Results 251 to 260 of about 2,924,139 (391)

Adeno-associated viral vector resource for the RNA-targeting Cas13d: A comparison of high-fidelity variants, DjCas13d and hfCas13d. [PDF]

Mol Ther Methods Clin Dev
Back F, Sandoval A, Vu LM, Hong VM, Bhaskara A, Rodriguez SR, O'Brien JT, Kolber BJ, Kroener S, Ploski JE.   +9 more
europepmc   +1 more source

Lnc‐HZ05 Suppresses Trophoblast Cell Migrasome Formation by Disrupting TGFβ2 Pathway in Unexplained Recurrent Miscarriage

Advanced Science, EarlyView.
TGFβ2 signaling‐mediated migration/invasion and migrasome formation are suppressed in recurrent miscarriage (RM) versus healthy control villous tissues and are negatively associated with unexplained RM. In mechanism, TGFβ2 promotes trophoblast cell migration/invasion and migrasome formation, all of which are suppressed by lnc‐HZ05. In details, lnc‐HZ05
Weina Chen, Ying Zhang, Zimeng Zhao, Yang Yang, Geng Guo, Yi Sun, Tao Zhang, Zhihong Zhang, Liqin Zeng, Wenxin Huang, Qingjun Shen, Ruining Han, Zhaohui He, Depeng Zhao, Huidong Zhang   +14 more
wiley   +1 more source

Immunogenicity and Contraceptive Potential of a Classical Swine Fever Viral Vector Live Vaccine Strain Containing Pig Gonadotropin-Releasing Hormone. [PDF]

Vaccines (Basel)
An DJ, Shin JH, Choe S, Lee YH, Jang MK, An BH, Park GN, Cho YS, Chang KS.   +8 more
europepmc   +1 more source

An investigation of excipients for a stable Orf viral vector formulation. [PDF]

Virus Res, 2023
Eilts F, Harsy YMJ, Lothert K, Pagallies F, Amann R, Wolff MW.   +5 more
europepmc   +1 more source

987. Effects of Promoter and Viral Dose on AAV Vector-Mediated Gene Expression, Efficacy and Survival in a Mouse Model of Niemann-Pick A Disease [PDF]

, 2007

openalex   +1 more source

DKK3 Initially Preserves Acinar Integrity Through MEK‐Fos Signaling, but Later Switches to an Oncogenic Role in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic cancer, the protein DKK3 is found to play a complex role: it initially slows early tumor growth but later promotes tumor aggressiveness. DKK3 expression evolves during progression and drives cancer severity by orchestrating cellular and molecular signaling pathways.
Dharini Srinivasan, Elodie Roger, Lukas Perkhofer, Eleni Zimmer, Thomas F.E. Barth, Julia P. Mosler, Anna Härle, Stephanie E. Weissinger, Nadine T. Gaisa, Peter Möller, Nico Fischer, Chantal Allgöwer, J.‐Matthias Löhr, Dirk Grimm, Thomas Seufferlein, Stefan Liebau, Ninel Azoitei, Michael K. Melzer, Frank Arnold, Johann Gout, Alexander Kleger   +20 more
wiley   +1 more source

Towards enhancing photostability and adeno-associated viral vector delivery for genetically encoded plasma fluorescent labels. [PDF]

Neurophotonics
Knak PG, Vittani M, Lee AB, Nedergaard L, Elleholm NV, Wang X, Bojarowska Z, Martens MC, Konno A, Hirai H, Nedergaard M, Hirase H.   +11 more
europepmc   +1 more source

Type II Alveolar Epithelial Cells Promote Sepsis‐Induced Immunosuppression in Alveolar Macrophages via Exosomal lncRNA Rmrp Release

Advanced Science, EarlyView.
The S100A4/STAT3 axis promotes Rmrp transcription in AEC‐IIs and Rmrp expression in AEC‐II‐derived exosomes. Upon entry into AMs, Rmrp binds to and blocks the ubiquitination and degradation of ZFP36. Increased ZFP36 induced Pfkfb3 mRNA decay by binding to AREs in the 3′ UTR, curbing glycolysis and immune responses of AMs and aggravating SII and ...
Chengxi Liu, Weixia Xuan, Song Cao, Huayun Jia, Qian Wu, Xiaowu Tan, Qijie Wang, Xiaojun Li, Lisha Ding, Yaru Xiong, Meiyun Zhao, Longcheng Zheng, Yunzhu Xi, Jianhua Tan, Rong Li, Xulong Zhang, Wenjie Liu, Xu Wu   +17 more
wiley   +1 more source

A breath of fresh air: targeted non-viral in vivo gene correction in the mammalian lung

Signal Transduction and Targeted Therapy
Jixin Liu, Dirk Grimm
doaj   +1 more source

Development and Characterization of Adeno-Associated Virus-Loaded Coaxial Electrospun Scaffolds for Potential Viral Vector Delivery. [PDF]

Polymers (Basel)
Zhang H, Zhou B, Dong W, Song Y, Hu Q, Zhang H, Yu M, Zhu G, Sun Y, Feng J.   +9 more
europepmc   +1 more source