleic acids, and small molecules. It covers data processing strategies, representative model architectures, and evaluation metrics, while highlighting current methodological limitations.
Haoping Wang, Xiangjie Meng, Yang Zhang
wiley   +1 more source

The Changing Epidemiology of Herpes Simplex Virus Type 1 Infection: The Associated Effects on the Incidence of Ocular Herpes

Archives of Razi Institute, 2016
Herpes simplex virus type 1 (HSV-1) with a worldwide distribution has been reported in all human populations, resulting in a clinical spectrum of infections.
Abedi Kiasari, B., Zare Tooranposhti, Z.
doaj  

Rotavirus NSP4 Acts as a Viral Enterotoxin to Induce Diarrhea and is a Potential Target for Rotavirus Vaccines

, 1998
Alexandra W. C. Einerhand
openalex   +1 more source

Harnessing co-operative immune augmentation by contact allergens to enhance the efficacy of viral vaccines. [PDF]

Contact Dermatitis, 2020
Cunningham LS, McFadden JP, Basketter DA, Ferguson FJ, White IR, Kimber I.   +5 more
europepmc   +1 more source

Rapid and Ultra‐Sensitive SARS‐CoV‐2 Subgenomic RNA Detection Using Single‐Molecule With a Large Transistor‐SiMoT Bioelectronic Platform

Advanced Electronic Materials, EarlyView.
The single‐molecule with a large transistor‐SiMoT is proposed for the detection of the subgenomic RNA of SARS‐CoV‐2, achieving a diagnostic sensitivity of 98.0% and a specificity of 87.8%. The SiMoT technology, currently at TRL‐5, is suitable for point‐of‐care settings and delivers the result to the end user in 30 min.
Eleonora Macchia, Anna Maria D'Erchia, Mariapia Caputo, Angelica Bianco, Claudia Leoni, Francesca Intranuovo, Cecilia Scandurra, Lucia Sarcina, Cinzia Di Franco, Paolo Bollella, Gaetano Scamarcio, Luisa Torsi, Graziano Pesole   +12 more
wiley   +1 more source

Recombinant Listeria monocytogenes as a live vaccine vehicle for the induction of protective anti-viral cell-mediated immunity.

, 1995
Hao Shen, Mark K. Slifka, Mehrdad Matloubian, Eric R. Jensen, Rafi Ahmed, Jeff F. Miller   +5 more
openalex   +1 more source