IQGAP1 and IQGAP3 are critical host factors for Marburg virus replication, nucleocapsid transport, and cell-to-cell spread [PDF]
The IQGAP protein family—comprising IQGAP1, IQGAP2, and IQGAP3—exhibits structural similarity but fulfils distinct cellular functions. We previously demonstrated that IQGAP1 is recruited to Marburg virus (MARV)-induced inclusion bodies (IBs) and ...
Olga Dolnik +8 more
doaj +2 more sources
Role of innate immune and inflammatory signaling in West Nile virus tropism and neuronal and glial cell death [PDF]
West Nile virus (WNV) is a mosquito-borne virus that causes severe neurological disease in humans. Despite substantial advances, our knowledge of the mechanisms involved in damaging the human brain is still limited.
Valentine Chaillot +6 more
doaj +2 more sources
Benefits of HIV‐1 transmission cluster surveillance: a French retrospective observational study of the molecular and epidemiological co‐evolution of recent circulating recombinant forms 94 and 132 [PDF]
Introduction Molecular surveillance is an important tool for detecting chains of transmission and controlling the HIV epidemic. This can also improve our knowledge of molecular and epidemiological factors for the optimization of prevention. Our objective
Marc Wirden +17 more
doaj +2 more sources
Anti-Coxsackievirus B4 Activity of Serum and Saliva from Mice Exposed to the Virus via the Mucosal Route [PDF]
Coxsackieviruses B are single-stranded RNA viruses belonging to the Enterovirus genus and are associated with various clinical outcomes, ranging from acute infections to chronic diseases, such as type 1 diabetes (T1D).
Chaldam Jespère Mbani +8 more
doaj +2 more sources
La « crise de la Covid-19 » a constitué un moment important de débats – sur la marche de la science et les conditions de travail des scientifiques – dont on peut déjà tirer quelques leçons de sociologie des sciences.
Jouvenet Morgan
doaj +1 more source
Comparison of Rapid and Automated Antigen Detection Tests for the Diagnosis of SARS-CoV-2 Infection
SARS-CoV-2 viral antigen detection may be an interesting alternative to RT-PCR for the diagnosis of SARS-CoV-2 infection as a less laborious or expensive method but requires validation.
Dorian Petonnet +8 more
doaj +1 more source
Introduction : Au Mali, le rapport du programme national de lutte contre la tuberculose (PNLT) révèle en 2015 que 541/4035 soit 13% des cas de tuberculose toutes formes dépistées sont infectées par le VIH.
Samaké H +6 more
doaj +3 more sources
Traitement d’un lymphome agressif chez un babouin naturellement infecté par STLV-1
L’infection par le virus T Lymphotrope Humain de Type 1 (HTLV-1) est associée à une lymphoprolifération maligne nommée Leucémie/Lymphome T de l’adulte (ATLL).
Jocelyn Turpin +9 more
doaj +1 more source
BK Polyomavirus Micro-RNAs: Time Course and Clinical Relevance in Kidney Transplant Recipients
Background: Kidney transplant recipients (KTRs) are exposed to a high risk of BK polyomavirus (BKPyV) replication, which in turn may lead to graft loss.
Baptiste Demey +7 more
doaj +1 more source
The respiratory syncytial virus nucleoprotein–RNA complex forms a left-handed helical nucleocapsid [PDF]
Respiratory Syncytial Virus (RSV) is an important human pathogen. Its nucleocapsid (NC), which comprises the negative sense RNA viral genome coated by the viral nucleoprotein N, is a critical assembly that serves as template for both mRNA synthesis and ...
Bhella +10 more
core +3 more sources

