Results 81 to 90 of about 1,978,611 (289)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Packers [PDF]

open access: yes, 2018
An army officer reminisces about her past love, her military career, and a great pair of cowboy boots. Articles, stories, and other compositions in this archive were written by participants in the Mighty Pen Project.
Liechti, Beth
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

A taxonomic review of species of the Neotropical pericaline genus Oreodicastes Maindron, 1905 (Coleoptera: Carabidae: Lebiini) [PDF]

open access: yes, 2001
Based on adult character states, a key is provided to the seven known species of Oreodicastes Maindron 1905 (type species Oxyglossus subcyaneus Chaudoir 1843). Two new species (with type locality) are described: O. virginia (Fa zenda dos Campos, Virginia,
Ball, George E., Shpeley, Danny
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Centenario del nacimiento de Virginia Apgar (1909 2009)

open access: yesRevista Cubana de Anestesiología y Reanimación, 2011
Introducción. El motivo de este artículo es la celebración de los 60 años de la Sociedad Cubana de Anestesiología y Reanimación, fundada en septiembre de 1950 con el nombre de Sociedad Nacional de Anestesiología. Objetivo.
Carlos Antonio Vilaplana Santaló
doaj   +2 more sources

Saturday Extra: Guerilla Civic Engagement on the Landscape [PDF]

open access: yes, 2011
Over at Civil War Memory, Kevin Levin brought the community\u27s attention to some installations placed on the fences surrounding a few of the statues along Monument Avenue in Richmond, Virginia.
Rudy, John M.
core   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

open access: yesFEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner   +6 more
wiley   +1 more source

Virginia Arcadia: The Natural Bridge in American Art

open access: yesPanorama, 2022
Debra Hanson
doaj   +1 more source

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