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The Next Generation Fecal Microbiota Transplantation: To Transplant Bacteria or Virome

open access: yesAdvanced Science, 2023
Fecal microbiota transplantation (FMT) has emerged as a promising therapeutic approach for dysbiosis‐related diseases. However, the clinical practice of crude fecal transplants presents limitations in terms of acceptability and reproductivity ...
You Yu, Weihong Wang, Faming Zhang
doaj   +2 more sources

The gut virome: A new microbiome component in health and disease

open access: yesEBioMedicine, 2022
Summary: The human gastrointestinal tract harbours an abundance of viruses, collectively known as the gut virome. The gut virome is highly heterogeneous across populations and is linked to geography, ethnicity, diet, lifestyle, and urbanisation.
Zhirui Cao   +5 more
doaj   +2 more sources

The human gut virome: composition, colonization, interactions, and impacts on human health

open access: yesFrontiers in Microbiology, 2023
The gut virome is an incredibly complex part of the gut ecosystem. Gut viruses play a role in many disease states, but it is unknown to what extent the gut virome impacts everyday human health.
Evan Pargin   +9 more
doaj   +2 more sources

A metagenomic catalog of the early-life human gut virome

open access: yesNature Communications
Early-life human gut microbiome is a pivotal driver of gut homeostasis and infant health. However, the viral component (known as “virome”) remains mostly unexplored.
Shuqin Zeng   +11 more
doaj   +2 more sources

Gut virome-wide association analysis identifies cross-population viral signatures for inflammatory bowel disease

open access: yesMicrobiome
Background The gut virome has been implicated in inflammatory bowel disease (IBD), yet a full understanding of the gut virome in IBD patients, especially across diverse geographic populations, is lacking.
Xiangge Tian   +11 more
doaj   +2 more sources

Shared and Distinct Features of Human Milk and Infant Stool Viromes. [PDF]

open access: gold, 2018
Infants acquire many of their microbes from their mothers during the birth process. The acquisition of these microbes is believed to be critical in the development of the infant immune system.
Abdul A. Saboory   +9 more
core   +7 more sources

An Exploration of the Relationship Between Gut Virome and Cardiovascular Disease: A Comprehensive Review [PDF]

open access: yesReviews in Cardiovascular Medicine
This study reviews the correlation between the gut virome and cardiovascular diseases (CVDs) and investigates the potential role of the gut virome in CVD progression.
Xiaoyu Wei   +5 more
doaj   +2 more sources

The gut ileal mucosal virome is disturbed in patients with Crohn’s disease and exacerbates intestinal inflammation in mice

open access: yesNature Communications
Gut bacteriome dysbiosis is known to be implicated in the pathogenesis of inflammatory bowel disease (IBD). Crohn’s disease (CD) is an IBD subtype with extensive mucosal inflammation, yet the mucosal virome, an empirical modulator of the bacteriome and ...
Zhirui Cao   +13 more
doaj   +2 more sources

Respiratory eukaryotic virome expansion and bacteriophage deficiency characterize childhood asthma

open access: yesScientific Reports, 2023
Asthma development and exacerbation is linked to respiratory virus infections. There is limited information regarding the presence of viruses during non-exacerbation/infection periods.
Spyridon Megremis   +12 more
doaj   +2 more sources

Role of the Virome in Vaccine-Induced Immunization [PDF]

open access: yesVaccines
The human virome—comprising viruses that can persist in a host, those that benefit the host, and those that remain latent—has gained increasing acceptance as a modulator of immune response toward vaccination.
Rossella Cianci   +6 more
doaj   +2 more sources

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