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Molecular Characterization of Measles and Rubella Virus Strains from the 2018–2019 Epidemic in Madagascar [PDF]

open access: yesPathogens
Madagascar experienced a severe measles epidemic between September 2018 and mid-2019, resulting in more than 146,000 cases and 1200 deaths, primarily among children under 15 years of age.
Richter Razafindratsimandresy   +9 more
doaj   +2 more sources

Evaluation and comparison of three qPCR commercial assays and three automated platforms for the detection of monkeypox virus DNA [PDF]

open access: yesMicrobiology Spectrum
This study compared the analytical performance of three commercial real-time PCR assays for the detection of monkeypox virus (MPV) DNA, on their own platforms and/or on open platforms, were evaluated at the virology laboratory of Grenoble-Alpes ...
Marie Usal   +8 more
doaj   +2 more sources

IQGAP1 and IQGAP3 are critical host factors for Marburg virus replication, nucleocapsid transport, and cell-to-cell spread [PDF]

open access: yesCellular and Molecular Life Sciences
The IQGAP protein family—comprising IQGAP1, IQGAP2, and IQGAP3—exhibits structural similarity but fulfils distinct cellular functions. We previously demonstrated that IQGAP1 is recruited to Marburg virus (MARV)-induced inclusion bodies (IBs) and ...
Olga Dolnik   +8 more
doaj   +2 more sources

Benefits of HIV‐1 transmission cluster surveillance: a French retrospective observational study of the molecular and epidemiological co‐evolution of recent circulating recombinant forms 94 and 132 [PDF]

open access: yesJournal of the International AIDS Society
Introduction Molecular surveillance is an important tool for detecting chains of transmission and controlling the HIV epidemic. This can also improve our knowledge of molecular and epidemiological factors for the optimization of prevention. Our objective
Marc Wirden   +17 more
doaj   +2 more sources

Anti-Coxsackievirus B4 Activity of Serum and Saliva from Mice Exposed to the Virus via the Mucosal Route [PDF]

open access: yesMicroorganisms
Coxsackieviruses B are single-stranded RNA viruses belonging to the Enterovirus genus and are associated with various clinical outcomes, ranging from acute infections to chronic diseases, such as type 1 diabetes (T1D).
Chaldam Jespère Mbani   +8 more
doaj   +2 more sources

Role of innate immune and inflammatory signaling in West Nile virus tropism and neuronal and glial cell death [PDF]

open access: yesScientific Reports
West Nile virus (WNV) is a mosquito-borne virus that causes severe neurological disease in humans. Despite substantial advances, our knowledge of the mechanisms involved in damaging the human brain is still limited.
Valentine Chaillot   +6 more
doaj   +2 more sources

Correction: Human neuroblastoma cells with acquired resistance to the p53 activator RITA retain functional p53 and sensitivity to other p53 activating agents [PDF]

open access: yesCell Death and Disease
M. Michaelis   +11 more
doaj   +2 more sources

Sciences et société au prisme de la pandémie de Covid-19 : la recherche sur les origines naturelles du SARS-CoV-2☆

open access: yesNatures Sciences Sociétés, 2022
La « crise de la Covid-19 » a constitué un moment important de débats – sur la marche de la science et les conditions de travail des scientifiques – dont on peut déjà tirer quelques leçons de sociologie des sciences.
Jouvenet Morgan
doaj   +1 more source

Les enjeux de la mise en œuvre des activités conjointes tuberculose et VIH dans les districts sanitaires de Bamako (Mali).

open access: yesRevue Malienne d’Infectiologie et de Microbiologie, 2018
Introduction : Au Mali, le rapport du programme national de lutte contre la tuberculose (PNLT) révèle en 2015 que 541/4035 soit 13% des cas de tuberculose toutes formes dépistées sont infectées par le VIH.
Samaké H   +6 more
doaj   +3 more sources

Comparison of Rapid and Automated Antigen Detection Tests for the Diagnosis of SARS-CoV-2 Infection

open access: yesDiagnostics, 2022
SARS-CoV-2 viral antigen detection may be an interesting alternative to RT-PCR for the diagnosis of SARS-CoV-2 infection as a less laborious or expensive method but requires validation.
Dorian Petonnet   +8 more
doaj   +1 more source

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