Results 61 to 70 of about 23,669 (217)

Evolution of Epstein–Barr Virus Infection Seroprevalence in a French University Hospital over 11 Years, Including the COVID-19 Pandemic, 2013–2023

Microorganisms
Epstein–Barr virus (EBV) is one of the most prevalent human viruses worldwide. The COVID-19 pandemic, with its social distancing measures, has disrupted the circulation of many viruses.
Aurélien Aubry, Catherine Francois, Baptiste Demey, Marie Louchet-Ducoroy, Christine Pannier, Christine Segard, Etienne Brochot, Sandrine Castelain   +7 more
doaj   +1 more source

Marburg virus regulates the IRE1/XBP1-dependent unfolded protein response to ensure efficient viral replication

Emerging Microbes and Infections, 2019
Viruses regulate cellular signalling pathways to ensure optimal viral replication. During Marburg virus (MARV) infection, large quantities of the viral glycoprotein GP are produced in the ER; this may result in the activation of the unfolded protein ...
Cornelius Rohde, Stephan Becker, Verena Krähling   +2 more
doaj   +1 more source

Detection of Multiple Microorganisms in Ruminant Ticks in Senegal Using High‐Throughput Microfluidic Real‐Time PCR

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Ticks are major vectors of numerous pathogens affecting both livestock and humans. In Senegal, data on the diversity of tick‐borne pathogens (TBPs) in ruminant‐associated ticks remain limited. In total, 1703 ticks were collected from goats, sheep, and cattle across three ecological zones of Senegal (Sudanian, Sahelian, and Sudano‐Sahelian).
Aliou Khoule, Clemence Galon, Déthié Ngom, Baye Bado Ndoye, Ousseynou Sene, Ibrahima Dia, Gamou Fall, Mawlouth Diallo, Sara Moutailler, Diawo Diallo, Nan-hua Chen   +10 more
wiley   +1 more source

Impact of Hanks Kinase‐Dependent Phosphorylation of CodY on the Physiology and Virulence in Bacillus cereus

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
CodY is a global regulator whose phosphorylation at serine 215 by PrkC/YbdM alters its DNA binding, thereby modulating gene expression and impacting motility, biofilm formation, cytotoxicity, and pathogenicity in Bacillus cereus, suggesting a conserved regulatory mechanism in Firmicutes ABSTRACT CodY acts as a key regulatory protein involved in ...
Mounia Kortebi, Céline Henry, Christophe Buisson, Christelle Lemy, Michel Gohar, Didier Lereclus, Ivan Mijakovic, Sandrine Poncet   +7 more
wiley   +1 more source

An intranasal live-attenuated SARS-CoV-2 vaccine limits virus transmission

Nature Communications
The development of effective SARS-CoV-2 vaccines has been essential to control COVID-19, but significant challenges remain. One problem is intramuscular administration, which does not induce robust mucosal immune responses in the upper airways—the ...
Julia M. Adler, Ricardo Martin Vidal, Christine Langner, Daria Vladimirova, Azza Abdelgawad, Daniela Kunecova, Xiaoyuan Lin, Geraldine Nouailles, Anne Voss, Sandra Kunder, Achim D. Gruber, Haibo Wu, Nikolaus Osterrieder, Dusan Kunec, Jakob Trimpert   +14 more
doaj   +1 more source

Human Papillomavirus Viral Load as Triage Biomarker for High‐Grade Cervical Lesions and Invasive Cervical Carcinoma: A Cross‐Sectional Study

Health Science Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background and Aims We herein evaluated whether intra‐tissue HPV viral load may constitute a triage biomarker to differentiate between high‐grade precancerous cervical lesions from intra cervical cancer (ICC). Methods 50 biopsy samples prospectively obtained from women living in Mauritania suffering from high‐grade cervical intraepithelial ...
Mariem Salma Abdoudaim, Laurent Bélec, Mohamed Lemine Cheikh Brahim Ahmed, Nacer Dine Mohamed Baba, Ralph‐Sydney Mboumba Bouassa, Mohamed Vall Mohamed Abdellahi   +5 more
wiley   +1 more source

Valganciclovir Underdosing Is Associated With Cytomegalovirus DNAemia During Universal Prophylaxis: A Real‐Life Case Control Retrospective Study

Journal of Medical Virology, Volume 97, Issue 11, November 2025.
ABSTRACT Universal prophylaxis or a preemptive strategy with valganciclovir (VGCV) is recommended for prevention of cytomegalovirus (CMV) infections after kidney transplantation. We combined both strategies during the first 3 months post‐transplantation.
Pierre‐Antonin Rigon, Justine Solignac, Christine Zandotti, Marion Gully, Philippe Brunet, Noémie Resseguier, Tristan Legris, Valérie Moal   +7 more
wiley   +1 more source

Assessing scoring metrics for AlphaFold2 and AlphaFold3 protein complex predictions

Protein Science, Volume 34, Issue 11, November 2025.
Abstract Recent breakthroughs in AI‐driven protein structure prediction have revolutionized structural biology, unlocking new possibilities to model complex biomolecular interactions. We evaluated widely used scoring metrics for assessing models predicted by ColabFold with templates, ColabFold without templates, and AlphaFold3.
Luca R. Genz, Sanjana Nair, Natan Nagar, Maya Topf   +3 more
wiley   +1 more source

Antibacterial activity of the stem bark of Tieghemella Heckelii Pierre ex. A Chev against methicillin-resistant Staphylococcus aureus

BMC Complementary and Alternative Medicine, 2017
Background Tieghemella heckelii (Sapotaceae) is a medicinal plant used in Africa, particularly in Côte d’Ivoire for treating various diseases including infections.
B. G. Kipre, N.K. Guessennd, M.W. Koné, V. Gbonon, J. K. Coulibaly, M. Dosso   +5 more
doaj   +1 more source

À propos de la virologie informatique

, 2010
National audienceQu’est-ce qu’un virus ? Comment se fait une attaque virale ? En quoi consiste la recherche en virologie informatique ?
Marion, Jean-Yves, Jongwane, Joanna
core   +1 more source