Results 121 to 130 of about 285,022 (264)

Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy

Advanced Materials, EarlyView.
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla, Jacqueline J. Li, Qunzhou Zhang, Korey Patwari, Shihong Shi, Hannah M. Yamagata, Ryann A. Joseph, Briyanna N. Hymms, Sridatta V. Teerdhala, Emily Fitzgerald, Ori Z. Chalom, Kushol Gupta, Mohamad‐Gabriel Alameh, Drew Weissman, Anh D. Le, Michael J. Mitchell   +15 more
wiley   +1 more source

Highly Entangled Bottlebrush Polymer Networks

Advanced Materials, EarlyView.
Bottlebrush polymers are difficult to entangle, enabling ultrasoft yet brittle networks. We report highly entangled bottlebrush elastomers that remain ultrasoft (∼1 kPa) yet stretch to ∼1800% and exhibit exceptional fatigue resistance. Their intrinsic fatigue strength—fatigue threshold normalized by modulus—surpasses that of highly entangled linear ...
Myoeum Kim, Baiqiang Huang, Shiwang Cheng, Li‐Heng Cai   +3 more
wiley   +1 more source

Colonic Ischemia in a Patient With Pemphigus Vulgaris: Coincidence or Causation. [PDF]

Cureus
Joshi R, Tsering D, Krueger E, Wall N, Anis M, Miller TA, Cohen S.   +6 more
europepmc   +1 more source

Anomalous Crystallinity and Magnetism in Chemically Disordered Coherent Heterostructures

Advanced Materials, EarlyView.
Coherent isostructural high‐entropy oxide heterostructures are realized despite remarkable >5% interfacial lattice distortion. The resulting buried interface exhibits abrupt valence reconstruction which contributes to 2 × enhanced exchange bias in the heterostructure relative to constituent layers, demonstrating how chemical disorder enabled anomalous ...
Saeed S. I. Almishal, Sai Venkata Gayathri Ayyagari, Aaron Pearre, Pat Kezer, Matthew Furst, Christina M. Rost, Binghai Yan, Nasim Alem, Timothy Charlton, Zhiqiang Mao, John T. Heron, Jon‐Paul Maria   +11 more
wiley   +1 more source

Alert on a Novel South American Bat Coronavirus with a Furin-Cleavage Site: A One Health Early Warning. [PDF]

Rev Soc Bras Med Trop
Santana LADM, Floresta LG, Alves ÊVM, Barbosa BF, Couto GR, Santos MALD, Moura PHM, Silva DMRR, Barreto MDS, Repeke CEP, Amaral RCD, Silva VKDS, Trento CL, Takeshita WM, Correia D, Gopalsamy RG, Borges LP.   +16 more
europepmc   +1 more source

Pocahontas folio, Virginia-West Virginia [PDF]

, 1896
openaire   +1 more source

Optoelectronic Nanofluidic Neural Networks for Ionic Computing

Advanced Materials, EarlyView.
An ion‐based optoelectronic nanofluidic memristor enables neuromorphic computing in aqueous environments. With tunable ionic memory and multimodal synaptic plasticity, it realizes densely connected ionic neural networks capable of image classification, motion prediction, logic computation, and real‐time in‐sensor computing, advancing fully connected ...
Yaxin Huang, Zhiyuan Du, Changjin Wu, Binglin Zeng, Yingnan Cao, Mingliang Li, Liren Zhang, Qingxin Guo, Chao Huang, Can Li, Jinyao Tang   +10 more
wiley   +1 more source

Determinants of cardiorespiratory fitness after successfully reperfused ST-elevation myocardial infarction. [PDF]

Curr Probl Cardiol
Hogwood AC, Smarż K, Golino M, Tysarowski M, Canada JM, Zaborska B, Dziekan-Wisławska K, Zioło J, West JD, Jaxa-Chamiec T, Kontos E, Barron AM, Mbualungu J, Marchetta M, Lopez R, Moroni F, Arena R, Tassell BV, Abbate A.   +18 more
europepmc   +1 more source

De Novo Autogenic Engineered Living Functional Materials

Advanced Materials, EarlyView.
A versatile platform for de novo autogenic engineered living materials is presented, leveraging protein mining, computational modeling, and synthetic biology. By reprogramming the Escherichia coli curli machinery with β‐solenoid proteins from non‐model bacteria, macroscopic biomaterials with enhanced mechanical properties, UV‐C irradiation protection ...
Hoda M. Hammad, Seth Swarnadeep, Erin C. Jackson, Nicolas Burns, Hongyu Wang, Harrison Priode, Robert B. Moore, Sanket Deshmukh, Avinash Manjula‐Basavanna, Anna M. Duraj‐Thatte   +9 more
wiley   +1 more source

The use of memantine for prevention of Alzheimer's disease: Pilot feasibility study rationale and protocol. [PDF]

Contemp Clin Trials Commun
Arp AM, Bloom GS, D'Abreu A, Fansler A, Meegan K, Ratcliffe S, Kapur J, Manning C.   +7 more
europepmc   +1 more source