Results 121 to 130 of about 15,034 (222)

Role of the Virome in Vaccine-Induced Immunization

Vaccines
The human virome—comprising viruses that can persist in a host, those that benefit the host, and those that remain latent—has gained increasing acceptance as a modulator of immune response toward vaccination.
Rossella Cianci, Mario Caldarelli, Paola Brani, Annalisa Bosi, Alessandra Ponti, Cristina Giaroni, Andreina Baj   +6 more
doaj   +1 more source

Commensal Viruses Promote Intestinal Stem Cell Regeneration Following Radiation Damage by Inhibiting Hyperactivation of RIG‐I and Notch Signals

Advanced Science
Radiation‐induced intestinal injury is a common complication of abdominopelvic cancer radiotherapy, often associated with gut bacteriome dysbiosis. However, the involvement of gut virome in this process remains largely underexplored.
Xiaotong Zhao, Yu Cai, Yujia Hou, Yanjin Wu, Tingting Wei, Lili Li, Zhaojun Duan, Xinran Lu, Jiahui Meng, Haitao Zhou, Qin Wang, Jinhan Wang, Chang Xu, Liqing Du, Saijun Fan, Feng Wang, Qiang Liu, Yang Liu   +17 more
doaj   +1 more source

Gut Inflammation and Immunity: What Is the Role of the Human Gut Virome?

Mediators of Inflammation, 2015
The human virome comprises viruses that infect host cells, virus-derived elements in our chromosomes, and viruses that infect other organisms, including bacteriophages and plant viruses.
Alfredo Focà, Maria Carla Liberto, Angela Quirino, Nadia Marascio, Emilia Zicca, Grazia Pavia   +5 more
doaj   +1 more source

The gut ileal mucosal virome is disturbed in patients with Crohn’s disease and exacerbates intestinal inflammation in mice

Nature Communications
Gut bacteriome dysbiosis is known to be implicated in the pathogenesis of inflammatory bowel disease (IBD). Crohn’s disease (CD) is an IBD subtype with extensive mucosal inflammation, yet the mucosal virome, an empirical modulator of the bacteriome and ...
Zhirui Cao, Dejun Fan, Yang Sun, Ziyu Huang, Yue Li, Runping Su, Feng Zhang, Qing Li, Hongju Yang, Fen Zhang, Yinglei Miao, Ping Lan, Xiaojian Wu, Tao Zuo   +13 more
doaj   +1 more source

Longitudinal cervicovaginal bacteriome and virome alterations associate with discordant shedding and ART duration in women living with HIV in Peru

Nature Communications
Despite successful suppression of plasma HIV replication by antiretroviral therapy (ART), some women living with HIV (WLHIV) can still experience genital HIV shedding (discordant shedding).
Emily A. Kaelin, Caroline Mitchell, Jaime Soria, Alberto La Rosa, Eduardo Ticona, Robert W. Coombs, Lisa M. Frenkel, Marta E. Bull, Efrem S. Lim   +8 more
doaj   +1 more source

The colonic mucosal virome in inflammatory bowel disease reveals Crassvirales depletion and disease-specific virome features

Gut Microbes
The mucosal virome is increasingly recognized for its potential role in shaping intestinal health and disease. Building on previous findings, we analyzed the mucosal virome from 51 individuals, including newly diagnosed treatment naïve participants with ...
Austin Yan, James Butcher, David R. Mack, Alain Stintzi   +3 more
doaj   +1 more source

The emerging role of the gut virome in necrotizing enterocolitis

Heliyon
Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency in neonates, particularly preterm infants. Many factors can lead to NEC, but microbial dysbiosis is one of the most important risk factors that can induce this disease.
Cong Yi, Jia Chen, Xiang She
doaj   +1 more source

Ruminal virome

Storage of models of covariation for ruminal ...
BCEM-UniAndes
core  

Gut Virome and Inflammatory Bowel Disease

, 2016
Gut virome has been shown to yield some beneficial effects on humans, being deeply involved in physiology, inflammation, immunity, and disease. Together with transkingdom interactions, it can interplay with genetic variation in the host to establish ...
Lopetuso, Loris Riccardo, Cammarota, Giovanni, Scaldaferri, Franco, Gasbarrini, Antonio, Ianiro, Gianluca   +4 more
core   +1 more source

The Human Respiratory Virome in Health and Disease: Interactions, Dysbiosis, and Methodological Challenges

Advanced Genetics
The human respiratory virome is an underexplored component of the microbiome that includes diverse DNA and RNA viruses such as eukaryotic viruses, bacteriophages, and archaeal viruses.
Xiaoxuan Yao, Xiaohui Zou, Bin Cao
doaj   +1 more source