Results 41 to 50 of about 11,684 (188)
Clinical Pharmacology &Therapeutics, EarlyView.The intestinal microbiome is a key regulator of immune homeostasis, metabolism, and epithelial barrier integrity. In patients with malignant hematological diseases, particularly those undergoing hematopoietic stem cell transplantation, microbiome perturbations by reduced diversity, pathobiont expansion, and loss of beneficial metabolites are common as ...
Bálint Gergely Szabó +7 more
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Вопросы вирусологииThe aim of the review was to analyze current literature data on the mechanisms by which the influenza A virus causes a decrease in the level of the SLC7A11 (xCT) protein in human cells, which contributes to the initiation of ferroptosis.
Daria E. Korepanova, Anna E. Chernysheva
doaj +1 more source
Bile acid metabolism and signaling in human and animal health: A One Health perspective
iMetaOmics, EarlyView.Bile acids maintain host homeostasis through enterohepatic circulation, microbial transformation, and bile acid receptor signaling, thereby regulating glucose and lipid metabolism, intestinal barrier integrity, and immunity. These effects support human disease intervention and health‐oriented animal production, reducing drug dependence and residue ...
Lei Li +7 more
wiley +1 more source
VirusesHuman non-polio enteroviruses (NPEVs) cause a plethora of infections in humans, ranging from mild to severe neurological diseases including aseptic meningitis. NPEVs are the leading cause of aseptic meningitis in both children and adults worldwide.
Tarek M. Itani +4 more
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The human gut virome: composition, colonization, interactions, and impacts on human health
Frontiers in Microbiology, 2023 The gut virome is an incredibly complex part of the gut ecosystem. Gut viruses play a role in many disease states, but it is unknown to what extent the gut virome impacts everyday human health.
Evan Pargin +9 more
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Viruses in the sediments around the trenches harbor diverse survival mechanisms
iMetaOmics, EarlyView.Deep‐sea trenches are the deepest and most isolated environments in the global ocean but the diversity and adaptation of the viral communities remain poorly characterized. In this study, 5563 viral operational taxonomic units (vOTUs) were identified from sediments of the Yap Trench and Western Caroline Basin.
Yue Su +12 more
wiley +1 more source
VIROME: Downloading libraries of VIROME data v1
, 2015 This tutorial explainshow to download entire libraries of data from the VIROME web application. Wommack, K. E., J. Bhavsar, S. W. Polson, J. Chen, M. Dumas, S. Srinivasiah, M. Furman, S. Jamindar, and D. J. Nasko. 2012. VIROME: a standard operating procedure for analysis of viral metagenome sequences.
Jaysheel Bhavsar +2 more
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Эпидемиология и вакцинопрофилактикаRelevance. Prisoners have a high risk of contracting hemocontact viral infections (including HIV, viral hepatitis B and C, etc.), which creates an additional infectious burden on the entire population living in the territory. Aims.
M. V. Piterskiy +4 more
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Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention
iMetaOmics, EarlyView.The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie +12 more
wiley +1 more source
Maternal and infant gut microbiome
iMeta, EarlyView.The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang +25 more
wiley +1 more source