Results 91 to 100 of about 26,317 (294)

Vitamin D modulation of brain-gut-virome disorder caused by polystyrene nanoplastics exposure in zebrafish (Danio rerio)

open access: yesMicrobiome, 2023
Background Many studies have investigated how nanoplastics (NPs) exposure mediates nerve and intestinal toxicity through a dysregulated brain-gut axis interaction, but there are few studies aimed at alleviating those effects. To determine whether and how
Miaomiao Teng   +7 more
semanticscholar   +1 more source

Probing the Viromic Frontiers [PDF]

open access: yesmBio, 2015
ABSTRACT Modern molecular technology, and particularly high-throughput sequencing (HTS), has revolutionized virus discovery and expanded the depth and breadth of the virome. Recent HTS was used to identify and discover a previously undescribed member of the family Flaviviridae that has genomic features ...
openaire   +4 more sources

CLAE: A High‐Fidelity Nanopore Sequencing Strategy for Read‐Level Viral Variant Detection and Environmental RNA Virus Discovery

open access: yesAdvanced Science, EarlyView.
High‐fidelity Nanopore sequencing offers a cost‐effective, portable path to uncovering viral dark matter in complex environments—but suffers from severe read‐length bias, low throughput, and limited accuracy. This study traces these limitations to core biochemical barriers and introduces CLAE, a foundational high‐fidelity platform that enables accurate,
Hannah Yu   +14 more
wiley   +1 more source

Phages and human health: More than idle hitchhikers [PDF]

open access: yes, 2019
Bacteriophages, or phages, are viruses that infect bacteria and archaea. Phages have diverse morphologies and can be coded in DNA or RNA and as single or double strands with a large range of genome sizes. With the increasing use of metagenomic sequencing
Baldridge, Megan T   +2 more
core   +2 more sources

Fecal virome transplantation is sufficient to alter fecal microbiota and drive lean and obese body phenotypes in mice

open access: yesbioRxiv, 2023
Background The gastrointestinal microbiome plays a significant role in numerous host processes and has an especially large impact on modulating the host metabolism.
Joshua M. Borin   +11 more
semanticscholar   +1 more source

B‐EPIC: A Transformer‐Based Language Model for Decoding B Cell Immunodominance Patterns

open access: yesAdvanced Science, EarlyView.
B‐Epic: Achieving high‐accuracy B cell epitope prediction through Transformer architecture. Comprehensive validation demonstrates B‐Epic's robust performance across diverse datasets. B‐Epic facilitates vaccine development for H. pylori and EBV, addressing critical public health challenges.
Jun‐Ze Liang   +16 more
wiley   +1 more source

Virome in the Lungs: The Role of Anelloviruses in Childhood Respiratory Diseases

open access: yesMicroorganisms, 2021
More recently, increasing attention has been directed to exploring the function of the global virome in health and disease. Currently, by new molecular techniques, such as metagenomic DNA sequencing, the virome has been better unveiled.
Giulia Dodi   +4 more
doaj   +1 more source

The fecal virome of domesticated animals [PDF]

open access: yesVirusDisease, 2014
Next-generation sequencing is a new research tool in our hands helping us to explore still unknown fields of human and veterinary virology. Metagenomic analysis has enabled the discovery of putative novel pathogens and the identification of the etiologic agents of several diseases, solving long-standing mysteries caused by divergent viruses.
Mihalov Kovács, Eszter   +4 more
openaire   +4 more sources

The First Virome of a Russian Vineyard

open access: yesPlants, 2023
Among other pathogens, more than 80 viruses infect grapevine. The aim of this work was to study the virome diversity of grapevine viruses and mycoviruses of a vineyard using high-throughput sequencing technologies. The grapevine virome was studied in symptomatic vines of the Rkatsiteli cultivar (V.
Svetlana Vinogradova   +5 more
openaire   +3 more sources

Unveiling Novel Viral Diversity, Biogeography, and Host Networks in Wildlife Through High‐Throughput Sequencing Data Mining

open access: yesAdvanced Science, EarlyView.
Analysis of 57 536 high‐throughput sequencing datasets uncovers a vast, hidden world of viruses in wildlife. The researchers reveal significant geographic and host‐specific patterns of viruses, and their surprising cross‐species transmissions, such as avian flu viruses infecting goats.
Hai Wang   +19 more
wiley   +1 more source

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