Results 81 to 90 of about 2,747,170 (398)
Tick-borne encephalitis virus (TBEV) is a flavivirus transmitted by ticks. Serological screenings in animals are performed to estimate the prevalence and distribution of TBEV.
Gabrielle Trozzi+5 more
doaj +1 more source
PLASMD BEARING A CDNA COPY OF THE GENOME OF BOVINE VIRAL DIARRHEA VIRUS, CHIMERIC DERIVATIVES THEREOF, AND METHOD OF PRODUCING AN INFECTIOUS BOVINE WRAL DARRHEAVIRUS USING SAD PLASMID [PDF]
A plasmid bearing a cDNA copy of the genome of bovine viral diarrhea virus (BVDV), chimeric derivatives of the plasmid and a method of producing an infectious bovine viral diarrhea virus using the plasmid are disclosed. The invention relates to a plasmid
Donis, Ruben O., Vassilev, Ventzislav B.
core +1 more source
Zika virus infection in semen: Effect on human reproduction [PDF]
Unique among vector-borne flaviviruses, Zika virus can infect testis and male genital tract, can persist in semen for months after symptoms onset, and be sexually transmitted.
Barzon, Luisa+2 more
core +1 more source
An engineered viral vector of bacteriophage T4 linked to AAV delivers large payloads of genes and proteins into human cells. Development of safe and efficient nanoscale vehicles that can deliver large molecular cargos into human cells could transform ...
Jingen Zhu+6 more
semanticscholar +1 more source
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao+7 more
wiley +1 more source
The advent of reverse genetic approaches to manipulate the genomes of both positive (+) and negative (-) sense RNA viruses allowed researchers to harness these genomes for basic research. Manipulation of positive sense RNA virus genomes occurred first largely because infectious RNA could be transcribed directly from cDNA versions of the RNA genomes ...
Mark Mogler, Kurt I Kamrud
openaire +2 more sources
Viral Vectors for Plant Genome Engineering [PDF]
Recent advances in genome engineering (GE) has made it possible to precisely alter DNA sequences in plant cells, providing specifically engineered plants with traits of interest. Gene targeting efficiency depends on the delivery-method of both sequence-specific nucleases and repair templates, to plant cells.
Shahid Mansoor, Syed Shan-e-Ali Zaidi
openaire +3 more sources
Gene therapy for diabetes : lentiviral expression of insulin in liver cells [PDF]
University of Technology, Sydney. Faculty of Science.Type 1 diabetes mellitus (T1D) is caused by the autoimmune destruction of the insulin producing pancreatic beta (β)-cells.
Gatt, PN
core
Technique of retinal gene therapy: delivery of viral vector into the subretinal space
PurposeSafe and reproducible delivery of gene therapy vector into the subretinal space is essential for successful targeting of the retinal pigment epithelium (RPE) and photoreceptors.
Kanmin Xue+3 more
semanticscholar +1 more source
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi+5 more
wiley +1 more source