Results 281 to 290 of about 2,747,170 (398)

Adeno-associated viral vector-mediated gene transfer results in long-term enzymatic and functional correction in multiple organs of Fabry mice

, 2001
Sung‐Chul Jung, Ina Han, Advait Limaye, Ruian Xu, Monique P. Gelderman, Patricia M. Zerfas, Tirumalai Kamala, Gary J. Murray, Matthew J. During, Roscoe O. Brady, Pankaj Qasba   +10 more
openalex   +1 more source

1359. Glioma Therapy Using Sindbis Vectors Encoding Viral Fusogenic Membrane Glycoprotein [PDF]

, 2002

openalex   +1 more source

Trends in Viral Vector-Based Vaccines for Tuberculosis: A Patent Review (2010-2023). [PDF]

Vaccines (Basel)
Santos LC, Fernandes AMS, Alves IA, Serafini MR, Silva LDSE, de Freitas HF, Leite LCC, Santos CC.   +7 more
europepmc   +1 more source

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

Advanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang, Xing Chang, Chun Li, Jing Gao, Zhijiang Guo, Haowen Zhuang, Lingjun Wang, Yusheng Huang, Wei Wang, Chao Li, Qingyong He   +10 more
wiley   +1 more source

1336. Quantitative Comparison of Non-Viral Gene Delivery Vectors: Model Analysis of Kinetic Intracellular Trafficking Events [PDF]

, 2002

openalex   +1 more source

LincNEAT1 Encoded‐NEAT1‐31 Promotes Phagocytosis by Directly Activating the Aurora‐A–PI3K–AKT Pathway

Advanced Science, EarlyView.
LincNEAT1 Encoded‐NEAT1‐31 micropeptide directly binds with Aurora‐A and enhanced AKT pathways to pormotes phagocytosis against multi cancer cells. Abstract Macrophages play vital roles in innate and adaptive immunity, and their essential functions are mediated by phagocytosis and antigen presentation.
Jie Li, Jing Zhang, Xixi Li, Xin Liu, Bo Zeng, Jiayue Luo, Huijin Wang, Hanbing Zhang, Xinya Gao   +8 more
wiley   +1 more source

287. Targeted Gene Delivery to the Central Nervous System by Adeno Associated Viral Vectors [PDF]

, 2002

openalex   +1 more source

Use of patient-derived organotypic tumor spheroids for testing of viral vector gene therapy in combination with checkpoint blockade. [PDF]

Mol Ther Oncol
Domingues ACM, de Oliveira SB, Tessarollo NG, Lepique AP, Rodrigues O, Sharova T, Lawless A, Li D, Basnet M, Boland GM, Cohen S, Jenkins RW, Strauss BE.   +12 more
europepmc   +1 more source

Genetics‐Based Targeting Strategies for Precise Neuromodulation

Advanced Science, EarlyView.
In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He, Zhidong Wei, Jianda Xu, Fei Jin, Tong Li, Lili Qian, Juan Ma, Weiying Zheng, Negar Javanmardi, Ting Wang, Kangjian Sun, Zhang‐Qi Feng   +11 more
wiley   +1 more source

532. Systemic Delivery of Therapeutic Genes by a Sendai Virus Based Negative-Strand RNA Viral Vector [PDF]

, 2002

openalex   +1 more source