Results 61 to 70 of about 15,034 (222)

Probing the Viromic Frontiers [PDF]

mBio, 2015
ABSTRACT Modern molecular technology, and particularly high-throughput sequencing (HTS), has revolutionized virus discovery and expanded the depth and breadth of the virome. Recent HTS was used to identify and discover a previously undescribed member of the family Flaviviridae that has genomic features ...
openaire   +3 more sources

Multi‐omics biomarkers for intestinal infection and inflammation in inflammatory bowel disease: Current evidence, translational challenges, and diagnostic opportunities

Interdisciplinary Medicine, EarlyView.
Prospective multi‐site cohorts, multi‐omics profiling, and computational analysis may help identify biomarker patterns across clinical settings in IBD and superimposed infections. With further mechanistic and clinical validation, these signals could support the development of practical multi‐analyte tools for more precise diagnosis and management ...
Ziyu Yang, Jiayi Yao, Xinxian Zhao, Yan Xu, Yifan Chen, Tianchi Chen, Ying Jian, Min Li   +7 more
wiley   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies

Portal Hypertension &Cirrhosis, EarlyView.
This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu, Hongfan Ding, Yang Huang, Haoze Cao, Yuan Ding, Weilin Wang   +5 more
wiley   +1 more source

Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Portal Hypertension &Cirrhosis, EarlyView.
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang, Zhenyu Liu, Jun Lin, Weijing Zhang, Xianzhi Liu, Tong Zhang   +5 more
wiley   +1 more source

Iflaviruses in arthropods: when small is mighty

Insect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia, Hannah‐Isadora Huditz, Monique M. van Oers, Vera I.D. Ros   +3 more
wiley   +1 more source

Putting Rodents at the Center of One Health Programs: A Narrative Synthesis

Integrative Zoology, EarlyView.
Rodents link human, animal, and environmental health across diverse ecosystems. Rodent diversity underpins both zoonotic disease risk and ecosystem function. Environmental change reshapes rodent communities and spillover dynamics. Rodents act as reservoirs, amplifiers, and sentinels of emerging pathogens.
Steven R. Belmain
wiley   +1 more source

A Systematic Map to Identify Knowledge Gaps on a Vector of Citrus Greening Diseases: The African Citrus Triozid, Trioza erytreae (Del Guercio, 1918) (Hemiptera: Triozidae)

Journal of Applied Entomology, EarlyView.
ABSTRACT Globally, citrus production areas are threatened by greening diseases, also known as Huánglóngbíng (HLB), associated with phloem‐limited gram‐negative species of the genus Candidatus Liberibacter. Those pathogens are transmitted by either the Asian citrus psyllid, Diaphorina citri Kuwayama 1908 (Hemiptera: Psyllidae), or the African citrus ...
Kevin Malod, Evans Mauda, Aruna Manrakhan, Christopher W. Weldon   +3 more
wiley   +1 more source

Computational Viromics: Applications of the Computational Biology in Viromics Studies [PDF]

Virologica Sinica, 2021
Congyu Lu, Yousong Peng
openaire   +2 more sources

Virome in the Lungs: The Role of Anelloviruses in Childhood Respiratory Diseases

Microorganisms, 2021
More recently, increasing attention has been directed to exploring the function of the global virome in health and disease. Currently, by new molecular techniques, such as metagenomic DNA sequencing, the virome has been better unveiled.
Giulia Dodi, Marina Attanasi, Paola Di Filippo, Sabrina Di Pillo, Francesco Chiarelli   +4 more
doaj   +1 more source