Results 71 to 80 of about 111,761 (236)

Biochemical analyses of HIV-1 virion RNAs.

open access: yes, 2013
(A) Representative denaturing Northern analyses of virion RNAs. The four lanes shown are generated from the same gel and rearranged for clarity. (B) Representative analyses of velocity sedimentation of virion RNAs. The copy numbers of XLong and 28S rRNAs
Vinay K. Pathak (265960)   +9 more
core   +1 more source

Single and dual RPA‐CRISPR/Cas assays for point‐of‐need detection of Stewart's wilt pathogen (Pantoea stewartii subsp. stewartii) of corn and Maize dwarf mosaic virus

open access: yesPest Management Science, Volume 81, Issue 4, Page 1988-1999, April 2025.
Schematic diagram of the single and dual RPA‐CRISPR/Cas12a/13a diagnostic assays for the detection of Pantoea stewartii subsp. stewartii and Maize dwarf mosaic virus. The validated assays provide a useful and sensitive molecular tool for detecting two quarantine pathogens of maize within a minimal resource framework suitable for fast‐tracking the ...
Qian Tian   +6 more
wiley   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux   +6 more
wiley   +1 more source

Proteomic analysis of pathogenic and attenuated alcelaphine herpesvirus 1

open access: yes, 2008
The gammaherpesvirus alcelaphine herpesvirus 1 (AlHV-1) causes malignant catarrhal fever in susceptible ungulates but infects its natural host, wildebeest, without obvious clinical signs.
Stewart, James P.   +5 more
core  

Identification of stable clones from virion pools.

open access: yes, 2013
(A–D) Stable Env cDNAs were rescued using RT-PCR on pooled viral RNA. Variant Env clones derived from the heat-selected B2 (A; HB2) and C11 (B; HC11) virion pools, the GuHCl-selected B2 pools (C; GB2), and the 37°C-selected M1 pool (D; PM1) were tested ...
Michael B. Zwick (105335)   +1 more
core   +1 more source

Modular Molecular Design and Self‐Assembled Nanostructures of Saccharide‑Appended Cyclic Dipeptides for Glycosidase‑Responsive Supramolecular Hydrogels

open access: yesSmall, EarlyView.
Saccharide‐appended cyclic dipeptides are designed and developed as building blocks for glycosidase‐responsive supramolecular hydrogels. Their aqueous self‐assembly enables β‐galactosidase‐triggered gel‐to‐sol and neuraminidase‐triggered sol‐to‐gel transition systems, highlighting their potential as glycosidase‐responsive soft materials for biomedical ...
Shintaro Sugiura   +6 more
wiley   +1 more source

Identification of Adomavirus Virion Proteins

open access: yes, 2018
Adenoviruses, papillomaviruses, and polyomaviruses are collectively known as small DNA tumor viruses. Although it has long been recognized that small DNA tumor virus oncoproteins and capsid proteins show a variety of structural and functional ...
Qiong Shi   +17 more
core   +1 more source

Maltase 1 regulates DENV2 infection and life history in Aedes aegypti

open access: yesInsect Science, EarlyView.
Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li   +5 more
wiley   +1 more source

Genome segment S8 of grass carp hemorrhage virus encodes a virion protein

open access: yes, 2001
The complete nucleotide sequence of the genome segment S8 of grass carp hemorrhage virus (GCHV) was determined from cDNA corresponding to the viral genomic RNA. It is 1,287 nucleotides in length and contains a large open reading frame that could encode a
Zhu, ZY   +4 more
core  

Virion gH/gL binds to GAGs.

open access: yes, 2013
A. Wild-type (gL+) and gL-deficient (gL−) virions were lysed in 1% digitonin, then immunoprecipitated with either heparin-agarose or protein A-sepharose plus mAb 7E5 (gH/gL-specific) or 8C1 (which recognizes all forms of gH).
Susanna Colaco (41652)   +2 more
core   +1 more source

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