Results 61 to 70 of about 32,354 (216)

Marburg virus regulates the IRE1/XBP1-dependent unfolded protein response to ensure efficient viral replication

open access: yesEmerging Microbes and Infections, 2019
Viruses regulate cellular signalling pathways to ensure optimal viral replication. During Marburg virus (MARV) infection, large quantities of the viral glycoprotein GP are produced in the ER; this may result in the activation of the unfolded protein ...
Cornelius Rohde   +2 more
doaj   +1 more source

Murine cytomegalovirus genomic material in marrow cells; relation to altered leukocyte counts during sublethal infection of mice [PDF]

open access: yes, 1987
To investigate infection of hematopoietic cells by murine cytomegalovirus (MCMV), we used in situ hybridization to detect MCMV genomic material in marrow cells during sublethal infection of three-week-old mice.
Perlman, S.   +4 more
core   +2 more sources

Detection of Multiple Microorganisms in Ruminant Ticks in Senegal Using High‐Throughput Microfluidic Real‐Time PCR

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Ticks are major vectors of numerous pathogens affecting both livestock and humans. In Senegal, data on the diversity of tick‐borne pathogens (TBPs) in ruminant‐associated ticks remain limited. In total, 1703 ticks were collected from goats, sheep, and cattle across three ecological zones of Senegal (Sudanian, Sahelian, and Sudano‐Sahelian).
Aliou Khoule   +10 more
wiley   +1 more source

An intranasal live-attenuated SARS-CoV-2 vaccine limits virus transmission

open access: yesNature Communications
The development of effective SARS-CoV-2 vaccines has been essential to control COVID-19, but significant challenges remain. One problem is intramuscular administration, which does not induce robust mucosal immune responses in the upper airways—the ...
Julia M. Adler   +14 more
doaj   +1 more source

Impact of Hanks Kinase‐Dependent Phosphorylation of CodY on the Physiology and Virulence in Bacillus cereus

open access: yesMicrobiologyOpen, Volume 14, Issue 6, December 2025.
CodY is a global regulator whose phosphorylation at serine 215 by PrkC/YbdM alters its DNA binding, thereby modulating gene expression and impacting motility, biofilm formation, cytotoxicity, and pathogenicity in Bacillus cereus, suggesting a conserved regulatory mechanism in Firmicutes ABSTRACT CodY acts as a key regulatory protein involved in ...
Mounia Kortebi   +7 more
wiley   +1 more source

Human Papillomavirus Viral Load as Triage Biomarker for High‐Grade Cervical Lesions and Invasive Cervical Carcinoma: A Cross‐Sectional Study

open access: yesHealth Science Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background and Aims We herein evaluated whether intra‐tissue HPV viral load may constitute a triage biomarker to differentiate between high‐grade precancerous cervical lesions from intra cervical cancer (ICC). Methods 50 biopsy samples prospectively obtained from women living in Mauritania suffering from high‐grade cervical intraepithelial ...
Mariem Salma Abdoudaim   +5 more
wiley   +1 more source

Valganciclovir Underdosing Is Associated With Cytomegalovirus DNAemia During Universal Prophylaxis: A Real‐Life Case Control Retrospective Study

open access: yesJournal of Medical Virology, Volume 97, Issue 11, November 2025.
ABSTRACT Universal prophylaxis or a preemptive strategy with valganciclovir (VGCV) is recommended for prevention of cytomegalovirus (CMV) infections after kidney transplantation. We combined both strategies during the first 3 months post‐transplantation.
Pierre‐Antonin Rigon   +7 more
wiley   +1 more source

Antibacterial activity of the stem bark of Tieghemella Heckelii Pierre ex. A Chev against methicillin-resistant Staphylococcus aureus

open access: yesBMC Complementary and Alternative Medicine, 2017
Background Tieghemella heckelii (Sapotaceae) is a medicinal plant used in Africa, particularly in Côte d’Ivoire for treating various diseases including infections.
B. G. Kipre   +5 more
doaj   +1 more source

À propos de la virologie informatique

open access: yes, 2010
National audienceQu’est-ce qu’un virus ? Comment se fait une attaque virale ? En quoi consiste la recherche en virologie informatique ?
Marion, Jean-Yves, Jongwane, Joanna
core   +1 more source

Exposure to pairs of Aeromonas strains enhances virulence in the Caenorhabditis elegans infection model

open access: yesFrontiers in Microbiology, 2015
Aeromonad virulence remains poorly understood, and is difficult to predict from strain characteristics. In addition, infections are often polymicrobial (i.e., are mixed infections), and 5-10% of such infections include two distinct aeromonads, which has ...
Thomas eMosser   +10 more
doaj   +1 more source

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