Results 221 to 230 of about 1,978,611 (289)

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

open access: yesAdvanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann   +26 more
wiley   +1 more source

Correction: Margaryan et al. The Stem Cell Phenotype of Aggressive Breast Cancer Cells. <i>Cancers</i> 2019, <i>11</i>, 340. [PDF]

open access: yesCancers (Basel)
Margaryan NV   +8 more
europepmc   +1 more source

Isolation and characterization of four novel Vibrio parahaemolyticus bacteriophages from oysters. [PDF]

open access: yesPLoS One
Aldaroub J   +5 more
europepmc   +1 more source

Transcriptional Adaptations to Muscle Loading in a Murine Model of Achilles Tendinopathy. [PDF]

open access: yesJ Orthop Res
Easley DC   +5 more
europepmc   +1 more source

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