Results 111 to 120 of about 657,629 (304)
Clinically translatable mitochondrial gene therapy in muscle using tandem mtZFN architecture
EMBO Molecular MedicineMutations in the mitochondrial genome (mtDNA) often lead to clinical pathologies. Mitochondrially-targeted zinc finger nucleases (mtZFNs) have been successful in reducing the levels of mutation-bearing mtDNA both in vivo and in vitro, resulting in a ...
Pavel A Nash +11 more
doaj +1 more source
Advanced Functional Materials, EarlyView.MAMAWEL is introduced as the first calibration‐free potentiometric sensor for at‐home mastitis diagnosis. By measuring the sodium‐to‐potassium ratio in breast milk, the device reliably differentiates between healthy and mastitis‐affected samples with less than 10% error.
Ali Soleimani +9 more
wiley +1 more source
Genetic Diversity of the Hepatitis C Virus Among Patients with HIV in EECA Countries
VirusesAgainst the backdrop of active efforts to combat HCV worldwide with the help of DAAs, knowledge of the genetic diversity of HCV in the general population and in groups most at risk of infection is becoming increasingly important.
Vasiliy E. Ekushov +24 more
doaj +1 more source
50. Long-Term Follow-Up of Diabetic Dogs Treated with Adeno-Associated Viral Vectors Encoding for Insulin and Glucokinase [PDF]
, 2016 Verónica Jiménez +14 more
openalex +1 more source
Advanced Functional Materials, EarlyView.Two kinds of self‐assembled RNA micelles were used to co‐deliver synergistic siRNA and nucleoside analogues for the treatment of colorectal cancer lung metastases. Near‐complete elimination of lung cancer metastases was confirmed in an orthotopic lung metastasis model constructed using human colorectal cancer lung metastases patient surgical samples to
Kai Jin +4 more
wiley +1 more source
An Adeno-Associated Viral Vector Capable of Penetrating the Mucus Barrier to Inhaled Gene Therapy [PDF]
, 2018 Gregg A. Duncan +12 more
openalex +1 more source
A live-attenuated viral vector vaccine protects mice against lethal challenge with Kyasanur Forest disease virus [PDF]
, 2021 Bharti Bhatia +5 more
openalex +1 more source
Advanced Functional Materials, EarlyView.Tumor‐tropic human mesenchymal stem cells (hMSCs) were used as delivery vehicles for magnetotheranostic gold–iron oxide nanoflowers. Magnetic particle imaging of the iron component demonstrated widespread intratumoral distribution and sustained retention in contrast to injection of naked nanoflowers.
Behnaz Ghaemi +7 more
wiley +1 more source
Advanced Functional Materials, EarlyView.xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat +11 more
wiley +1 more source
The viral content ratio between abdomen and head is informative of the relative efficiency with which Bemisia tabaci populations transmit begomoviruses. [P.12] [PDF]
, 2015 Begomoviruses (family Geminiviridae) are transmitted by the whitefly Bemisia tabaci in a circulative non propagative manner. B. tabaci is a species complex composed of at least 24 morphocryptic species which differ in host range, insecticide resistance ...
Gargani, Daniel +3 more
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