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Comparison of gut virome in Kenyan infants born to women with and without HIV [PDF]
iScienceSummary: The gut virome develops in infancy, seeded from numerous sources including the maternal virome. Altered infant virome development from exposure to maternal HIV infection could contribute to the higher observed morbidity among children who are ...
Emily R. Begnel +13 more
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The Human Virome in Health and Its Remodeling During HIV Infection and Antiretroviral Therapy: A Narrative Review [PDF]
MicroorganismsThe human virome represents a fundamental yet understudied component of the microbiome, influencing immune regulation and disease. Given the profound immune dysregulation and microbial imbalance associated with HIV infection, understanding virome ...
Federico Cesanelli +7 more
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The Human Respiratory Virome in Health and Disease: Interactions, Dysbiosis, and Methodological Challenges [PDF]
Advanced GeneticsThe human respiratory virome is an underexplored component of the microbiome that includes diverse DNA and RNA viruses such as eukaryotic viruses, bacteriophages, and archaeal viruses.
Xiaoxuan Yao, Xiaohui Zou, Bin Cao
doaj +2 more sources
The emerging role of the gut virome in necrotizing enterocolitis
HeliyonNecrotizing enterocolitis (NEC) is the most common gastrointestinal emergency in neonates, particularly preterm infants. Many factors can lead to NEC, but microbial dysbiosis is one of the most important risk factors that can induce this disease.
Cong Yi, Jia Chen, Xiang She
doaj +2 more sources
Quantitative Temporal Viromics [PDF]
Annual Review of Virology, 2021 The abundance, localization, modifications, and protein-protein interactions of many host cell and virus proteins can change dynamically throughout the course of any viral infection. Studying these changes is critical for a comprehensive understanding of how viruses replicate and cause disease, as well as for the development of antiviral therapeutics ...
Fletcher-Etherington, Alice +1 more
openaire +2 more sources
SOVREMENNAYA PEDIATRIYA, 2019 The review is dealt with virome, a viral component of human microbiome. Modern data are discussed that concern the structure of virome, its formation during ontogenesis, the role in disease pathogeneses and in homeostasis maintenance. Special attention is payed to bacteriophages (phagobiome) as dominant members of virome.
D.S. Yankovsky +4 more
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Vaccines, 2023 Human non-polio enteroviruses (NPEVs) are the etiological agents involved in most cases of hand-foot-and-mouth disease (HFMD), herpangina and aseptic meningitis.
Tarek M. Itani +7 more
doaj +1 more source
Aquarium Viromes: Viromes of Human-Managed Aquatic Systems [PDF]
Frontiers in Microbiology, 2017 An aquarium ecosystem is home to many animal species providing conditions similar to native aquatic habitats but under highly controlled management. With a growing interest in understanding the interaction of microbiomes and resident animal health within aquarium environments, we undertook a metagenomic survey of viromes in seven aquarium systems with ...
Yiseul Kim +5 more
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The Human Virome: Viral Metagenomics, Relations with Human Diseases, and Therapeutic Applications
Viruses, 2022 The human body is colonized by a wide range of microorganisms. The field of viromics has expanded since the first reports on the detection of viruses via metagenomic sequencing in 2002. With the continued development of reference materials and databases,
Geng-Hao Bai +3 more
doaj +1 more source
Uncovering Earth’s virome [PDF]
Nature, 2016 Viruses are the most abundant biological entities on Earth, but challenges in detecting, isolating, and classifying unknown viruses have prevented exhaustive surveys of the global virome. Here we analysed over 5 Tb of metagenomic sequence data from 3,042 geographically diverse samples to assess the global distribution, phylogenetic diversity, and host ...
Paez-Espino, David +8 more
openaire +4 more sources