Results 71 to 80 of about 23,485 (218)
CodY is a global regulator whose phosphorylation at serine 215 by PrkC/YbdM alters its DNA binding, thereby modulating gene expression and impacting motility, biofilm formation, cytotoxicity, and pathogenicity in Bacillus cereus, suggesting a conserved regulatory mechanism in Firmicutes ABSTRACT CodY acts as a key regulatory protein involved in ...
Mounia Kortebi +7 more
wiley +1 more source
Risk assessment of spreading Banana streak viruses in the Dominican Republic through large scale cultivation of plantain cultivars and hybrids harbouring infectious eBSVs. [O.33] [PDF]
Most cultivated plantains are interspecific cultivars or hybrids: they harbour Musa acuminata (A) genomes and Musa balbisiana (B) genomes which hosts infectious endogenous Banana streak virus sequences (eBSVs).
Acina Manbole, Isabelle Nina +5 more
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ABSTRACT Background and Aims We herein evaluated whether intra‐tissue HPV viral load may constitute a triage biomarker to differentiate between high‐grade precancerous cervical lesions from intra cervical cancer (ICC). Methods 50 biopsy samples prospectively obtained from women living in Mauritania suffering from high‐grade cervical intraepithelial ...
Mariem Salma Abdoudaim +5 more
wiley +1 more source
An intranasal live-attenuated SARS-CoV-2 vaccine limits virus transmission
The development of effective SARS-CoV-2 vaccines has been essential to control COVID-19, but significant challenges remain. One problem is intramuscular administration, which does not induce robust mucosal immune responses in the upper airways—the ...
Julia M. Adler +14 more
doaj +1 more source
Rede, in verkorte vorm uitgesproken ter gelegenheid van het aanvaarden van het ambt van bijzonder hoogleraar in de virologie aan het Erasmus faculteit van de Erasmus Universiteit Rotterdam op 8 maart ...
Koopmans D.V.M., M.P.G. (Marion)
core
ABSTRACT Universal prophylaxis or a preemptive strategy with valganciclovir (VGCV) is recommended for prevention of cytomegalovirus (CMV) infections after kidney transplantation. We combined both strategies during the first 3 months post‐transplantation.
Pierre‐Antonin Rigon +7 more
wiley +1 more source
Endogenous banana streak virus sequences (eBSV) are likely transcriptionally silenced in the resistant seedy diploid Musa balbisiana Pisang Klutuk Wulung (PKW). [P.50] [PDF]
The B genome of banana (Musa sp.) harbours integrations of Banana streak virus (eBSV) for at least three BSV species, whereas this badnavirus does not require integration for the replication of its ds DNA genome.
Caruana, Marie-Line +6 more
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Assessing scoring metrics for AlphaFold2 and AlphaFold3 protein complex predictions
Abstract Recent breakthroughs in AI‐driven protein structure prediction have revolutionized structural biology, unlocking new possibilities to model complex biomolecular interactions. We evaluated widely used scoring metrics for assessing models predicted by ColabFold with templates, ColabFold without templates, and AlphaFold3.
Luca R. Genz +3 more
wiley +1 more source
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. [PDF]
Hepatitis C virus (HCV) infection is closely tied to the lipid metabolism of liver cells. Here we identify the triglyceride-synthesizing enzyme diacylglycerol acyltransferase-1 (DGAT1) as a key host factor for HCV infection.
Carpentier, Arnaud +7 more
core +1 more source
ABSTRACT Influenza, respiratory syncytial virus (RSV) and SARS‐CoV‐2 are among the main respiratory viruses circulating in the population, with a significant burden on public health. While individuals at higher risk are more likely to develop severe symptoms leading to hospitalization, viral circulation in the community remains less extensively ...
Cécile Chauvel +18 more
wiley +1 more source

