Results 21 to 30 of about 32,354 (216)

Covalently linked dengue virus envelope glycoprotein dimers reduce exposure of the immunodominant fusion loop epitope

Nature Communications, 2017
The immunodominant epitope of dengue virus envelope protein (E) induces poorly neutralizing antibodies, which poses a problem for vaccine development. Here, the authors engineer covalently locked E dimers exposing an epitope that has been shown to induce
Alexander Rouvinski, Wanwisa Dejnirattisai, Pablo Guardado-Calvo, Marie-Christine Vaney, Arvind Sharma, Stéphane Duquerroy, Piyada Supasa, Wiyada Wongwiwat, Ahmed Haouz, Giovanna Barba-Spaeth, Juthathip Mongkolsapaya, Félix A. Rey, Gavin R. Screaton   +12 more
doaj   +1 more source

Quantification of Lyssavirus-Neutralizing Antibodies Using Vesicular Stomatitis Virus Pseudotype Particles

Viruses, 2016
Rabies is a highly fatal zoonotic disease which is primarily caused by rabies virus (RABV) although other members of the genus Lyssavirus can cause rabies as well. As yet, 14 serologically and genetically diverse lyssaviruses have been identified, mostly
Sarah Moeschler, Samira Locher, Karl-Klaus Conzelmann, Beate Krämer, Gert Zimmer   +4 more
doaj   +1 more source

Development of an artificial synovial fluid useful for studying Staphylococcus epidermidis joint infections

Frontiers in Cellular and Infection Microbiology, 2022
Staphylococcus epidermidis is a major causative agent of prosthetic joint infections (PJI). The ability to form biofilms supports this highly selective pathogenic potential. In vitro studies essentially relying on phenotypic assays and genetic approaches
Johanna Stamm, Samira Weißelberg, Anna Both, Antonio Virgilio Failla, Gerhard Nordholt, Henning Büttner, Stefan Linder, Martin Aepfelbacher, Holger Rohde, Holger Rohde   +9 more
doaj   +1 more source

Was könnten Virologen künftig besser machen?

Monitor Versorgungsforschung
Um es gleich am Anfang zu sagen: Virologie und Seuchenbekämpfung sind wie Klingel und Fahrradfahren: Ersteres ist jeweils notwendig, dafür aber nicht ausreichend.
Prof. Dr. Klaus Stöhr
doaj   +1 more source

Implementation of the FilmArray ME panel in laboratory routine using a simple sample selection strategy for diagnosis of meningitis and encephalitis

BMC Infectious Diseases, 2020
Background Infectious meningitis is a serious disease and patient outcome relies on fast and reliable diagnostics. A syndromic panel testing approach like the FilmArray ME can accelerate diagnosis and therefore decrease the time to pathogen specific ...
Susanne Pfefferle, Martin Christner, Martin Aepfelbacher, Marc Lütgehetmann, Holger Rohde   +4 more
doaj   +1 more source

Measles and Rubella Incidence and Molecular Epidemiology in Senegal: Temporal and Regional Trends during Twelve Years of National Surveillance, 2010–2021

Viruses, 2022
We investigated the epidemiology of measles and rubella infections in Senegal based on data from twelve consecutive years of laboratory-based surveillance (2010–2021) and conducted phylogenetic analyses of circulating measles viruses.
Mamadou Malado Jallow, Bacary Djilocalisse Sadio, Marie Pedapa Mendy, Sara Sy, Amary Fall, Davy Kiori, Ndiendé Koba Ndiaye, Yague Diaw, Déborah Goudiaby, Boly Diop, Mbayame Ndiaye Niang, Elizabeth J. A. Fitchett, Ndongo Dia   +12 more
doaj   +1 more source

Une année dans Virologie : des virus persistent, d’autres émergent

, 2022
International audienceL’année 2022 est toujours marquée par la poursuite de la pandémie de Covid-19 mais cela ne doit pas nous faire oublier que d’autres virus restent préoccupants par leur chronicité, par leur émergence ou par leur endémicité dans le ...
Vitour, Damien, Gilmer, David, Saulnier, Aure, Nisole, Sébastien, Gatignol, Anne, Tordo, Noël, Lévêque, Nicolas   +6 more
core   +1 more source

Serine-Arginine Protein Kinase 1 Regulates Ebola Virus Transcription

mBio, 2020
Ebola virus (EBOV) causes a severe and often fatal disease for which no approved vaccines or antivirals are currently available. EBOV VP30 has been described as a viral phosphoprotein, and nonphosphorylated VP30 is essential and sufficient to support ...
Yuki Takamatsu, Verena Krähling, Larissa Kolesnikova, Sandro Halwe, Clemens Lier, Stefan Baumeister, Takeshi Noda, Nadine Biedenkopf, Stephan Becker   +8 more
doaj   +1 more source

Une histoire de la virologie

, 2022
La virologie est née à la fin du XIXe siècle de la reconnaissance d’agents infectieux, dits filtrables, qui franchissaient les filtres destinés à retenir les bactéries.
Henri Agut
core   +1 more source

L’épizootie de Peste Porcine Africaine : virologie, épidémiologie et perspectives de contrôle

INRAE Productions Animales, 2020
La Peste Porcine Africaine (PPA) est une maladie infectieuse émergente des suidés domestiques et sauvages. Cette maladie contagieuse entre suidés, non transmissible à l’Homme, est à l’origine d’un syndrome hémorragique souvent fatal chez les porcs ...
Nicolas ROSE, Marie-Frédérique LE POTIER   +1 more
doaj   +1 more source