Results 41 to 50 of about 27,797 (299)

Sensitive detection systems for infectious agents in xenotransplantation*

Xenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Virome genomics: a tool for defining the human virome

Current Opinion in Microbiology, 2013
High throughput, deep sequencing assays are powerful tools for gaining insights into virus-host interactions. Sequencing assays can discover novel viruses and describe the genomes of novel and known viruses. Genomic information can predict viral proteins that can be characterized, describe important genes in the host that control infections, and ...
Wylie, Kristine M, Weinstock, George M, Storch, Gregory A   +2 more
openaire   +2 more sources

The Human Virome in Children and its Relationship to Febrile Illness [PDF]

, 2010
This study investigates the relationship of viruses to febrile illness in children. Subjects are normal children 2-36 months of age with fever along with normal children of the same age without fever, plus immunocompromised children with fever along ...
David Jaffe, Erica Sodergren, George Weinstock, Gregory Storch, Gregory Storch, Jared Muenzer, Kristine Wylie, Max Arens, Richard Buller   +8 more
core   +2 more sources

The human gut virome is highly diverse, stable and individual-specific

bioRxiv, 2019
The human gut contains a vast array of viruses, mostly bacteriophages. The majority remain uncharacterised and their roles in shaping the gut microbiome and in impacting on human health remain poorly understood.
A. Shkoporov, Adam G. Clooney, T. Sutton, F. Ryan, K. Daly, J. A. Nolan, S. A. McDonnell, E. Khokhlova, L. Draper, Amanda Forde, Emma Guerin, Vimalkumar Velayudhan, R. Ross, C. Hill   +13 more
semanticscholar   +1 more source

Characterization of the Eukaryotic Virome of Mice from Different Sources

Microorganisms, 2021
Accumulating studies show that the host microbiome influences the development or progression of many diseases. The eukaryotic virome, as a key component of the microbiome, plays an important role in host health and disease in humans and animals ...
Chunye Zhang, Matt Burch, Kristine Wylie, Brandi Herter, Craig L. Franklin, Aaron C. Ericsson   +5 more
doaj   +1 more source

454-Pyrosequencing: A Molecular Battiscope for Freshwater Viral Ecology [PDF]

, 2010
Viruses, the most abundant biological entities on the planet, are capable of infecting organisms from all three branches of life, although the majority infect bacteria where the greatest degree of cellular diversity lies.
Ackermann, Alan J. McCarthy, Darren L. Smith, David J. Rooks, Foster, Heather E. Allison, James E. McDonald, Margulies, Martin J. Woodward, Ryan, Sambrook, Warren, White, Wilson   +13 more
core   +3 more sources

Cryptic and abundant marine viruses at the evolutionary origins of Earth’s RNA virome

Science, 2022
Whereas DNA viruses are known to be abundant, diverse, and commonly key ecosystem players, RNA viruses are insufficiently studied outside disease settings. In this study, we analyzed ≈28 terabases of Global Ocean RNA sequences to expand Earth’s RNA virus
A. Zayed, J. Wainaina, Guillermo Domínguez-Huerta, É. Pelletier, Jiarong Guo, Mohamed Mohssen, F. Tian, Akbar Adjie Pratama, B. Bolduc, Olivier Zablocki, Dylan Cronin, L. Solden, E. Delage, A. Alberti, J. Aury, Q. Carradec, C. da Silva, K. Labadie, J. Poulain, H. Ruscheweyh, Guillem Salazar, E. Shatoff, R. Bundschuh, K. Fredrick, L. Kubatko, Samuel Chaffron, Alexander I. Culley, S. Sunagawa, J. Kuhn, P. Wincker, M. Sullivan, S. Acinas, M. Babin, P. Bork, E. Boss, C. Bowler, G. Cochrane, C. de Vargas, G. Gorsky, L. Guidi, N. Grimsley, P. Hingamp, D. Iudicone, O. Jaillon, S. Kandels, L. Karp‐Boss, E. Karsenti, F. Not, H. Ogata, N. Poulton, S. Pesant, C. Sardet, S. Speich, L. Stemmann, M. Sullivan, Shinichi Sungawa, P. Wincker   +56 more
semanticscholar   +1 more source

Virome Capture Sequencing Enables Sensitive Viral Diagnosis and Comprehensive Virome Analysis [PDF]

mBio, 2015
ABSTRACT  Insensitivity and technical complexity have impeded the implementation of high-throughput nucleic acid sequencing in differential diagnosis of viral infections in clinical laboratories. Here, we describe the development of a virome capture sequencing platform for vertebrate viruses (VirCapSeq-VERT) that increases the sensitivity of ...
Thomas Briese, Amit Kapoor, Nischay Mishra, Komal Jain, Arvind Kumar, Omar J. Jabado, W. Ian Lipkin   +6 more
openaire   +3 more sources

Viral metagenomics of the gut virome of diarrheal children with Rotavirus A infection

Gut Microbes, 2023
Diarrhea is a leading cause of morbidity and mortality in children worldwide and represents a major dysbiosis event. Rotavirus has been recognized as a global leading pathogen of diarrhea.
Siwen Bao, Hao Wang, Wang Li, Haisheng Wu, Chunying Lu, Liang Yong, Qing Zhang, Xiang Lu, Min Zhao, Juan Lu, Jia Liu, Chukwudozie Kingsley Ikechukwu, Juan Xu, Ping Ni, Ying Xiong, Wen Zhang, Chenglin Zhou   +16 more
doaj   +1 more source

Viruses in Horses with Neurologic and Respiratory Diseases. [PDF]

, 2019
Metagenomics was used to identify viral sequences in the plasma and CSF (cerobrospinal fluid) of 13 horses with unexplained neurological signs and in the plasma and respiratory swabs of 14 horses with unexplained respiratory signs. Equine hepacivirus and
Altan, Eda, Barnum, Samantha, Delwart, Eric, Deng, Xutao, Li, Yanpeng, Pusterla, Nicola, Sabino-Santos, Gilberto, Sawaswong, Vorthon   +7 more
core   +1 more source