Results 61 to 70 of about 2,924,139 (391)
Engineering multiple levels of specificity in an RNA viral vector [PDF]
, 2020 Synthetic molecular circuits could provide powerful therapeutic capabilities, but delivering them to specific cell types and controlling them remains challenging.
Chong, Lucy S. +4 more
core +1 more source
Is Viral Vector Gene Delivery More Effective Using Biomaterials?
Advanced Healthcare Materials, 2020 Gene delivery has been extensively investigated for introducing foreign genetic material into cells to promote expression of therapeutic proteins or to silence relevant genes.
Yi Wang +7 more
semanticscholar +1 more source
Parasites & Vectors, 2015 Background Biting midges of the genus Culicoides Latreille, 1809 (Diptera: Ceratopogonidae) cause a significant biting nuisance to equines and are responsible for the biological transmission of African horse sickness virus (AHSV).
Tiffany Baker +6 more
doaj +1 more source
Current Streptococcus Pneumoniae Serotypes in Sverdlovsk Region in 2020–2021
Эпидемиология и вакцинопрофилактика, 2023 Relevance. Studying the spread of individual S. pneumoniae serotypes is of special epidemiologic and clinical importance. Sverdlovsk Region with the 20% proportion of community-acquired pneumonia and its proportion among the causes of mortality of up to
E. V. Bolgarova +6 more
doaj +1 more source
Zika virus infection in semen: Effect on human reproduction [PDF]
, 2017 Unique among vector-borne flaviviruses, Zika virus can infect testis and male genital tract, can persist in semen for months after symptoms onset, and be sexually transmitted.
Barzon, Luisa +2 more
core +1 more source
Genome editing technologies to fight infectious diseases [PDF]
, 2017 Genome editing by programmable nucleases represents a promising tool that could be exploited to develop new therapeutic strategies to fight infectious diseases.
Barzon, Luisa +2 more
core +1 more source
Viral Vector Vaccines against Bluetongue Virus
Microorganisms, 2020 Bluetongue virus (BTV), the prototype member of the genus Orbivirus (family Reoviridae), is the causative agent of an important livestock disease, bluetongue (BT), which is transmitted via biting midges of the genus Culicoides.
L. Jiménez-Cabello +6 more
semanticscholar +1 more source
In vivo genetic manipulation of inner ear connexin expression by bovine adeno-Associated viral vectors [PDF]
, 2017 We have previously shown that in vitro transduction with bovine adeno-associated viral (BAAV) vectors restores connexin expression and rescues gap junction coupling in cochlear organotypic cultures from connexin-deficient mice that are models DFNB1 ...
Campioni, Matteo +7 more
core +1 more source
Surface immobilization of hexa-histidine-tagged adeno-associated viral vectors for localized gene delivery. [PDF]
, 2010 Adeno-associated viral (AAV) vectors, which are undergoing broad exploration in clinical trials, have significant promise for therapeutic gene delivery because of their safety and delivery efficiency.
Bethi, SR +5 more
core +2 more sources
Engineering influenza viral vectors [PDF]
Bioengineered, 2013 The influenza virus is a respiratory pathogen with a negative-sense, segmented RNA genome. Construction of recombinant influenza viruses in the laboratory was reported starting in the 1980s. Within a short period of time, pioneer researchers had devised methods that made it possible to construct influenza viral vectors from cDNA plasmid systems. Herein,
Li, Junwei +2 more
openaire +2 more sources