Results 21 to 30 of about 269,194 (170)
SARS-CoV-2 (COVID-19) by the numbers
eLife, 2020 The COVID-19 pandemic is a harsh reminder of the fact that, whether in a single human host or a wave of infection across continents, viral dynamics is often a story about the numbers.
Yinon M Bar-On +3 more
doaj +1 more source
Verbum et Ecclesia, 2021 The coronavirus disease 2019 (COVID-19) moment has stimulated multiple intellectual attempts to make sense of the pandemic. The complexity of the challenge obviously requires an interdisciplinary approach.
Rian Venter
doaj +1 more source
Dynamics of icosahedral viruses: what does Viral Tiling Theory teach us? [PDF]
Computational and Mathematical Methods in Medicine, 9(03-04),
2008, 211 - 220., 2008 We present a top-down approach to the study of the dynamics of icosahedral virus capsids, in which each protein is approximated by a point mass. Although this represents a rather crude coarse-graining, we argue that it highlights several generic features of vibrational spectra which have been overlooked so far.
arxiv +1 more source
Application of Machine Learning in understanding plant virus pathogenesis: Trends and perspectives on emergence, diagnosis, host-virus interplay and management [PDF]
arXiv, 2021 Inclusion of high throughput technologies in the field of biology has generated massive amounts of biological data in the recent years. Now, transforming these huge volumes of data into knowledge is the primary challenge in computational biology. The traditional methods of data analysis have failed to carry out the task.
arxiv
Evolution of Virology: Science History through Milestones and Technological Advancements
VirusesThe history of virology, which is marked by transformative breakthroughs, spans microbiology, biochemistry, genetics, and molecular biology. From the development of Jenner’s smallpox vaccine in 1796 to 20th-century innovations such as ultrafiltration and
Kunlan Zuo +9 more
doaj +1 more source
mSphere, 2018 Heteroaryldihydropyrimidines (HAPs) are compounds that inhibit hepatitis B virus (HBV) replication by modulating viral capsid assembly. While their biophysical effects on capsid assembly in vitro have been previously studied, the effect of HAP treatment ...
Andrew D. Huber +14 more
doaj +1 more source
At the crossroads of epidemiology and biology: bridging the gap between SARS-CoV-2 viral strain properties and epidemic wave characteristics [PDF]
arXiv, 2023 The COVID-19 pandemic has given rise to numerous articles from different scientific fields (epidemiology, virology, immunology, airflow physics...) without any effort to link these different insights. In this review, we aim to establish relationships between epidemiological data and the characteristics of the virus strain responsible for the epidemic ...
arxiv
Viral Evasion of the Complement System and Its Importance for Vaccines and Therapeutics
Frontiers in Immunology, 2020 The complement system is a key component of innate immunity which readily responds to invading microorganisms. Activation of the complement system typically occurs via three main pathways and can induce various antimicrobial effects, including ...
Jack Mellors +4 more
doaj +1 more source
NK-B cell cross talk induces CXCR5 expression on natural killer cells
iScience, 2021 Summary: B cell follicles (BCFs) in lymph nodes (LNs) are generally exempt of CD8+ T and NK cells. African green monkeys (AGMs), a natural host of simian immunodeficiency virus (SIV), display NK cell-mediated viral control in BCF.
Philippe Rascle +10 more
doaj
iScience, 2021 Summary: Broadly neutralizing antibodies (bnAbs) against HIV-1 are frequently associated with the presence of autoreactivity/polyreactivity, a property that can limit their use as therapeutic agents.
Edurne Rujas +16 more
doaj