Results 191 to 200 of about 657,629 (304)

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Advanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang   +8 more
wiley   +1 more source

ShH10 viral vector for safe, efficient, and selective transduction of inner ear supporting cells. [PDF]

Dev Biol
Bertken YJ, Kim Y, Llamas J, Beck A, Nagiel A, Gnedeva K.   +5 more
europepmc   +1 more source

Understanding the Consequences of Soil Amendments on Host Selection by a Maize Viral Vector (CicadulinambilaNaudé)

, 2016
O. E. V. Magenya, J. M. Mueke
openalex   +1 more source

Excess antisense RNA from infectious recombinant SV40 fails to inhibit expression of a transfected, interferon-inducible gene [PDF]

, 1988
Kerr, I M, Kerr, S M, Stark, G R
core   +1 more source

Construction of a Multitissue Cell Atlas Reveals Cell‐Type‐Specific Regulation of Molecular and Complex Phenotypes in Pigs

Advanced Science, EarlyView.
This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen, Houcheng Li, Jinyan Teng, Zhen Wang, Xiaolu Qu, Zhe Chen, Xiaodian Cai, Haonan Zeng, Zhonghao Bai, Jinghui Li, Xiangchun Pan, Leyan Yan, Fei Wang, Lin Lin, Yonglun Luo, Goutam Sahana, Mogens Sandø Lund, Maria Ballester, Daniel Crespo‐Piazuelo, Peter Karlskov‐Mortensen, Merete Fredholm, Alex Clop, Marcel Amills, Crystal Loving, Christopher K. Tuggle, Ole Madsen, Jiaqi Li, Zhe Zhang, George E. Liu, Jicai Jiang, Lingzhao Fang, Guoqiang Yi   +31 more
wiley   +1 more source

Translocating shRNA: a novel approach to RNA interference with Newcastle disease virus as viral vector. [PDF]

J Gen Virol
Koh WC, Yusoff K, Song AA, Saad N, Tan TK, Cheow PS, Chia SL.   +6 more
europepmc   +1 more source

1336. Quantitative Comparison of Non-Viral Gene Delivery Vectors: Model Analysis of Kinetic Intracellular Trafficking Events [PDF]

, 2002

openalex   +1 more source

Sabotaged Integral HSC Heterogeneity Underlies Essential Thrombocythemia Development

Advanced Science, EarlyView.
Single‐cell RNA sequencing (scRNA‐seq) maps how distinct driver mutations remodel hematopoietic stem cell (HSC) programs across essential thrombocythemia (ET). Comparative analysis uncovers both shared and subtype‐specific molecular signatures, identifies a triple‐negative (TN)‐associated HSC population enriched with malignant traits, and reveals the ...
Jingyuan Tong, Di Wang, Haoze Song, Ting Sun, Yanhong Zhao, Wenjing Gu, Lexuan Lin, Yitong Zhao, Yipeng Liang, Xu Jin, Rongfeng Fu, Mankai Ju, Jie Gao, Jinfa Ma, Chengjie Gao, Anqi Zhang, Zhijian Xiao, Erlie Jiang, Renchi Yang, Shihui Ma, Lei Zhang, Lihong Shi   +21 more
wiley   +1 more source

Development of SARS-CoV-2 as a viral vector: A novel intranasal bivalent vaccine for SARS-CoV-2 and RSV. [PDF]

Sci Adv
Xu J, Chamblee M, Jiang F, Kc M, Hsu CC, Thongpan I, Chen P, Zhang Y, Chiu CT, Shamseldin MM, Amer HM, Liang X, Amer AO, Boyaka PN, Cormet-Boyaka E, Peeples ME, Li J.   +16 more
europepmc   +1 more source

A Capsid-Modified Adenovirus Vector Devoid of All Viral Genes: Assessment of Transduction and Toxicity in Human Hematopoietic Cells [PDF]

, 2001
Hartmut Stecher, Dmitry M. Shayakhmetov, George Stamatoyannopoulos, André Lieber   +3 more
openalex   +1 more source