Results 31 to 40 of about 1,876,696 (266)

Relevant Day/Night Temperatures Simulating Belgian Summer Conditions Reduce Japanese Encephalitis Virus Dissemination and Transmission in Belgian Field-Collected Culex pipiens Mosquitoes

open access: yesViruses, 2023
Japanese encephalitis virus (JEV), a zoonotic mosquito-borne Flavivirus, can be considered an emerging infectious disease. Therefore, vector competence studies with indigenous mosquitoes from regions where JEV is not yet endemic are of great importance ...
Claudia Van den Eynde   +3 more
doaj   +1 more source

Can insecticide-treated netting provide protection for Equids from Culicoides biting midges in the United Kingdom?

open access: yesParasites & Vectors, 2015
Background Biting midges of the genus Culicoides Latreille, 1809 (Diptera: Ceratopogonidae) cause a significant biting nuisance to equines and are responsible for the biological transmission of African horse sickness virus (AHSV).
Tiffany Baker   +6 more
doaj   +1 more source

Current Streptococcus Pneumoniae Serotypes in Sverdlovsk Region in 2020–2021

open access: yesЭпидемиология и вакцинопрофилактика, 2023
Relevance. Studying the spread of individual S. pneumoniae serotypes is of special epidemiologic and clinical importance. Sverdlovsk Region with the 20% proportion of community­-acquired pneumonia and its proportion among the causes of mortality of up to
E. V. Bolgarova   +6 more
doaj   +1 more source

Foxtail mosaic virus: a new viral vector for protein expression in cereals [PDF]

open access: yes, 2018
Rapid and cost-effective virus-derived transient expression systems for plants are invaluable in elucidating gene function. These are particularly useful in the case of plant species for which transformation-based methods are either not yet developed, or
Stéphane Bieri   +13 more
core   +1 more source

Adenovirus-based gene therapy approaches for hemophilia B [PDF]

open access: yes, 2012
Gene therapy can be used to treat devastating inherited diseases, especially diseases and patients that are not suitable for a conventional cure. The blood clotting disorder hemophilia is one of the most extensively studied monogenetic diseases in gene ...
Zhang, Wenli
core   +1 more source

An optimised method for the production of MERS-CoV spike expressing viral pseudotypes [PDF]

open access: yes, 2015
The production and use of pseudotyped viral particles is widely established for many viruses, and applications in the fields of serology and vaccine development are manifold.
Ferrara, Francesca   +5 more
core   +1 more source

Cytomegalovirus replicon-based regulation of gene expression in vitro and in vivo [PDF]

open access: yes, 2011
There is increasing evidence for a connection between DNA replication and the expression of adjacent genes. Therefore, this study addressed the question of whether a herpesvirus origin of replication can be used to activate or increase the expression of ...
Mohr, Hermine   +47 more
core   +2 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Intratumoral Immunization by p19Arf and Interferon-β Gene Transfer in a Heterotopic Mouse Model of Lung Carcinoma

open access: yesTranslational Oncology, 2016
Therapeutic strategies that act by eliciting and enhancing antitumor immunity have been clinically validated as an effective treatment modality but may benefit from the induction of both cell death and immune activation as primary stimuli.
João Paulo Portela Catani   +8 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

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